Asymmetric synthesis of 8-O-4'-neolignan perseal B

Ya-mu XIA; Wei WANG; Ying-lan Guo And Jun-feng LI; Ying-lan GUO; Jun-feng LI

Makale detayları

Asymmetric synthesis of 8-O-4'-neolignan perseal B

Yazarlar:

Ya-mu XIA | Wei WANG | Ying-lan Guo And Jun-feng LI | Ying-lan GUO | Jun-feng LI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 3, pp.375-380

Belge Tipi:

Makale

Yayın Tarihi:

2/2010

Belge Dili:

Türkçe

Document ID (Org No.):

2000728052

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Full details of an enantioselective total synthesis of  8-O-4'-neolignan perseal B are presented for the first time.  The  synthesis was achieved in 8 steps from vanillin and involved the  asymmetric dihydroxylation reaction using AD-mix-a to give the  key intermedium (1S,2S)-1-(4-(benzyloxy)-3-methoxyphenyl)propane-1,2,3-  triol, and the Mitsunobu reaction between phenylpropanoid and vanillin  formed perseal B. The synthetic method of perseal B exhibits a new  route for 8-O-4'-neolignan.

 

Full details of an enantioselective total synthesis of  8-O-4'-neolignan perseal B are presented for the first time.  The  synthesis was achieved in 8 steps from vanillin and involved the  asymmetric dihydroxylation reaction using AD-mix-a to give the  key intermedium (1S,2S)-1-(4-(benzyloxy)-3-methoxyphenyl)propane-1,2,3-  triol, and the Mitsunobu reaction between phenylpropanoid and vanillin  formed perseal B. The synthetic method of perseal B exhibits a new  route for 8-O-4'-neolignan.

Makale detayları

Asymmetric synthesis of 8-O-4'-neolignan perseal B

Yazarlar: Ya-mu XIA | Wei WANG | Ying-lan Guo And Jun-feng LI | Ying-lan GUO | Jun-feng LI

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2010 Vol.34 Issue 3, pp.375-380

Belge Tipi: Makale

Yayın Tarihi: 2/2010

Belge Dili: Türkçe

Document ID (Org No.): 2000728052

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Ya-mu XIA | Wei WANG | Ying-lan Guo And Jun-feng LI | Ying-lan GUO | Jun-feng LI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 3, pp.375-380

Belge Tipi:

Makale

Yayın Tarihi:

2/2010

Belge Dili:

Türkçe

Document ID (Org No.):

2000728052

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527