The Relationship Between Pulse Pressure And Dementia In Older Adults: A Cross-Sectional Study

Mehmet Selman Öntan; Fatma Sena Dost; Derya Kaya; Ahmet Turan Işık

Makale detayları

The Relationship Between Pulse Pressure And Dementia In Older Adults: A Cross-Sectional Study

Yazarlar:

Mehmet Selman Öntan | Fatma Sena Dost | Derya Kaya | Ahmet Turan Işık

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Geriatrics and Gerontology

Dergi:

Journal of Basic and Clinical Health Sciences Vol.9 Issue 2, pp.413-418

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349160

pISSN:

2564-7288

Anahtar kelimeler:

Özet:

 Purpose: As a risk factor for cardiovascular disease, wide pulse pressure PP may be related to cognitive impairment across the lifespan. Methods: A total of 313 patients with dementia and 1117 cognitively healthy individuals were included in this study. Dementia was diagnosed according to The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Blood pressure BP measurements, demographics, comorbidities, laboratory results, and comprehensive geriatric assessment parameters were assessed. Results: While the mean age of the patients and the number of drugs were higher; the frequency of female sex and years of education were lower in the dementia group than in the control group p0.001 for each. Also, the Mini Nutritional Assessment scores, estimated Glomerular Filtration Rate, folate, and 25 hydroxy vitamin D levels were lower in the dementia group than in the control group p0.001;p0.001;p0.001 and p0.001, respectively. While the dementia group had wider PP than controlsp0.006; there was no difference between the groups in systolic, diastolic, and mean arterial BP values. When confounding factors were adjusted, the relationship between PP and dementia was significant p0.032. PP was positively correlated with dementiap0.01. Conclusion: This study showed that dementia seems to be related to wider pulse pressure in older adults. Healthcare professionals should be aware of the importance of pulse pressure in geriatric practice.

 Purpose: As a risk factor for cardiovascular disease, wide pulse pressure PP may be related to cognitive impairment across the lifespan. Methods: A total of 313 patients with dementia and 1117 cognitively healthy individuals were included in this study. Dementia was diagnosed according to The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Blood pressure BP measurements, demographics, comorbidities, laboratory results, and comprehensive geriatric assessment parameters were assessed. Results: While the mean age of the patients and the number of drugs were higher; the frequency of female sex and years of education were lower in the dementia group than in the control group p0.001 for each. Also, the Mini Nutritional Assessment scores, estimated Glomerular Filtration Rate, folate, and 25 hydroxy vitamin D levels were lower in the dementia group than in the control group p0.001;p0.001;p0.001 and p0.001, respectively. While the dementia group had wider PP than controlsp0.006; there was no difference between the groups in systolic, diastolic, and mean arterial BP values. When confounding factors were adjusted, the relationship between PP and dementia was significant p0.032. PP was positively correlated with dementiap0.01. Conclusion: This study showed that dementia seems to be related to wider pulse pressure in older adults. Healthcare professionals should be aware of the importance of pulse pressure in geriatric practice.

 Purpose: As a risk factor for cardiovascular disease, wide pulse pressure PP may be related to cognitive impairment across the lifespan. Methods: A total of 313 patients with dementia and 1117 cognitively healthy individuals were included in this study. Dementia was diagnosed according to The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Blood pressure BP measurements, demographics, comorbidities, laboratory results, and comprehensive geriatric assessment parameters were assessed. Results: While the mean age of the patients and the number of drugs were higher; the frequency of female sex and years of education were lower in the dementia group than in the control group p0.001 for each. Also, the Mini Nutritional Assessment scores, estimated Glomerular Filtration Rate, folate, and 25 hydroxy vitamin D levels were lower in the dementia group than in the control group p0.001;p0.001;p0.001 and p0.001, respectively. While the dementia group had wider PP than controlsp0.006; there was no difference between the groups in systolic, diastolic, and mean arterial BP values. When confounding factors were adjusted, the relationship between PP and dementia was significant p0.032. PP was positively correlated with dementiap0.01. Conclusion: This study showed that dementia seems to be related to wider pulse pressure in older adults. Healthcare professionals should be aware of the importance of pulse pressure in geriatric practice.

 Purpose: As a risk factor for cardiovascular disease, wide pulse pressure PP may be related to cognitive impairment across the lifespan. Methods: A total of 313 patients with dementia and 1117 cognitively healthy individuals were included in this study. Dementia was diagnosed according to The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Blood pressure BP measurements, demographics, comorbidities, laboratory results, and comprehensive geriatric assessment parameters were assessed. Results: While the mean age of the patients and the number of drugs were higher; the frequency of female sex and years of education were lower in the dementia group than in the control group p0.001 for each. Also, the Mini Nutritional Assessment scores, estimated Glomerular Filtration Rate, folate, and 25 hydroxy vitamin D levels were lower in the dementia group than in the control group p0.001;p0.001;p0.001 and p0.001, respectively. While the dementia group had wider PP than controlsp0.006; there was no difference between the groups in systolic, diastolic, and mean arterial BP values. When confounding factors were adjusted, the relationship between PP and dementia was significant p0.032. PP was positively correlated with dementiap0.01. Conclusion: This study showed that dementia seems to be related to wider pulse pressure in older adults. Healthcare professionals should be aware of the importance of pulse pressure in geriatric practice.

Makale detayları

The Relationship Between Pulse Pressure And Dementia In Older Adults: A Cross-Sectional Study

Yazarlar:

Mehmet Selman Öntan | Fatma Sena Dost | Derya Kaya | Ahmet Turan Işık

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Geriatrics and Gerontology

Dergi:

Journal of Basic and Clinical Health Sciences Vol.9 Issue 2, pp.413-418

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349160

pISSN:

2564-7288

Dementia

Pulse Pressure

Mean Arterial Blood Pressure

Older Adults

Sayı

Makale detayları

The Relationship Between Pulse Pressure And Dementia In Older Adults: A Cross-Sectional Study

Yazarlar: Mehmet Selman Öntan | Fatma Sena Dost | Derya Kaya | Ahmet Turan Işık

Yayıncı: Dokuz Eylul University

Ana Başlıklar: Geriatrics and Gerontology

Dergi: Journal of Basic and Clinical Health Sciences Vol.9 Issue 2, pp.413-418

Belge Tipi: Makale

Yayın Tarihi: 5/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001349160

pISSN: 2564-7288

Dementia

Pulse Pressure

Mean Arterial Blood Pressure

Older Adults

Sayı

Yazarlar:

Mehmet Selman Öntan | Fatma Sena Dost | Derya Kaya | Ahmet Turan Işık

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Geriatrics and Gerontology

Dergi:

Journal of Basic and Clinical Health Sciences Vol.9 Issue 2, pp.413-418

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349160

pISSN:

2564-7288