Synthesis, crystal structure, and antioxidant properties of novel 1,2,4-triazol-5-ones containing 3,4-dimethoxyphenyl and 3,4-dihydroxyphenyl moiety

Yasemin ÜNVER; Sevgi MEYDANAL; Kemal SANCAK; Dilek ÜNLÜER

doi:https://doi.org/10.3906/sag-1203-100

Makale detayları

Synthesis, crystal structure, and antioxidant properties of novel 1,2,4-triazol-5-ones containing 3,4-dimethoxyphenyl and 3,4-dihydroxyphenyl moiety

Yazarlar:

Yasemin ÜNVER | Sevgi MEYDANAL | Kemal SANCAK | Dilek ÜNLÜER

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2011 Vol.35 Issue 2, pp.265-277

Belge Tipi:

Makale

Yayın Tarihi:

1/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000727874

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/sag-1203-100

Özet:

 

A series of new 4-(3,4-dimethoxyphenethyl)-5-akyl/aryl-2H-  1,2,4-triazol-3(4H)-ones (3a-g) was obtained by the reaction of ethyl  2-(ethoxy)(alkylidene/arylidene)hydrazinecarboxylate (1) and  2-(3,4-dimethoxyphen- yl)ethanamine (2).  Compounds 4a-f and 5 were  synthesized from the reaction of corresponding compounds 3a-f and 3g  with BBr3, respectively.  With elemental analysis, IR, 1H-NMR, and  ^{13C-NMR spectral data, 14 newly synthesized compounds were  characterized.  The structure of compound 3a was inferred through IR,  ^1H- and ^{13}C-NMR, elemental analysis, and X-ray spectral  techniques.  In addition, the newly synthesized chemicals were  screened for their antioxidant properties.  Among the chemicals  tested, 4a, 4c, 4d, 4f, and 5 exhibited the highest degree of  antioxidant activity.

 

A series of new 4-(3,4-dimethoxyphenethyl)-5-akyl/aryl-2H-  1,2,4-triazol-3(4H)-ones (3a-g) was obtained by the reaction of ethyl  2-(ethoxy)(alkylidene/arylidene)hydrazinecarboxylate (1) and  2-(3,4-dimethoxyphen- yl)ethanamine (2).  Compounds 4a-f and 5 were  synthesized from the reaction of corresponding compounds 3a-f and 3g  with BBr3, respectively.  With elemental analysis, IR, 1H-NMR, and  ^{13C-NMR spectral data, 14 newly synthesized compounds were  characterized.  The structure of compound 3a was inferred through IR,  ^1H- and ^{13}C-NMR, elemental analysis, and X-ray spectral  techniques.  In addition, the newly synthesized chemicals were  screened for their antioxidant properties.  Among the chemicals  tested, 4a, 4c, 4d, 4f, and 5 exhibited the highest degree of  antioxidant activity.

Makale detayları

Synthesis, crystal structure, and antioxidant properties of novel 1,2,4-triazol-5-ones containing 3,4-dimethoxyphenyl and 3,4-dihydroxyphenyl moiety

Yazarlar: Yasemin ÜNVER | Sevgi MEYDANAL | Kemal SANCAK | Dilek ÜNLÜER

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2011 Vol.35 Issue 2, pp.265-277

Belge Tipi: Makale

Yayın Tarihi: 1/2011

Belge Dili: İngilizce

Document ID (Org No.): 2000727874

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/sag-1203-100

Sayı

Yazarlar:

Yasemin ÜNVER | Sevgi MEYDANAL | Kemal SANCAK | Dilek ÜNLÜER

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2011 Vol.35 Issue 2, pp.265-277

Belge Tipi:

Makale

Yayın Tarihi:

1/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000727874

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/sag-1203-100