INVESTIGATION OF ZONULIN LEVELS IN DOGS INFECTED WITH CANINE DISTEMPER VIRUS

Ethem Mert Çöllü; Tahir Özalp; Songül Erdoğan; Kerem Ural; Hasan Erdoğan

Makale detayları

INVESTIGATION OF ZONULIN LEVELS IN DOGS INFECTED WITH CANINE DISTEMPER VIRUS

Yazarlar:

Ethem Mert Çöllü | Tahir Özalp | Songül Erdoğan | Kerem Ural | Hasan Erdoğan

Yayıncı:

Yozgat Bozok University

Ana Başlıklar:

Veteriner İç Hastalıkları

Dergi:

Bozok Veterinary Sciences Vol.5 Issue 2, pp.55-61

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334817

pISSN:

2757-5179

Anahtar kelimeler:

Özet:

 This study aims to investigate the impact of Canine Distemper Virus CDV infection on plasma zonulin levels, focusing particularly on how this effect varies in patients exhibiting neurological symptoms. The research involved the evaluation of 20 infected dogs and 10 healthy control dogs, all of which were brought to the Internal Medicine Clinics of Aydın Adnan Menderes University Veterinary Faculty for diagnosis and treatment. The zonulin levels in the infected dogs were found to be significantly higher compared to the healthy controls. These findings suggest that the virus affects not only the gastrointestinal barrier but also the blood-brain barrier. This supports the hypothesis that these changes may contribute to the increased permeability of the blood-brain barrier.

 This study aims to investigate the impact of Canine Distemper Virus CDV infection on plasma zonulin levels, focusing particularly on how this effect varies in patients exhibiting neurological symptoms. The research involved the evaluation of 20 infected dogs and 10 healthy control dogs, all of which were brought to the Internal Medicine Clinics of Aydın Adnan Menderes University Veterinary Faculty for diagnosis and treatment. The zonulin levels in the infected dogs were found to be significantly higher compared to the healthy controls. These findings suggest that the virus affects not only the gastrointestinal barrier but also the blood-brain barrier. This supports the hypothesis that these changes may contribute to the increased permeability of the blood-brain barrier.

 This study aims to investigate the impact of Canine Distemper Virus CDV infection on plasma zonulin levels, focusing particularly on how this effect varies in patients exhibiting neurological symptoms. The research involved the evaluation of 20 infected dogs and 10 healthy control dogs, all of which were brought to the Internal Medicine Clinics of Aydın Adnan Menderes University Veterinary Faculty for diagnosis and treatment. The zonulin levels in the infected dogs were found to be significantly higher compared to the healthy controls. These findings suggest that the virus affects not only the gastrointestinal barrier but also the blood-brain barrier. This supports the hypothesis that these changes may contribute to the increased permeability of the blood-brain barrier.

 Bu çalışma, Canine Distemper Virüs CDV enfeksiyonunun plazma zonulin seviyeleri üzerindeki etkisini, özellikle nörolojik semptomlar gösteren hastalarda nasıl değiştiğini araştırmayı amaçlamaktadır. Araştırmada, Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi İç Hastalıkları Klinikleri ne tanı ve tedavi için getirilen 20 enfekte köpek ve 10 sağlıklı kontrol köpeği değerlendirilmiştir. Enfekte köpeklerde zonulin seviyeleri, sağlıklı kontrollerden anlamlı derecede yüksek bulunmuştur. Bu bulgular, virüsün sadece gastrointestinal bariyeri değil, aynı zamanda kan-beyin bariyerini de etkilediğini önermektedir. Bu değişikliklerin kan-beyin bariyerinin artan geçirgenliğine katkıda bulunabileceği hipotezini desteklemektedir.

Makale detayları

INVESTIGATION OF ZONULIN LEVELS IN DOGS INFECTED WITH CANINE DISTEMPER VIRUS

Yazarlar:

Ethem Mert Çöllü | Tahir Özalp | Songül Erdoğan | Kerem Ural | Hasan Erdoğan

Yayıncı:

Yozgat Bozok University

Ana Başlıklar:

Veteriner İç Hastalıkları

Dergi:

Bozok Veterinary Sciences Vol.5 Issue 2, pp.55-61

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334817

pISSN:

2757-5179

Distemper

Dog

Gut permeability

ZonulinBağırsak geçirgenliği

Distemper

Köpek

Zonulin.

Sayı

Makale detayları

Yazarlar: Ethem Mert Çöllü | Tahir Özalp | Songül Erdoğan | Kerem Ural | Hasan Erdoğan

Yayıncı: Yozgat Bozok University

Ana Başlıklar: Veteriner İç Hastalıkları

Dergi: Bozok Veterinary Sciences Vol.5 Issue 2, pp.55-61

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001334817

pISSN: 2757-5179

Sayı

Yazarlar:

Ethem Mert Çöllü | Tahir Özalp | Songül Erdoğan | Kerem Ural | Hasan Erdoğan

Yayıncı:

Yozgat Bozok University

Ana Başlıklar:

Veteriner İç Hastalıkları

Dergi:

Bozok Veterinary Sciences Vol.5 Issue 2, pp.55-61

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334817

pISSN:

2757-5179