Therapeutic properties of oyster mushroom (P. ostreatus) cultivation on different cellulosic substrates

Mehmet Akyüz; Şule İnci; Sevda Kırbağ

Makale detayları

Therapeutic properties of oyster mushroom (P. ostreatus) cultivation on different cellulosic substrates

Yazarlar:

Mehmet Akyüz | Şule İnci | Sevda Kırbağ

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 1, pp.320-328

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345962

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The objectives of this work were to evaluate the antimicrobial activities, antioxidant in vitro cytotoxicity and DNA damage of Pleurotus ostreatus Jacq. P. Kumm. cultivation on some local cellulosic substrates. It observed to be very active against bacteria except S. mutans and K. pneumonia, yeast and dermatophytes when compared to the control groups 10.0-32.7 mm. It also showed significant antioxidant potential, the highest TAS 0.978 mmolL and TOS 10.51 µmolL values were obtained in M-P 1:1 and W, and also DPPH radical scavenging effects was more effective at 25 mg 74.80 on MS. The methanol extract of P. ostreatus cultured on M-W 2.35 and M-P 1:1 9.74 at 400 μgmL concentration has remarkably decreased the percentage of viability in MDA-MB-231 and A-549 cell lines. However, it has been determined that P. ostreatus does not have a DNA protective effect. These results indicate that P. ostreatus has potent antimicrobial, antioxidant, as well as cytotoxic effects.

 The objectives of this work were to evaluate the antimicrobial activities, antioxidant in vitro cytotoxicity and DNA damage of Pleurotus ostreatus Jacq. P. Kumm. cultivation on some local cellulosic substrates. It observed to be very active against bacteria except S. mutans and K. pneumonia, yeast and dermatophytes when compared to the control groups 10.0-32.7 mm. It also showed significant antioxidant potential, the highest TAS 0.978 mmolL and TOS 10.51 µmolL values were obtained in M-P 1:1 and W, and also DPPH radical scavenging effects was more effective at 25 mg 74.80 on MS. The methanol extract of P. ostreatus cultured on M-W 2.35 and M-P 1:1 9.74 at 400 μgmL concentration has remarkably decreased the percentage of viability in MDA-MB-231 and A-549 cell lines. However, it has been determined that P. ostreatus does not have a DNA protective effect. These results indicate that P. ostreatus has potent antimicrobial, antioxidant, as well as cytotoxic effects.

 The objectives of this work were to evaluate the antimicrobial activities, antioxidant in vitro cytotoxicity and DNA damage of Pleurotus ostreatus Jacq. P. Kumm. cultivation on some local cellulosic substrates. It observed to be very active against bacteria except S. mutans and K. pneumonia, yeast and dermatophytes when compared to the control groups 10.0-32.7 mm. It also showed significant antioxidant potential, the highest TAS 0.978 mmolL and TOS 10.51 µmolL values were obtained in M-P 1:1 and W, and also DPPH radical scavenging effects was more effective at 25 mg 74.80 on MS. The methanol extract of P. ostreatus cultured on M-W 2.35 and M-P 1:1 9.74 at 400 μgmL concentration has remarkably decreased the percentage of viability in MDA-MB-231 and A-549 cell lines. However, it has been determined that P. ostreatus does not have a DNA protective effect. These results indicate that P. ostreatus has potent antimicrobial, antioxidant, as well as cytotoxic effects.

 The objectives of this work were to evaluate the antimicrobial activities, antioxidant in vitro cytotoxicity and DNA damage of Pleurotus ostreatus Jacq. P. Kumm. cultivation on some local cellulosic substrates. It observed to be very active against bacteria except S. mutans and K. pneumonia, yeast and dermatophytes when compared to the control groups 10.0-32.7 mm. It also showed significant antioxidant potential, the highest TAS 0.978 mmolL and TOS 10.51 µmolL values were obtained in M-P 1:1 and W, and also DPPH radical scavenging effects was more effective at 25 mg 74.80 on MS. The methanol extract of P. ostreatus cultured on M-W 2.35 and M-P 1:1 9.74 at 400 μgmL concentration has remarkably decreased the percentage of viability in MDA-MB-231 and A-549 cell lines. However, it has been determined that P. ostreatus does not have a DNA protective effect. These results indicate that P. ostreatus has potent antimicrobial, antioxidant, as well as cytotoxic effects.

Makale detayları

Therapeutic properties of oyster mushroom (P. ostreatus) cultivation on different cellulosic substrates

Yazarlar:

Mehmet Akyüz | Şule İnci | Sevda Kırbağ

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 1, pp.320-328

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345962

pISSN:

2630-6344

P. ostreatus

edible mushroom

medicinal effect

cytotoxicity

DNA damage

Sayı

Makale detayları

Therapeutic properties of oyster mushroom (P. ostreatus) cultivation on different cellulosic substrates

Yazarlar: Mehmet Akyüz | Şule İnci | Sevda Kırbağ

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.27 Issue 1, pp.320-328

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001345962

pISSN: 2630-6344

P. ostreatus

edible mushroom

medicinal effect

cytotoxicity

DNA damage

Sayı

Yazarlar:

Mehmet Akyüz | Şule İnci | Sevda Kırbağ

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.27 Issue 1, pp.320-328

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345962

pISSN:

2630-6344