Chemometric Optimization of Ultrasonic Assisted Extraction Parameters of Antioxidants from White Chicory (Cichorium intybus L.)

Açelya Aklan; Önder Aybastıer

Makale detayları

Chemometric Optimization of Ultrasonic Assisted Extraction Parameters of Antioxidants from White Chicory (Cichorium intybus L.)

Yazarlar:

Açelya Aklan | Önder Aybastıer

Yayıncı:

Gumushane University

Dergi:

Gümüşhane Üniversitesi Fen Bilimleri Dergisi Vol.13 Issue 3, pp.553-565

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001295853

pISSN:

2146-538X

Anahtar kelimeler:

Özet:

 In order to optimize the experimental conditions for the ultrasonic assisted extraction of phenolic compounds from chicory leaves, a five level five factor central composite design response surface methodology was used. Total phenolic content and antioxidant capacity were selected as the response and 48 experiments were performed using five independent variables; time min, HCl concentration molL, temperature ºC, liquidsolid ratio mLg and methanol concentration . As a result of optimization, optimum conditions, for maximum total phenolic content were determined as temperature 73 ºC, time 69 min, methanol 84, HCl concentration 0.57 molL and liquidsolid ratio 33.97 mLg. The optimum conditions, for maximum antioxidant capacity were temperature 73 ºC, time 69 min, methanol 85, HCl concentration 0.47 molL and liquidsolid ratio 33.99 mLg. The total phenolic content of white chicory extract obtained as a result of extraction under optimum conditions was determined as 33.50.5 mg GAEg dried plant and antioxidant capacity as 7.20.1 mg TEg dried plant.

 In order to optimize the experimental conditions for the ultrasonic assisted extraction of phenolic compounds from chicory leaves, a five level five factor central composite design response surface methodology was used. Total phenolic content and antioxidant capacity were selected as the response and 48 experiments were performed using five independent variables; time min, HCl concentration molL, temperature ºC, liquidsolid ratio mLg and methanol concentration . As a result of optimization, optimum conditions, for maximum total phenolic content were determined as temperature 73 ºC, time 69 min, methanol 84, HCl concentration 0.57 molL and liquidsolid ratio 33.97 mLg. The optimum conditions, for maximum antioxidant capacity were temperature 73 ºC, time 69 min, methanol 85, HCl concentration 0.47 molL and liquidsolid ratio 33.99 mLg. The total phenolic content of white chicory extract obtained as a result of extraction under optimum conditions was determined as 33.50.5 mg GAEg dried plant and antioxidant capacity as 7.20.1 mg TEg dried plant.

 In order to optimize the experimental conditions for the ultrasonic assisted extraction of phenolic compounds from chicory leaves, a five level five factor central composite design response surface methodology was used. Total phenolic content and antioxidant capacity were selected as the response and 48 experiments were performed using five independent variables; time min, HCl concentration molL, temperature ºC, liquidsolid ratio mLg and methanol concentration . As a result of optimization, optimum conditions, for maximum total phenolic content were determined as temperature 73 ºC, time 69 min, methanol 84, HCl concentration 0.57 molL and liquidsolid ratio 33.97 mLg. The optimum conditions, for maximum antioxidant capacity were temperature 73 ºC, time 69 min, methanol 85, HCl concentration 0.47 molL and liquidsolid ratio 33.99 mLg. The total phenolic content of white chicory extract obtained as a result of extraction under optimum conditions was determined as 33.50.5 mg GAEg dried plant and antioxidant capacity as 7.20.1 mg TEg dried plant.

 Beyaz hindiba yapraklarından fenolik bileşiklerin ultrasonik destekli ekstraksiyonu için deneysel koşulları optimize etmek amacıyla beş seviyeli beş faktörlü yanıt yüzey yöntemi kullanılmıştır. Yanıt verileri olarak toplam fenolik madde ve antioksidan kapasite seçilerek beş bağımsız değişken; süre dk, HCl derişimi molL, sıcaklık ºC, sıvıkatı oranı mLg ve metanol derişimi  kullanılarak 48 deney gerçekleştirilmiştir. Optimizasyon sonucunda en yüksek toplam fenolik madde için optimum koşullar, sıcaklık 73 ºC, süre 69 dk, metanol derişimi 84, HCl derişimi 0.57 molL ve sıvıkatı oranı 33.97 mLg olarak belirlenmiştir. En yüksek antioksidan kapasite için optimum koşullar sıcaklık 73 ºC, süre 69 dk, metanol derişimi 85, HCl derişimi 0.47 molL ve sıvıkatı oranı 33.99 mLg olarak belirlenmiştir. Belirlenen optimum koşullarda gerçekleştirilen ekstraksiyon sonucunda elde edilen beyaz hindiba ekstraktının toplam fenolik madde içeriği 33.50.5 mg GAEg kuru bitki ve antioksidan kapasite 7.20.1 mg TEg kuru bitki olarak bulunmuştur.

Makale detayları

Chemometric Optimization of Ultrasonic Assisted Extraction Parameters of Antioxidants from White Chicory (Cichorium intybus L.)

Yazarlar:

Açelya Aklan | Önder Aybastıer

Yayıncı:

Gumushane University

Dergi:

Gümüşhane Üniversitesi Fen Bilimleri Dergisi Vol.13 Issue 3, pp.553-565

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001295853

pISSN:

2146-538X

Antioxidant capacity

Cichorium intybus L.

Phenolic substance

Chemometric optimization

Response surface methodologyAntioksidan kapasite

Cichorium intybus L

Fenolik madde

Kemometrik optimizasyon

Yanıt yüzey yöntemi

Sayı

Makale detayları

Yazarlar: Açelya Aklan | Önder Aybastıer

Yayıncı: Gumushane University

Dergi: Gümüşhane Üniversitesi Fen Bilimleri Dergisi Vol.13 Issue 3, pp.553-565

Belge Tipi: Makale

Yayın Tarihi: 7/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001295853

pISSN: 2146-538X

Sayı

Yazarlar:

Açelya Aklan | Önder Aybastıer

Yayıncı:

Gumushane University

Dergi:

Gümüşhane Üniversitesi Fen Bilimleri Dergisi Vol.13 Issue 3, pp.553-565

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001295853

pISSN:

2146-538X