Oxidative Cyclisation of 3-Oxopropanenitriles Mediated Manganese(III) Acetate with 2-Thienyl Substituted Alkenes

Mehmet YILMAZ; Neşe UZUNALİOĞLU; Mehtap YAKUT; A. Tarık PEKEL

Makale detayları

Oxidative Cyclisation of 3-Oxopropanenitriles Mediated Manganese(III) Acetate with 2-Thienyl Substituted Alkenes

Yazarlar:

Mehmet YILMAZ | Neşe UZUNALİOĞLU | Mehtap YAKUT | A. Tarık PEKEL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2008 Vol.32 Issue 4, pp.411-422

Belge Tipi:

Makale

Yayın Tarihi:

3/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000728462

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

The oxidative cyclisation of 3-oxopropanenitriles 1a-g with  alkenes 2a-c containing 2-thienyl group by manganese(III) acetate was  studied.  Treatment of 3-oxopropanenitriles 1a-d with 2-[(E)-2-phenylvinyl]  thiophene 2a gave 4-phenyl-5-(2-thienyl)-4,5-dihydrofuran-3-carbonitriles   3a-d in moderate yields (52%-60%).  5-(2-thienyl) substituted  4,5-dihydrofuran-3-carbonitriles 3e-i were obtained by the oxidative  cyclisation of these 3-oxopropanenitriles with 2-[(E)-1-methyl-2-  phenylvinyl]thiophene 2b in good yields (54%-68%). In addition,   the reactions of 2-(1-phenylvinyl)thiophene 2c with various   3-oxopropanenitriles produced 4,5-dihydrofurans 3j-n containing   heterocycle in 77%-91% yields.

 

The oxidative cyclisation of 3-oxopropanenitriles 1a-g with  alkenes 2a-c containing 2-thienyl group by manganese(III) acetate was  studied.  Treatment of 3-oxopropanenitriles 1a-d with 2-[(E)-2-phenylvinyl]  thiophene 2a gave 4-phenyl-5-(2-thienyl)-4,5-dihydrofuran-3-carbonitriles   3a-d in moderate yields (52%-60%).  5-(2-thienyl) substituted  4,5-dihydrofuran-3-carbonitriles 3e-i were obtained by the oxidative  cyclisation of these 3-oxopropanenitriles with 2-[(E)-1-methyl-2-  phenylvinyl]thiophene 2b in good yields (54%-68%). In addition,   the reactions of 2-(1-phenylvinyl)thiophene 2c with various   3-oxopropanenitriles produced 4,5-dihydrofurans 3j-n containing   heterocycle in 77%-91% yields.

Makale detayları

Oxidative Cyclisation of 3-Oxopropanenitriles Mediated Manganese(III) Acetate with 2-Thienyl Substituted Alkenes

Yazarlar: Mehmet YILMAZ | Neşe UZUNALİOĞLU | Mehtap YAKUT | A. Tarık PEKEL

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2008 Vol.32 Issue 4, pp.411-422

Belge Tipi: Makale

Yayın Tarihi: 3/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000728462

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Mehmet YILMAZ | Neşe UZUNALİOĞLU | Mehtap YAKUT | A. Tarık PEKEL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2008 Vol.32 Issue 4, pp.411-422

Belge Tipi:

Makale

Yayın Tarihi:

3/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000728462

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527