SİRNAK PROVİNCE FİRST TRİMESTER PRENATAL SCREENİNG TEST CURRENT MEDİAN VALUES

Veysel Tahiroğlu; Naci Ömer Alayunt; Erkam Coşkun

Makale detayları

SİRNAK PROVİNCE FİRST TRİMESTER PRENATAL SCREENİNG TEST CURRENT MEDİAN VALUES

Yazarlar:

Veysel Tahiroğlu | Naci Ömer Alayunt | Erkam Coşkun

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri | Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 2, pp.128-132

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001291848

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: We aimed to compare the current median values of hormone levels used in screening tests performed during the first trimester in pregnant women in Şırnak with the medians of standard software used in hormone devices and to reveal the differences between them. Materials and Methods: In the study, the data of 301 pregnant women who applied to the hospital in Şırnak province between 01052021 and 01052022 were used by pulling prenatal dual screening test measurements from the hospital database after the hospital permission and ethics committee approval were obtained. The MoM levels found according to the median values calculated by the device software and the multiples of the medians MoM calculated according to the weekly median levels entered in the program were compared. Results: Current median levels of free β-HCG were found to be statistically significantly different and lower than those used in screening tests at 11, 12, and 13 weeks of gestation p0.01. Current median levels of PAPP-A were statistically significantly different from the software median levels of 11 and 12 weeks of gestation p0.01. Free β-HCG and PAPP-A Current MoM averages were statistically significantly different and lower than software MoM levels in both p0.01. Conclusion: In this study, it was discussed that comparative data using the current median and local levels of the calculations made to reveal the risk levels of risky pregnancies would also increase the importance and performance of prenatal screening tests.

 Purpose: We aimed to compare the current median values of hormone levels used in screening tests performed during the first trimester in pregnant women in Şırnak with the medians of standard software used in hormone devices and to reveal the differences between them. Materials and Methods: In the study, the data of 301 pregnant women who applied to the hospital in Şırnak province between 01052021 and 01052022 were used by pulling prenatal dual screening test measurements from the hospital database after the hospital permission and ethics committee approval were obtained. The MoM levels found according to the median values calculated by the device software and the multiples of the medians MoM calculated according to the weekly median levels entered in the program were compared. Results: Current median levels of free β-HCG were found to be statistically significantly different and lower than those used in screening tests at 11, 12, and 13 weeks of gestation p0.01. Current median levels of PAPP-A were statistically significantly different from the software median levels of 11 and 12 weeks of gestation p0.01. Free β-HCG and PAPP-A Current MoM averages were statistically significantly different and lower than software MoM levels in both p0.01. Conclusion: In this study, it was discussed that comparative data using the current median and local levels of the calculations made to reveal the risk levels of risky pregnancies would also increase the importance and performance of prenatal screening tests.

 Purpose: We aimed to compare the current median values of hormone levels used in screening tests performed during the first trimester in pregnant women in Şırnak with the medians of standard software used in hormone devices and to reveal the differences between them. Materials and Methods: In the study, the data of 301 pregnant women who applied to the hospital in Şırnak province between 01052021 and 01052022 were used by pulling prenatal dual screening test measurements from the hospital database after the hospital permission and ethics committee approval were obtained. The MoM levels found according to the median values calculated by the device software and the multiples of the medians MoM calculated according to the weekly median levels entered in the program were compared. Results: Current median levels of free β-HCG were found to be statistically significantly different and lower than those used in screening tests at 11, 12, and 13 weeks of gestation p0.01. Current median levels of PAPP-A were statistically significantly different from the software median levels of 11 and 12 weeks of gestation p0.01. Free β-HCG and PAPP-A Current MoM averages were statistically significantly different and lower than software MoM levels in both p0.01. Conclusion: In this study, it was discussed that comparative data using the current median and local levels of the calculations made to reveal the risk levels of risky pregnancies would also increase the importance and performance of prenatal screening tests.

 Amaç: Şırnakta yaşayan gebelerde birinci trimester dönemi içerisinde yapılan tarama testlerinde kullanılan hormon düzeylerinin güncel medyan değerlerinin, hormon cihazlarında kullanılan standart yazılımların medyanları ile mukayese edilerek aralarındaki farklılıkları ortaya konması amaçlandı. Araçlar ve Yöntem: Çalışmada hastane izin ve etik kurul onayı alındıktan sonra 01052021-01052022 tarihleri arasında Şırnak ilinde hastaneye başvuran 301 gebenin verileri prenatal ikili tarama testi ölçümleri hastane veri tabanından çekilerek kullanılmıştır. Cihaz yazılımı tarafından hesaplanan medyan değerlerine göre bulunan MoM düzeyleri ile programa girilen haftalık medyan düzeylerine göre hesaplanmış medyanların katları MoM karşılaştırılmıştır. Bulgular: Güncel medyan düzeyleri, free β-HCGnin 11. 12. ve 13. gebelik haftalarının tarama testlerinde kullanılan medyan düzeylerinden istatistiksel olarak anlamlı şekilde düşük seviyelerde bulunmuştur p0.01. Güncel medyan düzeyleri, PAPP-Anın 11 ve 12. gebelik haftalarının yazılım medyan düzeylerinden istatistiksel olarak anlamlı şekilde yüksek seviyelerde bulunmuştur p0.01. Free β-HCG ve PAPP-A Güncel MoM ortalamaları her ikisinde de yazılım MoM düzeylerinden istatistiksel olarak anlamlı şekilde düşük düzeylerde bulunmuştur p0.01. Sonuç: Bu çalışmada riskli gebeliklerin risk düzeylerinin ortaya koyulması için yapılan hesaplamaların güncel medyan ve yerel düzeyleri kullanılarak yapılan karşılaştırmalı verilerin de prenatal dönem tarama testlerinin önemini ve performansını artıracağı üzerine tartışılmıştır.

Makale detayları

SİRNAK PROVİNCE FİRST TRİMESTER PRENATAL SCREENİNG TEST CURRENT MEDİAN VALUES

Yazarlar:

Veysel Tahiroğlu | Naci Ömer Alayunt | Erkam Coşkun

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri | Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 2, pp.128-132

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001291848

pISSN:

2619-9203

hCG

PAPP-A

Median value

Prenatal diagnosis

Dual screening testhCG

PAPP-A

Medyan değer

Prenatal tanı

İkili tarama testi

Sayı

Makale detayları

Yazarlar: Veysel Tahiroğlu | Naci Ömer Alayunt | Erkam Coşkun

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Tıp Bilimleri | Klinik Tıp Bilimleri (Diğer)

Dergi: Ahi Evran Tıp Dergisi Vol.7 Issue 2, pp.128-132

Belge Tipi: Makale

Yayın Tarihi: 7/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001291848

pISSN: 2619-9203

Sayı

Yazarlar:

Veysel Tahiroğlu | Naci Ömer Alayunt | Erkam Coşkun

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri | Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 2, pp.128-132

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001291848

pISSN:

2619-9203