EFFECTS OF OCCUPATIONAL EXPOSURE TO IONIZING RADIATION ON OXIDATIVE STRESS AND INFLAMMATORY MARKERS IN HEALTHCARE WORKERS OF A UNIVERSITY HOSPITAL IN KONYA, TURKEY

Zehra ARDIÇ; Tahir Kemal ŞAHİN; Mehmet UYAR; Hasan KÜÇÜKKENDİRCİ; İbrahim KILINC; Elif Nur YILDIRIM ÖZTÜRK

doi:https://doi.org/10.37212/jcnos.1012615

Makale detayları

EFFECTS OF OCCUPATIONAL EXPOSURE TO IONIZING RADIATION ON OXIDATIVE STRESS AND INFLAMMATORY MARKERS IN HEALTHCARE WORKERS OF A UNIVERSITY HOSPITAL IN KONYA, TURKEY

Yazarlar:

Zehra ARDIÇ | Tahir Kemal ŞAHİN | Mehmet UYAR | Hasan KÜÇÜKKENDİRCİ | İbrahim KILINC | Elif Nur YILDIRIM ÖZTÜRK

Yayıncı:

Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Ana Başlıklar:

Hastalıklar

Dergi:

Journal of Cellular Neuroscience and Oxidative Stress 2021 Vol.13 Issue 2, pp.994-1003

Belge Tipi:

Makale

Yayın Tarihi:

2/2022

Belge Dili:

İngilizce

Document ID (Org No.):

2000708677

Sıklık:

Üç Yıllık

eISSN:

2149-7222

DOI:

https://doi.org/10.37212/jcnos.1012615

Özet:

 

OBJECTIVE Ionizing radiation (IR) has a wide area of use and its effects on human health have been discussed since its discovery. This study aimed to show oxidative stress and inflammation due to ionizing radiation exposure based on biomarkers in healthcare workers.
METHOD This study was conducted with 172 people, who were exposed to IR in the work environment and those who did not have exposure to radiation. In this cross-sectional study, a data collection form was used to obtain data from the participants. In addition, 6 ml of blood was taken to measure their tumor necrosis factor (TNF)-alpha, total oxidant status (TOS), interleukin (IL)-10 and total antioxidant status (TAS) levels, and calculate their oxidative stress index (OSI) values.
RESULTS In the ionizing radiation group, 50% of the participants were men, the mean age was 35.91±7.07 years, and the mean duration of employment was 9.80±7.1 years. The TOS, OSI, TNF-α and IL-10 values were higher and TAS was lower in the ionizing radiation group compared to the participants without exposure to ionizing radiation. Gender, smoking, alcohol use, presence of chronic diseases, regular medication use, antioxidant supplement use, and exposure to radiation for medical diagnosis and treatment within the last year did not affect oxidative stress and inflammation in the radiation workers. The cut-off values of the TOS, TAS, OSI, TNF-α and IL-10 biomarkers were also determined.
CONCLUSION Occupational low-dose long-term exposure to ionizing radiation was found to increase oxidative stress and inflammation.

Makale detayları

EFFECTS OF OCCUPATIONAL EXPOSURE TO IONIZING RADIATION ON OXIDATIVE STRESS AND INFLAMMATORY MARKERS IN HEALTHCARE WORKERS OF A UNIVERSITY HOSPITAL IN KONYA, TURKEY

Yazarlar: Zehra ARDIÇ | Tahir Kemal ŞAHİN | Mehmet UYAR | Hasan KÜÇÜKKENDİRCİ | İbrahim KILINC | Elif Nur YILDIRIM ÖZTÜRK

Yayıncı: Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Ana Başlıklar: Hastalıklar

Dergi: Journal of Cellular Neuroscience and Oxidative Stress 2021 Vol.13 Issue 2, pp.994-1003

Belge Tipi: Makale

Yayın Tarihi: 2/2022

Belge Dili: İngilizce

Document ID (Org No.): 2000708677

Sıklık: Üç Yıllık

eISSN: 2149-7222

DOI: https://doi.org/10.37212/jcnos.1012615

Sayı

Yazarlar:

Zehra ARDIÇ | Tahir Kemal ŞAHİN | Mehmet UYAR | Hasan KÜÇÜKKENDİRCİ | İbrahim KILINC | Elif Nur YILDIRIM ÖZTÜRK

Yayıncı:

Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Ana Başlıklar:

Hastalıklar

Dergi:

Journal of Cellular Neuroscience and Oxidative Stress 2021 Vol.13 Issue 2, pp.994-1003

Belge Tipi:

Makale

Yayın Tarihi:

2/2022

Belge Dili:

İngilizce

Document ID (Org No.):

2000708677

Sıklık:

Üç Yıllık

eISSN:

2149-7222

DOI:

https://doi.org/10.37212/jcnos.1012615