THE DIAGNOSTIC ROLE OF PET/CT IN PATIENTS WITH MALIGNANT PLEURAL EFFUSION

Süleyman Emre Akın; Hasan Emre Yıldırım; Samet Yağcı; Umut Otlu; Hasan Ekrem Çamaş; Mehmet Erdoğan; İsa Döngel; Sevim Süreyya Şengül; Rasih Yazkan

Makale detayları

THE DIAGNOSTIC ROLE OF PET/CT IN PATIENTS WITH MALIGNANT PLEURAL EFFUSION

Yazarlar:

Süleyman Emre Akın | Hasan Emre Yıldırım | Samet Yağcı | Umut Otlu | Hasan Ekrem Çamaş | Mehmet Erdoğan | İsa Döngel | Sevim Süreyya Şengül | Rasih Yazkan

Yayıncı:

Selcuk University

Ana Başlıklar:

Nükleer Tıp | Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.35 Issue 2, pp.369-373

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345148

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 Abstract Background: Malignant pleural effusion is defined as the presence of malignant cells in pleural effusion PE or biopsy specimens and occurs in 15 of all cancer patients. The most common cause is lung cancer in men and breast cancer in women. The reason for hospital admission is usually shortness of breath. The main goal of treatment is to relieve symptoms and prevent recurrence. PETCT is an imaging system that combines the metabolic properties of PET with the morphologic properties of computed tomography. The patient can be managed more rapidly if malignant effusion can be detected on PETCT. In this study, we aimed to predict the diagnostic impact of metabolic uptake of fluid in patients with malignant pleural effusion. Methods: In our study, we aimed to find the contribution of PETCT to the diagnosis of malignant pleural effusion by examining patients between 18 and 90 years of age who had malignancy as a result of pleural cytology and who underwent PETCT with a primary diagnosis of malignancy. 26 patients were evaluated. The values analyzed were; the presence of PE FDG uptake, the presence of single or double uptake in PE, the presence of multiple pulmonary nodules, the presence of pleural thickness PT increase, PK diameter, the presence of FDG uptake in PK, primary pathology being lung or other organ, PE Standardized Uptake Value SUV max, PE SUVmax Med SUVmax, PE SUVmax Liver SUVmax, PE SUVmax primary tumor SUVmax, primary tumor SUV values. Results: 6 of 26 patients had bilateral effusions and 12 patients had FDG uptake. 5 patients had pleural thickening and 4 of them had pleural uptake. In the ROC analysis, PE SUVmax, PE SUV  Med SUV, PE SUV  Liver SUV, and PE SUV  Primary tm SUV values were found to be significant in terms of predicting PE FDG uptake, while PT diameter was not significant. Conclusions: Patients with malignant pleural effusion have a short life expectancy. Diagnosis and treatment management of patients should be performed effectively and rapidly. PETCT can be used as a noninvasive diagnostic method for this purpose. Therefore, if further studies are performed, PETCT in the diagnosis of MPE will contribute to patient management.

 Abstract Background: Malignant pleural effusion is defined as the presence of malignant cells in pleural effusion PE or biopsy specimens and occurs in 15 of all cancer patients. The most common cause is lung cancer in men and breast cancer in women. The reason for hospital admission is usually shortness of breath. The main goal of treatment is to relieve symptoms and prevent recurrence. PETCT is an imaging system that combines the metabolic properties of PET with the morphologic properties of computed tomography. The patient can be managed more rapidly if malignant effusion can be detected on PETCT. In this study, we aimed to predict the diagnostic impact of metabolic uptake of fluid in patients with malignant pleural effusion. Methods: In our study, we aimed to find the contribution of PETCT to the diagnosis of malignant pleural effusion by examining patients between 18 and 90 years of age who had malignancy as a result of pleural cytology and who underwent PETCT with a primary diagnosis of malignancy. 26 patients were evaluated. The values analyzed were; the presence of PE FDG uptake, the presence of single or double uptake in PE, the presence of multiple pulmonary nodules, the presence of pleural thickness PT increase, PK diameter, the presence of FDG uptake in PK, primary pathology being lung or other organ, PE Standardized Uptake Value SUV max, PE SUVmax Med SUVmax, PE SUVmax Liver SUVmax, PE SUVmax primary tumor SUVmax, primary tumor SUV values. Results: 6 of 26 patients had bilateral effusions and 12 patients had FDG uptake. 5 patients had pleural thickening and 4 of them had pleural uptake. In the ROC analysis, PE SUVmax, PE SUV  Med SUV, PE SUV  Liver SUV, and PE SUV  Primary tm SUV values were found to be significant in terms of predicting PE FDG uptake, while PT diameter was not significant. Conclusions: Patients with malignant pleural effusion have a short life expectancy. Diagnosis and treatment management of patients should be performed effectively and rapidly. PETCT can be used as a noninvasive diagnostic method for this purpose. Therefore, if further studies are performed, PETCT in the diagnosis of MPE will contribute to patient management.

 Abstract Background: Malignant pleural effusion is defined as the presence of malignant cells in pleural effusion PE or biopsy specimens and occurs in 15 of all cancer patients. The most common cause is lung cancer in men and breast cancer in women. The reason for hospital admission is usually shortness of breath. The main goal of treatment is to relieve symptoms and prevent recurrence. PETCT is an imaging system that combines the metabolic properties of PET with the morphologic properties of computed tomography. The patient can be managed more rapidly if malignant effusion can be detected on PETCT. In this study, we aimed to predict the diagnostic impact of metabolic uptake of fluid in patients with malignant pleural effusion. Methods: In our study, we aimed to find the contribution of PETCT to the diagnosis of malignant pleural effusion by examining patients between 18 and 90 years of age who had malignancy as a result of pleural cytology and who underwent PETCT with a primary diagnosis of malignancy. 26 patients were evaluated. The values analyzed were; the presence of PE FDG uptake, the presence of single or double uptake in PE, the presence of multiple pulmonary nodules, the presence of pleural thickness PT increase, PK diameter, the presence of FDG uptake in PK, primary pathology being lung or other organ, PE Standardized Uptake Value SUV max, PE SUVmax Med SUVmax, PE SUVmax Liver SUVmax, PE SUVmax primary tumor SUVmax, primary tumor SUV values. Results: 6 of 26 patients had bilateral effusions and 12 patients had FDG uptake. 5 patients had pleural thickening and 4 of them had pleural uptake. In the ROC analysis, PE SUVmax, PE SUV  Med SUV, PE SUV  Liver SUV, and PE SUV  Primary tm SUV values were found to be significant in terms of predicting PE FDG uptake, while PT diameter was not significant. Conclusions: Patients with malignant pleural effusion have a short life expectancy. Diagnosis and treatment management of patients should be performed effectively and rapidly. PETCT can be used as a noninvasive diagnostic method for this purpose. Therefore, if further studies are performed, PETCT in the diagnosis of MPE will contribute to patient management.

 Abstract Background: Malign plevral efüzyon , plevral efüzyon PE veya biyopsi örneklerinde malign hücrelerin varlığı olarak tanımlanır ve tüm kanser hastalarının 15 inde görülür. Erkeklerde en sık sebep akciğer kanseri iken kadınlarda meme kanseridir . Hastaneye başvuru sebebi genelde nefes darlığıdır . Tedavide ana hedef semptomları ortadan kaldırmak ve tekrarlamasını önlemektir. PETBT, PET in metabolik özellikleri bilgisayarlı tomografinin morfolojik özelliklerini birleştiren görüntüleme sistemidir. PETBT de malign efüzyon tespit edilebilirse hastanın yönetimi daha hızlı yapılabilir. Biz bu çalışmada malign plevral efüzyon olan hastalarda sıvının metabolik tutulumunun tanıdaki etkisini öngörmeyi amaçladık. Methods: Çalışmamızda plevral sitoloji sonucu malignitesi olup primer malignite tanısı olan PETBT çekilmiş 18-90 yaş aralığında hastaları inceleyerek malign plevral efüzyon için PETBTnin tanıya katkısını bulmayı amaçladık. 26 tane hastayı değerlendirmeye aldık. Analize tabi tutulan değerler; PE FDG tutulumu varlığı, PEde tek ya da çift tutulum olması, çoklu pulmoner nodül varlığı, plevral kalınlık PK artışı varlığı, PK çapı, PKda FDG tutulumu varlığı, primer patolojinin akciğer veya diğer organ olması, PE Standardized Uptake Value SUV max, PE SUVmax Med SUVmax, PE SUVmax Karaciğer SUVmax, PE SUVmax primer tümör SUVmax, primer tümör SUV değerleridir. Results: 26 hastanın 6 sında efüzyon çift taraflıydı ve 12 hastanın efüzyonunda FDG tutulumu vardı. 5 hastada plevral kalınlaşma vardı bunların 4 ünde plevra tutulumu mevcuttu. Yapılan ROC analizinde PE FDG tutulumunu tahmin bakımından; PE SUVmax, PE SUV  Med SUV, PE SUV  Liver SUV, PE SUV  Primer tm SUV değerlerinin anlamlı olduğu, PK çapının anlamlı olmadığı görülmüştür. Conclusions: Malign plevral efüzyon hastalarında kısa bir yaşam süresi söz konusudur. Hastaların tanı ve tedavi yönetiminin etkin ve hızlı bir şekilde yapılması gerekmektedir. PETBT bu amaçla noninvaziv bir tanı yöntemi olarak kullanılabilir. Bu nedenle ileri çalışmaların yapılması halinde MPE tanısında PETBT nin hasta yönetimine katkısı olacaktır.

Makale detayları

THE DIAGNOSTIC ROLE OF PET/CT IN PATIENTS WITH MALIGNANT PLEURAL EFFUSION

Yazarlar:

Süleyman Emre Akın | Hasan Emre Yıldırım | Samet Yağcı | Umut Otlu | Hasan Ekrem Çamaş | Mehmet Erdoğan | İsa Döngel | Sevim Süreyya Şengül | Rasih Yazkan

Yayıncı:

Selcuk University

Ana Başlıklar:

Nükleer Tıp | Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.35 Issue 2, pp.369-373

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345148

pISSN:

2602-3741

malignant pleural effusion

PET/CT

18F-fluorodeoxyglucose

cancer

pleural metastasismalign plevral efüzyon

PET/BT

18F-florodeoksiglukoz

kanser

plevral metastaz

Sayı

Makale detayları

Yazarlar: Süleyman Emre Akın | Hasan Emre Yıldırım | Samet Yağcı | Umut Otlu | Hasan Ekrem Çamaş | Mehmet Erdoğan | İsa Döngel | Sevim Süreyya Şengül | Rasih Yazkan

Yayıncı: Selcuk University

Ana Başlıklar: Nükleer Tıp | Klinik Tıp Bilimleri (Diğer)

Dergi: Genel Tıp Dergisi Vol.35 Issue 2, pp.369-373

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001345148

pISSN: 2602-3741

Sayı

Yazarlar:

Süleyman Emre Akın | Hasan Emre Yıldırım | Samet Yağcı | Umut Otlu | Hasan Ekrem Çamaş | Mehmet Erdoğan | İsa Döngel | Sevim Süreyya Şengül | Rasih Yazkan

Yayıncı:

Selcuk University

Ana Başlıklar:

Nükleer Tıp | Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.35 Issue 2, pp.369-373

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345148

pISSN:

2602-3741