The Relationship Between Endoscopic Findings and Laboratory Results in Inflammatory Bowel Diseases

Mehtap Şahin

Makale detayları

The Relationship Between Endoscopic Findings and Laboratory Results in Inflammatory Bowel Diseases

Yazarlar:

Mehtap Şahin

Yayıncı:

Hitit University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 2, pp.153-160

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321972

pISSN:

2687-4717

Anahtar kelimeler:

Özet:

 Objective: The aim of this study was to determine the relationship between routine laboratory indicators Including hemoglobin, white blood cells, platelets, erythrocyte sedimentation rate ESR, and C-reactive protein CRP and the extent of endoscopic involvement in individuals with inflammatory bowel disease IBD. Material and Method: The medical records of patients who were diagnosed with Ulcerative Colitis UC and Crohns Disease CD between 2009 and 2015 were retrospectively examined. Endoscopic findings and hemoglobin, white blood cell, platelet, ESR, and CRP values at the time of colonoscopy were analyzed. An exploratory multinomial regression model was created to examine the association of laboratory parameters and endoscopic involvement localization. Results: In UC, a significant decrease in hemoglobin levels was present in cases with extensive colitispancolitis compared to distal type colitis p0.02, while no significant difference was found between left-sided colitis and distal type colitis. Elevated ESR values were notably found in left-sided colitis p0.007 and extensive colitis pancolitis p0.043 compared to distal type colitis. CRP levels were significantly higher in cases with extensive colitispancolitis p0.015. No relationship was identified between laboratory parameters and the endoscopic location of involvement in CD. Conclusion: Although hemoglobin value, ESR and CRP levels are helpful in determining the location of involvement in UC, their effects have not been observed in CD. In addition to these basic laboratory values, other parameters should also be taken into consideration in the evaluation of patients.

 Objective: The aim of this study was to determine the relationship between routine laboratory indicators Including hemoglobin, white blood cells, platelets, erythrocyte sedimentation rate ESR, and C-reactive protein CRP and the extent of endoscopic involvement in individuals with inflammatory bowel disease IBD. Material and Method: The medical records of patients who were diagnosed with Ulcerative Colitis UC and Crohns Disease CD between 2009 and 2015 were retrospectively examined. Endoscopic findings and hemoglobin, white blood cell, platelet, ESR, and CRP values at the time of colonoscopy were analyzed. An exploratory multinomial regression model was created to examine the association of laboratory parameters and endoscopic involvement localization. Results: In UC, a significant decrease in hemoglobin levels was present in cases with extensive colitispancolitis compared to distal type colitis p0.02, while no significant difference was found between left-sided colitis and distal type colitis. Elevated ESR values were notably found in left-sided colitis p0.007 and extensive colitis pancolitis p0.043 compared to distal type colitis. CRP levels were significantly higher in cases with extensive colitispancolitis p0.015. No relationship was identified between laboratory parameters and the endoscopic location of involvement in CD. Conclusion: Although hemoglobin value, ESR and CRP levels are helpful in determining the location of involvement in UC, their effects have not been observed in CD. In addition to these basic laboratory values, other parameters should also be taken into consideration in the evaluation of patients.

 Objective: The aim of this study was to determine the relationship between routine laboratory indicators Including hemoglobin, white blood cells, platelets, erythrocyte sedimentation rate ESR, and C-reactive protein CRP and the extent of endoscopic involvement in individuals with inflammatory bowel disease IBD. Material and Method: The medical records of patients who were diagnosed with Ulcerative Colitis UC and Crohns Disease CD between 2009 and 2015 were retrospectively examined. Endoscopic findings and hemoglobin, white blood cell, platelet, ESR, and CRP values at the time of colonoscopy were analyzed. An exploratory multinomial regression model was created to examine the association of laboratory parameters and endoscopic involvement localization. Results: In UC, a significant decrease in hemoglobin levels was present in cases with extensive colitispancolitis compared to distal type colitis p0.02, while no significant difference was found between left-sided colitis and distal type colitis. Elevated ESR values were notably found in left-sided colitis p0.007 and extensive colitis pancolitis p0.043 compared to distal type colitis. CRP levels were significantly higher in cases with extensive colitispancolitis p0.015. No relationship was identified between laboratory parameters and the endoscopic location of involvement in CD. Conclusion: Although hemoglobin value, ESR and CRP levels are helpful in determining the location of involvement in UC, their effects have not been observed in CD. In addition to these basic laboratory values, other parameters should also be taken into consideration in the evaluation of patients.

 Amaç: Bu çalışmanın amacı, inflamatuvar barsak hastalığı İBH olan olgularda rutin laboratuvar bulguları hemoglobin, beyaz küre, trombosit, eritrosit sedimentasyon hızı ESH, C-reaktif protein CRP ile endoskopik tutulum alanları arasındaki ilişkiyi belirlemektir. Gereç ve Yöntem: 2009-2015 yılları arasında Ülseratif Kolit ÜK ve Crohn Hastalığı CH tanısı alan hastaların tıbbi kayıtları geriye dönük olarak incelendi. Endoskopik bulgular ile kolonoskopi sırasındaki hemoglobin, beyaz kan hücresi, trombosit, ESR ve CRP değerleri kaydedildi. Laboratuvar parametreleri ile endoskopik tutulum lokalizasyonu arasındaki ilişkiyi incelemek için multinominal lojistik regresyon modeli oluşturuldu. Bulgular: ÜKte; ekstensif kolitpankolit tutulumunda distal tip kolite göre hemoglobin değerinde anlamlı derecede düşüş saptanmışken p0.02, sol taraf kolitiyle distal tip kolit arasında anlamlı fark saptanmamıştır. Sol taraf koliti p0,007 ve ekstensif kolitpankolit p0.043 tutulumunda distal tip kolite göre ESH değerleri belirgin yüksek bulunmuştur. CRP değeri sadece ekstensif kolitpankolit tutulumunda anlamlı yüksek çıkmıştır p0.015. CH için laboratuvar parametreleri ile tutulum yerleri arasında herhangi bir ilişki bulunamamıştır. Sonuç: ÜKte hemoglobin değeri, ESR ve CRP düzeyleri tutulumun yerini belirlemede yardımcı olsa da CHde etkileri görülmemiştir. Hastaların değerlendirilmesinde bu temel laboratuvar değerlerinin yanı sıra diğer parametrelerin de dikkate alınması gerekir.

Makale detayları

The Relationship Between Endoscopic Findings and Laboratory Results in Inflammatory Bowel Diseases

Yazarlar:

Mehtap Şahin

Yayıncı:

Hitit University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 2, pp.153-160

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321972

pISSN:

2687-4717

C-reactive protein

Crohn

Erythrocyte Sedimentation Rate

Ulcerative ColitisC-reaktif protein

Crohn Hastalığı

eritrosit sedimentasyon hızı

Ülseratif kolit

Sayı

Makale detayları

Yazarlar: Mehtap Şahin

Yayıncı: Hitit University

Ana Başlıklar: Gastroenteroloji ve Hepatoloji

Dergi: Hitit Medical Journal Vol.6 Issue 2, pp.153-160

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001321972

pISSN: 2687-4717

Sayı

Yazarlar:

Mehtap Şahin

Yayıncı:

Hitit University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Hitit Medical Journal Vol.6 Issue 2, pp.153-160

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321972

pISSN:

2687-4717