Effects of Scorzonera cinerea on Immune System and Hematological Parameters in Short-Term Hyperglycemia

Mehmet Ali Temiz

Makale detayları

Effects of Scorzonera cinerea on Immune System and Hematological Parameters in Short-Term Hyperglycemia

Yazarlar:

Mehmet Ali Temiz

Yayıncı:

Marmara University

Ana Başlıklar:

Health Care Administration

Dergi:

Clinical and Experimental Health Sciences Vol.13 Issue 1, pp.129-136

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286321

pISSN:

2459-1459

Anahtar kelimeler:

Özet:

 Objective: Objective: Medicinal herbs offer natural remedies for various ailments because of their comprehensive effects. Scorzonera cinerea L. Sc is an edible wild plant and is used in traditional medicine against various diseases. The purpose of this study was to investigate the immune system effects of S. cinerea radical leaf extract in diabetic rats. Methods: The 5 groups were formed  Control, Diabetic, Sc-Dried, Sc-Frozen, and Acarbose. Adenosine deaminase ADA, xanthine oxidase XO, and myeloperoxidase MPO activities in liver and kidney tissues were analyzed. Hematological parameters were also evaluated. Results: ADA, XO, and MPO activities in both tissues significantly increased in diabetic conditions. However, Sc treatments significantly decreased liver ADA, liver and kidney XO, and liver and kidney MPO activities. There was no significant change in red blood cell RBC parameters. Although platelet PLT count and MPV were raised in the diabetic group, these parameters were reduced with Sc-Dried and Sc-Frozen treatment. While lymphocyte LYM significantly decreased in defense cells in the diabetic group, neutrophil NEU, monocyte MO, and eosinophil EOS elevated. However, a significant decrease was observed in NEU and EOS with Sc treatment. Conclusion: S. cinerea treatment can exert a potential immunoregulatory effect in diabetes. Thus, S. cinerea can be considered as an adjuvant to augment immune system on diabetes.

 Objective: Objective: Medicinal herbs offer natural remedies for various ailments because of their comprehensive effects. Scorzonera cinerea L. Sc is an edible wild plant and is used in traditional medicine against various diseases. The purpose of this study was to investigate the immune system effects of S. cinerea radical leaf extract in diabetic rats. Methods: The 5 groups were formed  Control, Diabetic, Sc-Dried, Sc-Frozen, and Acarbose. Adenosine deaminase ADA, xanthine oxidase XO, and myeloperoxidase MPO activities in liver and kidney tissues were analyzed. Hematological parameters were also evaluated. Results: ADA, XO, and MPO activities in both tissues significantly increased in diabetic conditions. However, Sc treatments significantly decreased liver ADA, liver and kidney XO, and liver and kidney MPO activities. There was no significant change in red blood cell RBC parameters. Although platelet PLT count and MPV were raised in the diabetic group, these parameters were reduced with Sc-Dried and Sc-Frozen treatment. While lymphocyte LYM significantly decreased in defense cells in the diabetic group, neutrophil NEU, monocyte MO, and eosinophil EOS elevated. However, a significant decrease was observed in NEU and EOS with Sc treatment. Conclusion: S. cinerea treatment can exert a potential immunoregulatory effect in diabetes. Thus, S. cinerea can be considered as an adjuvant to augment immune system on diabetes.

 Objective: Objective: Medicinal herbs offer natural remedies for various ailments because of their comprehensive effects. Scorzonera cinerea L. Sc is an edible wild plant and is used in traditional medicine against various diseases. The purpose of this study was to investigate the immune system effects of S. cinerea radical leaf extract in diabetic rats. Methods: The 5 groups were formed  Control, Diabetic, Sc-Dried, Sc-Frozen, and Acarbose. Adenosine deaminase ADA, xanthine oxidase XO, and myeloperoxidase MPO activities in liver and kidney tissues were analyzed. Hematological parameters were also evaluated. Results: ADA, XO, and MPO activities in both tissues significantly increased in diabetic conditions. However, Sc treatments significantly decreased liver ADA, liver and kidney XO, and liver and kidney MPO activities. There was no significant change in red blood cell RBC parameters. Although platelet PLT count and MPV were raised in the diabetic group, these parameters were reduced with Sc-Dried and Sc-Frozen treatment. While lymphocyte LYM significantly decreased in defense cells in the diabetic group, neutrophil NEU, monocyte MO, and eosinophil EOS elevated. However, a significant decrease was observed in NEU and EOS with Sc treatment. Conclusion: S. cinerea treatment can exert a potential immunoregulatory effect in diabetes. Thus, S. cinerea can be considered as an adjuvant to augment immune system on diabetes.

 Objective: Objective: Medicinal herbs offer natural remedies for various ailments because of their comprehensive effects. Scorzonera cinerea L. Sc is an edible wild plant and is used in traditional medicine against various diseases. The purpose of this study was to investigate the immune system effects of S. cinerea radical leaf extract in diabetic rats. Methods: The 5 groups were formed  Control, Diabetic, Sc-Dried, Sc-Frozen, and Acarbose. Adenosine deaminase ADA, xanthine oxidase XO, and myeloperoxidase MPO activities in liver and kidney tissues were analyzed. Hematological parameters were also evaluated. Results: ADA, XO, and MPO activities in both tissues significantly increased in diabetic conditions. However, Sc treatments significantly decreased liver ADA, liver and kidney XO, and liver and kidney MPO activities. There was no significant change in red blood cell RBC parameters. Although platelet PLT count and MPV were raised in the diabetic group, these parameters were reduced with Sc-Dried and Sc-Frozen treatment. While lymphocyte LYM significantly decreased in defense cells in the diabetic group, neutrophil NEU, monocyte MO, and eosinophil EOS elevated. However, a significant decrease was observed in NEU and EOS with Sc treatment. Conclusion: S. cinerea treatment can exert a potential immunoregulatory effect in diabetes. Thus, S. cinerea can be considered as an adjuvant to augment immune system on diabetes.

Makale detayları

Effects of Scorzonera cinerea on Immune System and Hematological Parameters in Short-Term Hyperglycemia

Yazarlar:

Mehmet Ali Temiz

Yayıncı:

Marmara University

Ana Başlıklar:

Health Care Administration

Dergi:

Clinical and Experimental Health Sciences Vol.13 Issue 1, pp.129-136

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286321

pISSN:

2459-1459

Adenosine deaminase

Hematology

Immunity

myeloperoxidase

Scorzonera cinerea

xanthine oxidase

Sayı

Makale detayları

Effects of Scorzonera cinerea on Immune System and Hematological Parameters in Short-Term Hyperglycemia

Yazarlar: Mehmet Ali Temiz

Yayıncı: Marmara University

Ana Başlıklar: Health Care Administration

Dergi: Clinical and Experimental Health Sciences Vol.13 Issue 1, pp.129-136

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286321

pISSN: 2459-1459

Adenosine deaminase

Hematology

Immunity

myeloperoxidase

Scorzonera cinerea

xanthine oxidase

Sayı

Yazarlar:

Mehmet Ali Temiz

Yayıncı:

Marmara University

Ana Başlıklar:

Health Care Administration

Dergi:

Clinical and Experimental Health Sciences Vol.13 Issue 1, pp.129-136

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286321

pISSN:

2459-1459