Calculation of the Choroidal Vascularity Index and Tissue Distribution Indexes in Different Retinal and Choroidal Regions by Employing Digital Image Processing Techniques in Optical Coherence Tomography Images

Onur İnam; Deniz Somer; Güner Üney; Abdullah Soylu

Makale detayları

Calculation of the Choroidal Vascularity Index and Tissue Distribution Indexes in Different Retinal and Choroidal Regions by Employing Digital Image Processing Techniques in Optical Coherence Tomography Images

Yazarlar:

Onur İnam | Deniz Somer | Güner Üney | Abdullah Soylu

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.33 Issue 6, pp.785-795

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001307941

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 Objective: In this study, it is aimed to investigate the optical coherence tomography images of healthy subjects for various parameters and tissue distribution indexes. Materials and Methods: 100 eyes of 50 healthy cases optical coherence tomography OCT images have been employed for analysis. Total retinal area TRA, dark retinal area DRA, light retinal area LRA, dark area percent DAP and light area percent LAP as retinal measurements; total choroidal area TCA, luminal choroidal area LCA, stromal choroidal area SCA, luminal area percent or choroidal vascularity index CVI and stromal area percent SAP as choroidal measurements have been investigated for vertical and horizontal OCT scans. 6500 µm of the total retinal and choroidal area have been binarized and analyzed in 100 µm intervals and further divided into three main parts: inner, middle, and outer. Results: CVI value for the entire vertical scan is 69.22.6, whereas the entire horizontal scan is 70.12.7 p0.019. Entire inner part CVI of the vertical scans are calculated as 74.54.6 and in horizontal scans as 74.85.0 p0.678. Vertical CVI of the entire middle part has higher values as 67.2  3.9 than the horizontal scans as 66.04.1 p0.025. This was conversely recorded at the entire outer part, which the vertical CVI value is 66.64.3 and horizontal CVI value is 70.34.7 p0.001. Although there was no statistically significant difference for any of the TRA comparisons for entire region of interest, entire inner, entire middle and entire outer parts between vertical and horizontal scans p0.386, p0.422, p0.309 and p0.352 respectively, vertical TCA measurements were significantly higher than the horizontal scans p0.010, p0.013, p0.012 and p0.008, respectively. Conclusion: CVI and other parameters and tissue distribution indexes could be a valuable tool for differentiating and evaluating the retinal and choroidal conditions in different scan regions.

 Objective: In this study, it is aimed to investigate the optical coherence tomography images of healthy subjects for various parameters and tissue distribution indexes. Materials and Methods: 100 eyes of 50 healthy cases optical coherence tomography OCT images have been employed for analysis. Total retinal area TRA, dark retinal area DRA, light retinal area LRA, dark area percent DAP and light area percent LAP as retinal measurements; total choroidal area TCA, luminal choroidal area LCA, stromal choroidal area SCA, luminal area percent or choroidal vascularity index CVI and stromal area percent SAP as choroidal measurements have been investigated for vertical and horizontal OCT scans. 6500 µm of the total retinal and choroidal area have been binarized and analyzed in 100 µm intervals and further divided into three main parts: inner, middle, and outer. Results: CVI value for the entire vertical scan is 69.22.6, whereas the entire horizontal scan is 70.12.7 p0.019. Entire inner part CVI of the vertical scans are calculated as 74.54.6 and in horizontal scans as 74.85.0 p0.678. Vertical CVI of the entire middle part has higher values as 67.2  3.9 than the horizontal scans as 66.04.1 p0.025. This was conversely recorded at the entire outer part, which the vertical CVI value is 66.64.3 and horizontal CVI value is 70.34.7 p0.001. Although there was no statistically significant difference for any of the TRA comparisons for entire region of interest, entire inner, entire middle and entire outer parts between vertical and horizontal scans p0.386, p0.422, p0.309 and p0.352 respectively, vertical TCA measurements were significantly higher than the horizontal scans p0.010, p0.013, p0.012 and p0.008, respectively. Conclusion: CVI and other parameters and tissue distribution indexes could be a valuable tool for differentiating and evaluating the retinal and choroidal conditions in different scan regions.

 Objective: In this study, it is aimed to investigate the optical coherence tomography images of healthy subjects for various parameters and tissue distribution indexes. Materials and Methods: 100 eyes of 50 healthy cases optical coherence tomography OCT images have been employed for analysis. Total retinal area TRA, dark retinal area DRA, light retinal area LRA, dark area percent DAP and light area percent LAP as retinal measurements; total choroidal area TCA, luminal choroidal area LCA, stromal choroidal area SCA, luminal area percent or choroidal vascularity index CVI and stromal area percent SAP as choroidal measurements have been investigated for vertical and horizontal OCT scans. 6500 µm of the total retinal and choroidal area have been binarized and analyzed in 100 µm intervals and further divided into three main parts: inner, middle, and outer. Results: CVI value for the entire vertical scan is 69.22.6, whereas the entire horizontal scan is 70.12.7 p0.019. Entire inner part CVI of the vertical scans are calculated as 74.54.6 and in horizontal scans as 74.85.0 p0.678. Vertical CVI of the entire middle part has higher values as 67.2  3.9 than the horizontal scans as 66.04.1 p0.025. This was conversely recorded at the entire outer part, which the vertical CVI value is 66.64.3 and horizontal CVI value is 70.34.7 p0.001. Although there was no statistically significant difference for any of the TRA comparisons for entire region of interest, entire inner, entire middle and entire outer parts between vertical and horizontal scans p0.386, p0.422, p0.309 and p0.352 respectively, vertical TCA measurements were significantly higher than the horizontal scans p0.010, p0.013, p0.012 and p0.008, respectively. Conclusion: CVI and other parameters and tissue distribution indexes could be a valuable tool for differentiating and evaluating the retinal and choroidal conditions in different scan regions.

 Amaç: Bu çalışmada, sağlıklı bireylerin optik koherens tomografi görüntülerinin çeşitli parametreler ve doku dağılım indeksleri açısından incelenmesi amaçlanmaktadır. Gereç ve Yöntemler: 50 sağlıklı bireyin 100 gözünün optik koherens tomografi OKT görüntüleri analiz için kullanılmıştır. Toplam retina alanı TRA, karanlık retina alanı DRA, aydınlık retina alanı LRA, karanlık alan yüzdesi DAP ve aydınlık alan yüzdesi LAP gibi retina ölçümleri; toplam koroid alanı TCA, lüminal koroidal alan LCA, stromal koroidal alan SCA, lüminal alan yüzdesi veya koroidal vaskülerite indeksi CVI ve stromal alan yüzdesi SAP gibi koroidal ölçümler, dikey ve yatay OKT taramaları için incelendi. Toplam retinal ve koroidal alanın 6500 µmsi 100 µm aralıklarla binarize hale getirilip analiz edildi ve daha sonra iç, orta ve dış olmak üzere üç ana bölüme ayrıldı. Bulgular: Tüm dikey tarama CVI değeri 69.22.6 iken, tüm yatay tarama için bu değer 70.12.7 olarak hesaplandı p0.019. Dikey taramalar için tüm iç bölüm CVI değeri 74.54.6 ve yatay taramalar için 74.85.0 olarak hesaplandı p0.678. Tüm orta bölüm dikey CVI değeri 67.2  3.9 iken yatay taramalarda 66.04.1 olarak bulundu p0.025. Bu durum tüm dış bölüm için tersiydi; dikey CVI değeri 66.64.3 iken yatay CVI değeri 70.34.7 olarak bulundu p0.001. TRA karşılaştırmalarının hiçbirinde, tüm bölüm, iç bölüm, orta bölüm ve dış bölüm için dikey ve yatay taramalar arasında istatistiksel olarak anlamlı fark bulunmadı sırasıyla p0.386, p0.422, p0.309 ve p0.352. Ancak dikey TCA ölçümleri, yatay taramalara göre istatistiksel olarak anlamlı şekilde yüksek bulundu sırasıyla p0.010, p0.013, p0.012 ve p0.008. Sonuç: CVI, diğer parametreler ve doku dağılım indeksleri, farklı tarama bölgelerinde retinal ve koroidal durumları ayırt etmek ve değerlendirmek için değerli bir araç olabilir.

Makale detayları

Calculation of the Choroidal Vascularity Index and Tissue Distribution Indexes in Different Retinal and Choroidal Regions by Employing Digital Image Processing Techniques in Optical Coherence Tomography Images

Yazarlar:

Onur İnam | Deniz Somer | Güner Üney | Abdullah Soylu

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.33 Issue 6, pp.785-795

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001307941

pISSN:

2602-3741

Biophysics

Image Processing

Optical Coherence Tomography

Retina

ChoroidBiyofizik

Görüntü İşleme

optik koherens tomografi

Retina

Koroid

Sayı

Makale detayları

Yazarlar: Onur İnam | Deniz Somer | Güner Üney | Abdullah Soylu

Yayıncı: Selcuk University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Genel Tıp Dergisi Vol.33 Issue 6, pp.785-795

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001307941

pISSN: 2602-3741

Sayı

Yazarlar:

Onur İnam | Deniz Somer | Güner Üney | Abdullah Soylu

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.33 Issue 6, pp.785-795

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001307941

pISSN:

2602-3741