Comparison of procalcitonin, C-reactive protein, white blood cell counts and hemogram subparameters in community acquired pneumonia patients

Mustafa İlteriş Bardakçı; Gülhan Ayhan Albayrak

Makale detayları

Comparison of procalcitonin, C-reactive protein, white blood cell counts and hemogram subparameters in community acquired pneumonia patients

Yazarlar:

Mustafa İlteriş Bardakçı | Gülhan Ayhan Albayrak

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göğüs Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 6, pp.672-677

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001308702

pISSN:

2717-7505

Anahtar kelimeler:

Özet:

 Aims: Pneumonia is a clinically and radiologically detected inflammation of the lungs. Most of the pneumonia patients are community-acquired pneumonia cases. Hemogram and C-reactive protein CRP are commonly used to support diagnosis and follow-up of treatment. Procalcitonin is less accessible and expensive. And the use of hemogram subparameters is not very common. The aim of this study was to research the relationship between procalcitonin, CRP, White Blood Cell count WBC and hemogram subparameters in patients with CAP and the efficacy of new hematologic rates in differential diagnosis. Methods: Patients who were diagnosed with community acquired pneumonia by applying to the chest diseases outpatient clinic of our hospital were retrospectively analyzed. 67 patients who were clinically and radiologically diagnosed without noticing male or female were included in our study. Anamnesis data and co-morbidities of the cases were questioned. Procalcitonin, CRP and hemogram platelet-to-lymphocyte ratio PLR, neutrophil-to-lymphocyte ratio NLR and monocyte-to-lymphocyte ratio MLR were calculated and WBC value was examined were recorded. The obtained data were evaluated statistically and compared in terms of variables. Results: The mean age of our patients was 57 18-71 years; there were 41 61.19 female and 26 38.81 male patients. 36 53.73 of our patients had chronic diseases; 21 31.34 had heart disease, 23 34.32 had diabetes, and 6 8.95 had kidney failure. Patients; 48 71.64 procalcitonin, 56 83.58 CRP, 38 56.71 WBC, 52 77.61 NLR, 34 50.74 PLR and 38 56.71 MLR values were high. Procalcitonin, CRP and NLR values were significantly higher than other subparameters. The CRP and NLR values of patients with an additional chronic disease were higher than patients without co-morbidities. In the correlation analyses, there was a strong correlation between procalcitonin, CRP and NRL, but the correlation between the others was not significant. p0.001. Conclusion: Our study shows NLR from hemogram subparameters can be used safely in CAP patients. Procalcitonin is expensive test for. Considering that Procalcitonin is not available in primary care family health centers and CRP is found in some family health centers, the calculated use of NLR will support the diagnosis. Using fewer examinations in secondary and tertiary health facilities is also valuable in terms of reducing health costs.

 Aims: Pneumonia is a clinically and radiologically detected inflammation of the lungs. Most of the pneumonia patients are community-acquired pneumonia cases. Hemogram and C-reactive protein CRP are commonly used to support diagnosis and follow-up of treatment. Procalcitonin is less accessible and expensive. And the use of hemogram subparameters is not very common. The aim of this study was to research the relationship between procalcitonin, CRP, White Blood Cell count WBC and hemogram subparameters in patients with CAP and the efficacy of new hematologic rates in differential diagnosis. Methods: Patients who were diagnosed with community acquired pneumonia by applying to the chest diseases outpatient clinic of our hospital were retrospectively analyzed. 67 patients who were clinically and radiologically diagnosed without noticing male or female were included in our study. Anamnesis data and co-morbidities of the cases were questioned. Procalcitonin, CRP and hemogram platelet-to-lymphocyte ratio PLR, neutrophil-to-lymphocyte ratio NLR and monocyte-to-lymphocyte ratio MLR were calculated and WBC value was examined were recorded. The obtained data were evaluated statistically and compared in terms of variables. Results: The mean age of our patients was 57 18-71 years; there were 41 61.19 female and 26 38.81 male patients. 36 53.73 of our patients had chronic diseases; 21 31.34 had heart disease, 23 34.32 had diabetes, and 6 8.95 had kidney failure. Patients; 48 71.64 procalcitonin, 56 83.58 CRP, 38 56.71 WBC, 52 77.61 NLR, 34 50.74 PLR and 38 56.71 MLR values were high. Procalcitonin, CRP and NLR values were significantly higher than other subparameters. The CRP and NLR values of patients with an additional chronic disease were higher than patients without co-morbidities. In the correlation analyses, there was a strong correlation between procalcitonin, CRP and NRL, but the correlation between the others was not significant. p0.001. Conclusion: Our study shows NLR from hemogram subparameters can be used safely in CAP patients. Procalcitonin is expensive test for. Considering that Procalcitonin is not available in primary care family health centers and CRP is found in some family health centers, the calculated use of NLR will support the diagnosis. Using fewer examinations in secondary and tertiary health facilities is also valuable in terms of reducing health costs.

 Aims: Pneumonia is a clinically and radiologically detected inflammation of the lungs. Most of the pneumonia patients are community-acquired pneumonia cases. Hemogram and C-reactive protein CRP are commonly used to support diagnosis and follow-up of treatment. Procalcitonin is less accessible and expensive. And the use of hemogram subparameters is not very common. The aim of this study was to research the relationship between procalcitonin, CRP, White Blood Cell count WBC and hemogram subparameters in patients with CAP and the efficacy of new hematologic rates in differential diagnosis. Methods: Patients who were diagnosed with community acquired pneumonia by applying to the chest diseases outpatient clinic of our hospital were retrospectively analyzed. 67 patients who were clinically and radiologically diagnosed without noticing male or female were included in our study. Anamnesis data and co-morbidities of the cases were questioned. Procalcitonin, CRP and hemogram platelet-to-lymphocyte ratio PLR, neutrophil-to-lymphocyte ratio NLR and monocyte-to-lymphocyte ratio MLR were calculated and WBC value was examined were recorded. The obtained data were evaluated statistically and compared in terms of variables. Results: The mean age of our patients was 57 18-71 years; there were 41 61.19 female and 26 38.81 male patients. 36 53.73 of our patients had chronic diseases; 21 31.34 had heart disease, 23 34.32 had diabetes, and 6 8.95 had kidney failure. Patients; 48 71.64 procalcitonin, 56 83.58 CRP, 38 56.71 WBC, 52 77.61 NLR, 34 50.74 PLR and 38 56.71 MLR values were high. Procalcitonin, CRP and NLR values were significantly higher than other subparameters. The CRP and NLR values of patients with an additional chronic disease were higher than patients without co-morbidities. In the correlation analyses, there was a strong correlation between procalcitonin, CRP and NRL, but the correlation between the others was not significant. p0.001. Conclusion: Our study shows NLR from hemogram subparameters can be used safely in CAP patients. Procalcitonin is expensive test for. Considering that Procalcitonin is not available in primary care family health centers and CRP is found in some family health centers, the calculated use of NLR will support the diagnosis. Using fewer examinations in secondary and tertiary health facilities is also valuable in terms of reducing health costs.

 Amaç: Pnömoni, akciğerlerin klinik ve radyolojik olarak tespit edilen inflamasyonudur. Pnömoni hastalarının büyük kısmını toplumdan kazanılmış pnömoni CAP vakaları oluşturur. Tanıyı desteklemekte ve tedavinin takibinde hemogram ve C-reaktif proteinin CRP kullanımı yaygındır. Prokalsitonin, daha az erişilebilir ve pahalıdır. Ve hemogram alt parametrelerinin kullanımı pek yaygın değildir. Bu çalışmanın amacı, pnömonisi olan olgularda prokalsitonin, CRP, Beyaz Küre sayısı WBC ve hemogram alt parametreleri arasındaki ilişkiyi ve ayırıcı tanıda yeni hematolojik oranların etkinliğini araştırmaktır. Gereç ve Yöntem: Hastanemiz göğüs hastalıkları polikliniğine başvurarak toplumdan kazanılmış pnömoni tanısı alan olgular retrospektif olarak incelendi. Kadın-erkek fark etmeden klinik ve radyolojik olarak olarak tanı almış 67 hasta çalışmamıza dahil edildi. Olguların anamnez bilgileri ve ek hastalıkları sorgulandı. Hastaların prokalsitonin, CRP ve hemogram nötrofil-lenfosit oranı NLR, trombosit-lenfosit oranı PLR ve monosit-lenfosit oranı MLR hesaplandı ve WBC değerine bakıldı kaydedildi. Elde edilen veriler istatistik olarak değerlendirildi ve değişkenler açısından karşılaştırıldı. Bulgular: Hastalarımızın yaş ortalaması 57 18-71idi. 41 61,19 kadın ve 26 38,81 erkek hasta vardı. Hastalarımızın 36 53,73 tanesinin kronik hastalıkları mevcuttu; 21 31,34 tanesinde kalp hastalığı, 23 34,32 tanesinde diabet, 6 8,95 tanesinde böbrek yetmezliği vardı. Hastalarda; 48 71,64 prokalsitonin, 56 83,58 CRP, 38 56,71 WBC, 52 77,61 NLR, 34 50,74 PLR ve 38 56,71 MLR değerleri yüksekti. Prokalsitonin, CRP ve NLR değerleri diğer alt parametrelerinden daha anlamlı yüksekti. Ek bir kronik hastalığı olan hastaların CRP ve NLR değerleri ek hastalığı olmayan hastalardan daha yüksekti. Korelasyon analizlerinde prokalsitonin, CRP ve NRL arasında güçlü korelasyon vardı, diğerleri arasındaki korelasyon anlamlı değildi. p 0.001. Sonuç: Çalışmamız CAP hastalarında hemogram alt parametrelerinden NLRnin güvenle kullanılabileceğini göstermektedir. Prokalsitoninin pahalı bir testtir. Birinci basamak aile sağlığı merkezlerinde Prokalsitoninin bulunmadığı ve CRPnin bazı aile sağlığı merkezlerinde bulunduğu düşünüldüğünde NLRnin hesaplanarak kullanılmasının tanıyı destekleyeceğini göstermiştir. İkinci ve üçüncü basamak sağlık tesislerinde de daha az tetkik kullanmak sağlık giderlerini azaltmak yönünden değerlidir.

Makale detayları

Comparison of procalcitonin, C-reactive protein, white blood cell counts and hemogram subparameters in community acquired pneumonia patients

Yazarlar:

Mustafa İlteriş Bardakçı | Gülhan Ayhan Albayrak

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göğüs Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 6, pp.672-677

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001308702

pISSN:

2717-7505

Pneumonia

NLR

procalsitonin

CRPPnömoni

NLR

Prokalsitonin

CRP

Sayı

Makale detayları

Yazarlar: Mustafa İlteriş Bardakçı | Gülhan Ayhan Albayrak

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Göğüs Hastalıkları

Dergi: Journal of Medicine and Palliative Care Vol.4 Issue 6, pp.672-677

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001308702

pISSN: 2717-7505

Sayı

Yazarlar:

Mustafa İlteriş Bardakçı | Gülhan Ayhan Albayrak

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göğüs Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 6, pp.672-677

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001308702

pISSN:

2717-7505