Cytogenetic studies among mentally retarded children attending to special classes of mebaram in antalya province

İ. Keser; G. Lüleci; V. Keskin

Makale detayları

Cytogenetic studies among mentally retarded children attending to special classes of mebaram in antalya province

Yazarlar:

İ. Keser | G. Lüleci | V. Keskin

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 1998 Vol.11 Issue 4, pp.201-203

Belge Tipi:

Makale

Yayın Tarihi:

9/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000546870

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941

Özet:

 


Objective: The aim of this study was to investigate chromosomal abnormalities among mentally retarded children attending special classes at Antalya Guide and Research Center (MEBARAM).

Methods: One hundred and fifty-one children having different IQ and ages attending special classes of MEBARAM were screened for chromosomal abnormalities using cytogenetic techniques.

Results: The significant chromosomal abnormalities have been found as both major (3.97%) and heteromorphic (11.25%). The major chromosomal abnormalities were 46,Y, fra(X) (q27.3), 46,X, fra(X) (q27.3) with fra (3) (p14) and fra(16) (q23), 46,Y, fra(X) (p22), 46,XY, fra(8) (q22), and two cases 47.XX+21. Seventeen out of 151 children had different types of heterochromatic chromosomal abnormalities (1qh+, 10qh+, 15ph+, 16qh+, 21ph+, 22pss, Yqh+, Yqh-) and two had pericentric inversion of chromosome 9.

Conclusion: We suggest that children with learning difficulties should be screened for chromosomal abnormalities. Families with incidences of a child having fra (x) (q 27.3) and trisomy 21 chromosomal abnormalities should be quided towards prenatal diagnosis with genetic counseling.

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Makale detayları

Cytogenetic studies among mentally retarded children attending to special classes of mebaram in antalya province

Yazarlar: İ. Keser | G. Lüleci | V. Keskin

Yayıncı: Marmara University

Ana Başlıklar: Hastalıklar

Dergi: Marmara Medical Journal 1998 Vol.11 Issue 4, pp.201-203

Belge Tipi: Makale

Yayın Tarihi: 9/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000546870

Sıklık: Aylık

eISSN: 1309-9469

pISSN: 1019-1941

Sayı

Yazarlar:

İ. Keser | G. Lüleci | V. Keskin

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 1998 Vol.11 Issue 4, pp.201-203

Belge Tipi:

Makale

Yayın Tarihi:

9/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000546870

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941