Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean

Anıl Erturk; Gulay Gokce; Nergis Kender Erturk

Makale detayları

Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean

Yazarlar:

Anıl Erturk | Gulay Gokce | Nergis Kender Erturk

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology

Dergi:

The European Research Journal Vol.9 Issue 5, pp.1048-1055

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288122

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section CS on isthmocele formation. Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation. Results: Of the 106 patients, 31 29.2 were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele 42.58  8.77 vs. 38.42  9.50 minutes, p  0.03. The neutrophil-to-lymphocyte ratio NLR was higher and platelet-to-lymphocyte ratio PLR was lower in the isthmocele group  p  0.001. Logistic regression analysis revealed that, NLR OR odds ratio: 0.23, 95 CI confidence interval: 0.117- 0.473, p  0.001 and PLR OR: 1.05, 95 CI: 1.027-1.078, p  0.001 were identified as independent predictors for isthmocele formation after planned CS. Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.

 Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section CS on isthmocele formation. Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation. Results: Of the 106 patients, 31 29.2 were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele 42.58  8.77 vs. 38.42  9.50 minutes, p  0.03. The neutrophil-to-lymphocyte ratio NLR was higher and platelet-to-lymphocyte ratio PLR was lower in the isthmocele group  p  0.001. Logistic regression analysis revealed that, NLR OR odds ratio: 0.23, 95 CI confidence interval: 0.117- 0.473, p  0.001 and PLR OR: 1.05, 95 CI: 1.027-1.078, p  0.001 were identified as independent predictors for isthmocele formation after planned CS. Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.

 Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section CS on isthmocele formation. Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation. Results: Of the 106 patients, 31 29.2 were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele 42.58  8.77 vs. 38.42  9.50 minutes, p  0.03. The neutrophil-to-lymphocyte ratio NLR was higher and platelet-to-lymphocyte ratio PLR was lower in the isthmocele group  p  0.001. Logistic regression analysis revealed that, NLR OR odds ratio: 0.23, 95 CI confidence interval: 0.117- 0.473, p  0.001 and PLR OR: 1.05, 95 CI: 1.027-1.078, p  0.001 were identified as independent predictors for isthmocele formation after planned CS. Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.

 Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section CS on isthmocele formation. Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation. Results: Of the 106 patients, 31 29.2 were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele 42.58  8.77 vs. 38.42  9.50 minutes, p  0.03. The neutrophil-to-lymphocyte ratio NLR was higher and platelet-to-lymphocyte ratio PLR was lower in the isthmocele group  p  0.001. Logistic regression analysis revealed that, NLR OR odds ratio: 0.23, 95 CI confidence interval: 0.117- 0.473, p  0.001 and PLR OR: 1.05, 95 CI: 1.027-1.078, p  0.001 were identified as independent predictors for isthmocele formation after planned CS. Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.

Makale detayları

Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean

Yazarlar:

Anıl Erturk | Gulay Gokce | Nergis Kender Erturk

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology

Dergi:

The European Research Journal Vol.9 Issue 5, pp.1048-1055

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288122

pISSN:

2149-3189

Cesarean scar defect

isthmocele

neutrophil-to-lymphocyte ratio

platelet-to-lymphocyte ratio

Sayı

Makale detayları

Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean

Yazarlar: Anıl Erturk | Gulay Gokce | Nergis Kender Erturk

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Obstetrics and Gynaecology

Dergi: The European Research Journal Vol.9 Issue 5, pp.1048-1055

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001288122

pISSN: 2149-3189

Cesarean scar defect

isthmocele

neutrophil-to-lymphocyte ratio

platelet-to-lymphocyte ratio

Sayı

Yazarlar:

Anıl Erturk | Gulay Gokce | Nergis Kender Erturk

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology

Dergi:

The European Research Journal Vol.9 Issue 5, pp.1048-1055

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288122

pISSN:

2149-3189