Mean Platelet Volume as a New Inflammatory Marker in Acute Pancreatitis and Its Relation to C-Reactive Protein and Ranson’s Score on Admission

Baris Karagün; Tayyibe Saler

Makale detayları

Mean Platelet Volume as a New Inflammatory Marker in Acute Pancreatitis and Its Relation to C-Reactive Protein and Ranson’s Score on Admission

Yazarlar:

Baris Karagün | Tayyibe Saler

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 1, pp.9-13

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288834

pISSN:

2822-4302

Anahtar kelimeler:

Özet:

 Aim: The studys aim is to evaluate mean platelet volume MPV as a marker of inflammation in patients with acute pancreatitis AP and to analyse the relationships among MPV, CRP C-reactive protein and Ransons score. Material and Methods: In this study, 119 patients with AP mean age 53.8  18.0 years and 88 healthy control group mean age 53.1  6.8 years were enrolled. Among the patients with AP, 75 were classified as having biliary AP, and 44 were classified as having nonbiliary AP. All patients demographic data, clinical and laboratory findings and Ransons scores were examined from the hospitals database. Results: MPV was significantly lower among patients with AP than among the control group p  0.001. CRP was significantly higher among patients with AP than among the control group p 0.001. The difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When we compared MPV based on patients lengths of hospital stay, there was no significant difference. In correlation analysis, there was no correlation among CRP, Ransons score and serum MPV levels. Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like other inflammation markers, MPV might be a useful marker for AP diagnosis.

 Aim: The studys aim is to evaluate mean platelet volume MPV as a marker of inflammation in patients with acute pancreatitis AP and to analyse the relationships among MPV, CRP C-reactive protein and Ransons score. Material and Methods: In this study, 119 patients with AP mean age 53.8  18.0 years and 88 healthy control group mean age 53.1  6.8 years were enrolled. Among the patients with AP, 75 were classified as having biliary AP, and 44 were classified as having nonbiliary AP. All patients demographic data, clinical and laboratory findings and Ransons scores were examined from the hospitals database. Results: MPV was significantly lower among patients with AP than among the control group p  0.001. CRP was significantly higher among patients with AP than among the control group p 0.001. The difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When we compared MPV based on patients lengths of hospital stay, there was no significant difference. In correlation analysis, there was no correlation among CRP, Ransons score and serum MPV levels. Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like other inflammation markers, MPV might be a useful marker for AP diagnosis.

 Aim: The studys aim is to evaluate mean platelet volume MPV as a marker of inflammation in patients with acute pancreatitis AP and to analyse the relationships among MPV, CRP C-reactive protein and Ransons score. Material and Methods: In this study, 119 patients with AP mean age 53.8  18.0 years and 88 healthy control group mean age 53.1  6.8 years were enrolled. Among the patients with AP, 75 were classified as having biliary AP, and 44 were classified as having nonbiliary AP. All patients demographic data, clinical and laboratory findings and Ransons scores were examined from the hospitals database. Results: MPV was significantly lower among patients with AP than among the control group p  0.001. CRP was significantly higher among patients with AP than among the control group p 0.001. The difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When we compared MPV based on patients lengths of hospital stay, there was no significant difference. In correlation analysis, there was no correlation among CRP, Ransons score and serum MPV levels. Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like other inflammation markers, MPV might be a useful marker for AP diagnosis.

 Amaç: Bu çalışmada akut pankreatitli AP hastalarda inflamasyon belirteci olarak ortalama trombosit hacmini MPV değerlendirmek ve MPV, CRP C-reactive protein ile Ranson skoru arasındaki ilişkiyi inceleme amaçlandı. Gereç ve Yöntemler: Bu çalışmaya APli 119 hasta ortalama yaş 53.8  18.0 yıl ve 88 sağlıklı kontrol grubu ortalama yaş 53.1  6.8 yıl alındı. APli hastalardan 75i biliyer AP, 44ü biliyer olmayan AP olarak sınıflandırıldı. Tüm hastaların demografik verileri, klinik ve laboratuvar bulguları ve Ranson skorları hastanenin veri tabanından incelendi. Bulgular: MPV, APli hastalarda kontrol grubuna göre anlamlı olarak daha düşüktü p  0.001. APli hastalarda CRP, kontrol grubuna göre anlamlı olarak daha yüksekti p  0.001. Biliyer ve biliyer olmayan AP grup arasındaki MPV farkı istatistiksel olarak anlamlı bulunmadı. Hastaların hastanede kalış sürelerine göre MPV değerlerini karşılaştırdığımızda anlamlı bir fark yoktu. Korelasyon analizinde CRP, Ranson skoru ve serum MPV seviyeleri arasında korelasyon yoktu. Sonuç: AP grubunda MPV düzeylerinin sağlıklı kontrollere göre daha düşük olduğunu gözlemledik. Bu nedenle, diğer inflamasyon belirteçleri gibi MPV de AP tanısı için yararlı bir belirteç olabilir.

Makale detayları

Mean Platelet Volume as a New Inflammatory Marker in Acute Pancreatitis and Its Relation to C-Reactive Protein and Ranson’s Score on Admission

Yazarlar:

Baris Karagün | Tayyibe Saler

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 1, pp.9-13

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288834

pISSN:

2822-4302

Acute pancreatitis

Mean platelet volume

InflammationAkut pankreatit

Ortalama trombosit hacmi

inflamasyon

Sayı

Makale detayları

Mean Platelet Volume as a New Inflammatory Marker in Acute Pancreatitis and Its Relation to C-Reactive Protein and Ranson’s Score on Admission

Yazarlar: Baris Karagün | Tayyibe Saler

Yayıncı: Zonguldak Bulent Ecevit University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Batı Karadeniz Tıp Dergisi Vol.7 Issue 1, pp.9-13

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001288834

pISSN: 2822-4302

Acute pancreatitis

Mean platelet volume

InflammationAkut pankreatit

Ortalama trombosit hacmi

inflamasyon

Sayı

Yazarlar:

Baris Karagün | Tayyibe Saler

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 1, pp.9-13

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001288834

pISSN:

2822-4302