Secondary pseudotumor cerebri in the pediatric population: clinical features, treatment, and prognosis

Olcay Güngör; Emine Ün; Beste Kıpcak; Osman Parça

Makale detayları

Secondary pseudotumor cerebri in the pediatric population: clinical features, treatment, and prognosis

Yazarlar:

Olcay Güngör | Emine Ün | Beste Kıpcak | Osman Parça

Yayıncı:

Pamukkale University

Ana Başlıklar:

Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Pamukkale Tıp Dergisi Vol.17 Issue 2, pp.279-284

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001300677

pISSN:

1308-0865

Anahtar kelimeler:

Özet:

 Purpose: Pseudotumor cerebri syndrome PTCS is characterized by elevated intracranial pressure ICP without intracranial mass, hydrocephalus, or abnormalities in cerebrospinal fluid CSF composition. In secondary PTCS sPTCS, there is a reason that increases the CSF pressure. The aim of this study is to evaluate the diagnosis, treatment, and follow-up of pediatric patients diagnosed with sPTCS. Materials and methods: This is a retrospective study conducted in a single-center tertiary pediatric hospital. We included patients aged 1-17 years who were diagnosed with sPTCS in a tertiary hospital between 2018 and 2023 and met the current diagnostic criteria for PTCS. We evaluated the complaints, etiology, ophthalmological evaluations, and treatment results of the cases. Results: Seventeen patients with a diagnosis of PTCS were included in the study. The mean age was 9.82 4.6. Of the patients, 9 56.2 were male and 8 43.7 were female. The most common symptoms were headache in 10 patients 62.5, nauseavomiting in 6 patients 37.5, and double vision in 5 patients 31.2. All patients had papilledema and 7 43.7 patients had sixth nerve palsy. Recurrence was observed in 3 16 patients. Optic nerve fenestration was performed in three patients as a second-line treatment. Conclusion: In cases that do not respond to medical treatment, optic nerve sheath fenestration may be a good treatment option.

 Purpose: Pseudotumor cerebri syndrome PTCS is characterized by elevated intracranial pressure ICP without intracranial mass, hydrocephalus, or abnormalities in cerebrospinal fluid CSF composition. In secondary PTCS sPTCS, there is a reason that increases the CSF pressure. The aim of this study is to evaluate the diagnosis, treatment, and follow-up of pediatric patients diagnosed with sPTCS. Materials and methods: This is a retrospective study conducted in a single-center tertiary pediatric hospital. We included patients aged 1-17 years who were diagnosed with sPTCS in a tertiary hospital between 2018 and 2023 and met the current diagnostic criteria for PTCS. We evaluated the complaints, etiology, ophthalmological evaluations, and treatment results of the cases. Results: Seventeen patients with a diagnosis of PTCS were included in the study. The mean age was 9.82 4.6. Of the patients, 9 56.2 were male and 8 43.7 were female. The most common symptoms were headache in 10 patients 62.5, nauseavomiting in 6 patients 37.5, and double vision in 5 patients 31.2. All patients had papilledema and 7 43.7 patients had sixth nerve palsy. Recurrence was observed in 3 16 patients. Optic nerve fenestration was performed in three patients as a second-line treatment. Conclusion: In cases that do not respond to medical treatment, optic nerve sheath fenestration may be a good treatment option.

 Purpose: Pseudotumor cerebri syndrome PTCS is characterized by elevated intracranial pressure ICP without intracranial mass, hydrocephalus, or abnormalities in cerebrospinal fluid CSF composition. In secondary PTCS sPTCS, there is a reason that increases the CSF pressure. The aim of this study is to evaluate the diagnosis, treatment, and follow-up of pediatric patients diagnosed with sPTCS. Materials and methods: This is a retrospective study conducted in a single-center tertiary pediatric hospital. We included patients aged 1-17 years who were diagnosed with sPTCS in a tertiary hospital between 2018 and 2023 and met the current diagnostic criteria for PTCS. We evaluated the complaints, etiology, ophthalmological evaluations, and treatment results of the cases. Results: Seventeen patients with a diagnosis of PTCS were included in the study. The mean age was 9.82 4.6. Of the patients, 9 56.2 were male and 8 43.7 were female. The most common symptoms were headache in 10 patients 62.5, nauseavomiting in 6 patients 37.5, and double vision in 5 patients 31.2. All patients had papilledema and 7 43.7 patients had sixth nerve palsy. Recurrence was observed in 3 16 patients. Optic nerve fenestration was performed in three patients as a second-line treatment. Conclusion: In cases that do not respond to medical treatment, optic nerve sheath fenestration may be a good treatment option.

 Amaç: Psödotümör serebri sendromu PTSS, intrakranyal kitle, hidrosefali veya beyin omurilik sıvısı BOS bileşiminde anormallikler olmadan yüksek kafa içi basıncı KİB ile karakterizedir. İkincil PTSSde sPTSS, BOS basıncını artıran bir neden vardır. Bu çalışmanın amacı sPTSS tanısı alan pediatrik hastaların tanı, tedavi ve takiplerinin değerlendirilmesidir. Gereç ve yöntem: Bu çalışma tek merkezli üçüncü basamak bir pediatri hastanesinde gerçekleştirilen retrospektif bir çalışmadır. 2018 ile 2023 yılları arasında üçüncü basamak bir hastanede sPTSS tanısı konan ve PTSS için mevcut tanı kriterlerini karşılayan 1-17 yaş arası hastaları dahil ettik. Olguların şikayetleri, etiyolojisi, oftalmolojik değerlendirmeleri ve tedavi sonuçları değerlendirildi. Bulgular: Çalışmaya PTSS tanısı alan 17 hasta dahil edildi. Ortalama yaş 9,82 4,6 idi. Hastaların 9u 56,2 erkek, 8i 43,7 kadındı. En sık görülen semptomlar 10 hastada 62,5 baş ağrısı, 6 hastada 37,5 bulantıkusma, 5 hastada 31,2 çift görme idi. Hastaların tamamında papilödem, 7 43,7 hastada ise altıncı sinir felci vardı. 3 16 hastada nüks görüldü. Üç hastaya ikinci basamak tedavi olarak optik sinir fenestrasyonu uygulandı. Sonuç: Medikal tedaviye yanıt alınamayan durumlarda optik sinir kılıfı fenestrasyonu iyi bir tedavi seçeneği olabilir.

Makale detayları

Secondary pseudotumor cerebri in the pediatric population: clinical features, treatment, and prognosis

Yazarlar:

Olcay Güngör | Emine Ün | Beste Kıpcak | Osman Parça

Yayıncı:

Pamukkale University

Ana Başlıklar:

Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Pamukkale Tıp Dergisi Vol.17 Issue 2, pp.279-284

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001300677

pISSN:

1308-0865

Optic nerve

pseudotumor cerebri

childOptik sinir

psödotümör serebri

çocuk

Sayı

Makale detayları

Secondary pseudotumor cerebri in the pediatric population: clinical features, treatment, and prognosis

Yazarlar: Olcay Güngör | Emine Ün | Beste Kıpcak | Osman Parça

Yayıncı: Pamukkale University

Ana Başlıklar: Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi: Pamukkale Tıp Dergisi Vol.17 Issue 2, pp.279-284

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001300677

pISSN: 1308-0865

Optic nerve

pseudotumor cerebri

childOptik sinir

psödotümör serebri

çocuk

Sayı

Yazarlar:

Olcay Güngör | Emine Ün | Beste Kıpcak | Osman Parça

Yayıncı:

Pamukkale University

Ana Başlıklar:

Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Pamukkale Tıp Dergisi Vol.17 Issue 2, pp.279-284

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001300677

pISSN:

1308-0865