Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults

Aslı Vatan; Gökcen Gürkök Budak; Ertuğrul Güçlü; Elif Köse; Aziz Öğütlü; Oğuz Karabay

Makale detayları

Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults

Yazarlar:

Aslı Vatan | Gökcen Gürkök Budak | Ertuğrul Güçlü | Elif Köse | Aziz Öğütlü | Oğuz Karabay

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Tıp Dergisi Vol.14 Issue 1, pp.11-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312765

pISSN:

2146-409X

Anahtar kelimeler:

Özet:

 Purpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 SARS-CoV-2. The present study investigated the predictive factors for disease severity in young adults. Method: Our study is a descriptive cross-sectional study. A total of 399 patients with SARS-CoV-2 aged under 60 who had been hospitalized at our hospital were retrospectively evaluated. Patients were stratified into mild, moderate, severe, and critical groups according to their respiratory rate, SpO2, and PaO2FiO2 levels. The relationship between the signs and symptoms on hospital admission and the disease severity was evaluated. Results: The patients were classified as mild n:112, moderate n:192, severe and critical n:95 according to disease severity. The mean age was 44. 43 of 399 patients were followed in the intensive care unit, and 17 patients died. According to the binary logistic regression analysis, advanced age, hypertension, dyspnea on admission, elevated CRP, decreased lymphocyte and eosinophil count, multiple bilateral ground glass appearances, and consolidation independently predicted the severity of the disease. Conclusion: The signs and symptoms should be evaluated in detail also in young patients with SARS-CoV-2. If risk factors are detected, they should be monitored more closely to predict a poor prognosis..

 Purpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 SARS-CoV-2. The present study investigated the predictive factors for disease severity in young adults. Method: Our study is a descriptive cross-sectional study. A total of 399 patients with SARS-CoV-2 aged under 60 who had been hospitalized at our hospital were retrospectively evaluated. Patients were stratified into mild, moderate, severe, and critical groups according to their respiratory rate, SpO2, and PaO2FiO2 levels. The relationship between the signs and symptoms on hospital admission and the disease severity was evaluated. Results: The patients were classified as mild n:112, moderate n:192, severe and critical n:95 according to disease severity. The mean age was 44. 43 of 399 patients were followed in the intensive care unit, and 17 patients died. According to the binary logistic regression analysis, advanced age, hypertension, dyspnea on admission, elevated CRP, decreased lymphocyte and eosinophil count, multiple bilateral ground glass appearances, and consolidation independently predicted the severity of the disease. Conclusion: The signs and symptoms should be evaluated in detail also in young patients with SARS-CoV-2. If risk factors are detected, they should be monitored more closely to predict a poor prognosis..

 Purpose: Advanced age is associated with a poor prognosis in Severe acute respiratory syndrome coronavirus-2 SARS-CoV-2. The present study investigated the predictive factors for disease severity in young adults. Method: Our study is a descriptive cross-sectional study. A total of 399 patients with SARS-CoV-2 aged under 60 who had been hospitalized at our hospital were retrospectively evaluated. Patients were stratified into mild, moderate, severe, and critical groups according to their respiratory rate, SpO2, and PaO2FiO2 levels. The relationship between the signs and symptoms on hospital admission and the disease severity was evaluated. Results: The patients were classified as mild n:112, moderate n:192, severe and critical n:95 according to disease severity. The mean age was 44. 43 of 399 patients were followed in the intensive care unit, and 17 patients died. According to the binary logistic regression analysis, advanced age, hypertension, dyspnea on admission, elevated CRP, decreased lymphocyte and eosinophil count, multiple bilateral ground glass appearances, and consolidation independently predicted the severity of the disease. Conclusion: The signs and symptoms should be evaluated in detail also in young patients with SARS-CoV-2. If risk factors are detected, they should be monitored more closely to predict a poor prognosis..

 Amaç: Coronavirus disease 2019 COVID 19 seyrinde ileri yaş varlığı hastalığın kötü gidişi ile ilişkilidir. Biz bu çalışmada 60 yaş altı genç hastalarda hastalığın şiddetini öngördüren faktörleri göstermeyi amaçladık. Gereç ve Yöntemler: Çalışmamızda mart  temmuz 2020 tarihleri arasında hastanemizde yatarak takip edilen COVID-19 tanılı 399 hasta retrospektif olarak değerlendirildi. Hastalara COVID-19 tanısı WHO güncel önerilerine göre konuldu. Hastaların hastaneye başvuru sırasındaki semptom ve bulguları ile hastalığın şiddeti arasındaki ilişki değerlendirildi. Bulgular: Hastalığın şiddetine göre; hastaların 112 si hafif, 192 si orta ve 95 i şiddetli ve kritik olarak değerlendirildi. Hastaların hepsi 60 yaş ve altında olup ortalama yaş 44 dü. Binary logistic regression analizine göre ileri yaş, hipertansiyon varlığı, hastaneye başvuru anında nefes darlığı olması, CRP yüksekliği, lenfosit ve eozinofil düşüklüğü , akciğer tomografisinde multipl bilateral buzlu cam tutulumu ve konsolidasyon varlığının hastalık ağırlığını bağımsız olarak öngördürdüğü saptandı. Sonuç: COVID-19 ile başvuran genç hastalarda da semptom ve bulgular ayrıntılı değerlendirilmeli ve risk faktörleri saptanırsa kötü gidiş öngörülerek hastalar daha yakından takip edilmelidir.

Makale detayları

Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults

Yazarlar:

Aslı Vatan | Gökcen Gürkök Budak | Ertuğrul Güçlü | Elif Köse | Aziz Öğütlü | Oğuz Karabay

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Tıp Dergisi Vol.14 Issue 1, pp.11-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312765

pISSN:

2146-409X

SARS-CoV-2

Young adult

Prognostic factorsSARS-CoV-2

Genç yetişkin

Prognostik faktörler

Sayı

Makale detayları

Predictive Factors For Severe And Critical Coronavirus Disease-19 In Young Adults

Yazarlar: Aslı Vatan | Gökcen Gürkök Budak | Ertuğrul Güçlü | Elif Köse | Aziz Öğütlü | Oğuz Karabay

Yayıncı: Sakarya University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Sakarya Tıp Dergisi Vol.14 Issue 1, pp.11-19

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001312765

pISSN: 2146-409X

SARS-CoV-2

Young adult

Prognostic factorsSARS-CoV-2

Genç yetişkin

Prognostik faktörler

Sayı

Yazarlar:

Aslı Vatan | Gökcen Gürkök Budak | Ertuğrul Güçlü | Elif Köse | Aziz Öğütlü | Oğuz Karabay

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Tıp Dergisi Vol.14 Issue 1, pp.11-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312765

pISSN:

2146-409X