Cryptogenic organizing pneumonia: clinical and radiological features, treatment outcomes of 17 patients, and review of the literature

Elif Yelda NİKSARLIOĞLU; Gülcihan Zehra ÖZKAN; Nur Dilek BAKAN; Sibel YURT; Lütfiye KILIÇ; Güngör ÇAMSARI

Makale detayları

Cryptogenic organizing pneumonia: clinical and radiological features, treatment outcomes of 17 patients, and review of the literature

Yazarlar:

Elif Yelda NİKSARLIOĞLU | Gülcihan Zehra ÖZKAN | Nur Dilek BAKAN | Sibel YURT | Lütfiye KILIÇ | Güngör ÇAMSARI

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1712-1718

Belge Tipi:

Makale

Yayın Tarihi:

11/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000751684

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: We evaluated patients with cryptogenic organizing pneumonia (COP) who attended our clinic.  Materials and methods: We retrospectively investigated the clinical and radiological findings, diagnostic methods, treatment, and follow-up outcomes of 17 patients who had been histopathologically diagnosed with COP.   Results: The mean age of the patients was 49.8 ± 10.4 years. The most common symptom was cough (n = 15; 88.2%) and the most common radiological finding (n = 10) was consolidation in the inferior lobes on thoracic computed tomography. The diagnosis of COP was made by open lung biopsy in 11 (64.7%) patients, transbronchial biopsy in 5 (29.4%), and video-assisted thoracoscopic surgery biopsy in 1 (5.9%). The mean follow-up period was 28.7 ± 25.0 (range: 3-85) months. Twelve patients received oral corticosteroid therapy and seven of them improved without any fibrotic changes. One patient refused treatment; a chest radiography of that patient was found to be normal at the end of the 20-month follow-up period. Three patients received no other therapy, as the lesion had been completely excised.   Conclusion: Common symptoms included cough and dyspnea, while the main radiological presentation of COP was consolidation. Corticosteroids are a good treatment option in general, but relapse may occur.

Makale detayları

Cryptogenic organizing pneumonia: clinical and radiological features, treatment outcomes of 17 patients, and review of the literature

Yazarlar: Elif Yelda NİKSARLIOĞLU | Gülcihan Zehra ÖZKAN | Nur Dilek BAKAN | Sibel YURT | Lütfiye KILIÇ | Güngör ÇAMSARI

Yayıncı: TUBITAK

Ana Başlıklar: Sağlık teşvikleri

Dergi: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1712-1718

Belge Tipi: Makale

Yayın Tarihi: 11/2016

Belge Dili: İngilizce

Document ID (Org No.): 2000751684

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Elif Yelda NİKSARLIOĞLU | Gülcihan Zehra ÖZKAN | Nur Dilek BAKAN | Sibel YURT | Lütfiye KILIÇ | Güngör ÇAMSARI

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1712-1718

Belge Tipi:

Makale

Yayın Tarihi:

11/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000751684

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144