Evaluation of the Systemic Immune-Inflammatory Index (SII) and NAPLES Score (NS) in Patients with Non-ST-Elevation Myocardial Infarction (NSTEMI)

Mesut Gitmez

Makale detayları

Evaluation of the Systemic Immune-Inflammatory Index (SII) and NAPLES Score (NS) in Patients with Non-ST-Elevation Myocardial Infarction (NSTEMI)

Yazarlar:

Mesut Gitmez

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.199-206

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319480

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Objective: Non-ST elevation myocardial infarction NSTEMI is the most common type of acute coronary syndrome and has a poor prognosis. The SII and NS are derived from blood cell counts and reflects the balance between inherited and acquired immunity and the association between the immune system and endothelial dysfunction. This study aimed to compare the prognostic value of two novel inflammatory biomarkers, the systemic immune-inflammatory index SII and the Naples score NS, with that of other inflammatory markers and risk scores in patients with NSTEMI. Methods: This was a retrospective cohort analysis of 50 NSTEMI patients and 50 controls matched by age and sex who were admitted to our hospital. We calculated the SII and NS scores and other ratios, indices, and risk scores for each patient. We used Pearsons correlation coefficient and receiver operating characteristic ROC analysis to examine the correlations and predictive values of the SII index, NS score, and other biometric markers and risk scores. Results: The SII and NS were significantly greater in the NSTEMI group than in the control group. They had strong positive correlations with the NLR, MHR, PLR, and TCHDL ratio, and moderate positive correlations with TIMI and HEART scores r0.3, p0.01 for both. The SII and NS also had higher AUC values than other biometric markers and risk scores p0.05 for both. Conclusions: The SII and NS are inexpensive, widely available and easy to measure markers that may have utility for cardiac risk stratification in NSTEMI patients.

 Objective: Non-ST elevation myocardial infarction NSTEMI is the most common type of acute coronary syndrome and has a poor prognosis. The SII and NS are derived from blood cell counts and reflects the balance between inherited and acquired immunity and the association between the immune system and endothelial dysfunction. This study aimed to compare the prognostic value of two novel inflammatory biomarkers, the systemic immune-inflammatory index SII and the Naples score NS, with that of other inflammatory markers and risk scores in patients with NSTEMI. Methods: This was a retrospective cohort analysis of 50 NSTEMI patients and 50 controls matched by age and sex who were admitted to our hospital. We calculated the SII and NS scores and other ratios, indices, and risk scores for each patient. We used Pearsons correlation coefficient and receiver operating characteristic ROC analysis to examine the correlations and predictive values of the SII index, NS score, and other biometric markers and risk scores. Results: The SII and NS were significantly greater in the NSTEMI group than in the control group. They had strong positive correlations with the NLR, MHR, PLR, and TCHDL ratio, and moderate positive correlations with TIMI and HEART scores r0.3, p0.01 for both. The SII and NS also had higher AUC values than other biometric markers and risk scores p0.05 for both. Conclusions: The SII and NS are inexpensive, widely available and easy to measure markers that may have utility for cardiac risk stratification in NSTEMI patients.

 Objective: Non-ST elevation myocardial infarction NSTEMI is the most common type of acute coronary syndrome and has a poor prognosis. The SII and NS are derived from blood cell counts and reflects the balance between inherited and acquired immunity and the association between the immune system and endothelial dysfunction. This study aimed to compare the prognostic value of two novel inflammatory biomarkers, the systemic immune-inflammatory index SII and the Naples score NS, with that of other inflammatory markers and risk scores in patients with NSTEMI. Methods: This was a retrospective cohort analysis of 50 NSTEMI patients and 50 controls matched by age and sex who were admitted to our hospital. We calculated the SII and NS scores and other ratios, indices, and risk scores for each patient. We used Pearsons correlation coefficient and receiver operating characteristic ROC analysis to examine the correlations and predictive values of the SII index, NS score, and other biometric markers and risk scores. Results: The SII and NS were significantly greater in the NSTEMI group than in the control group. They had strong positive correlations with the NLR, MHR, PLR, and TCHDL ratio, and moderate positive correlations with TIMI and HEART scores r0.3, p0.01 for both. The SII and NS also had higher AUC values than other biometric markers and risk scores p0.05 for both. Conclusions: The SII and NS are inexpensive, widely available and easy to measure markers that may have utility for cardiac risk stratification in NSTEMI patients.

 Objective: Non-ST elevation myocardial infarction NSTEMI is the most common type of acute coronary syndrome and has a poor prognosis. The SII and NS are derived from blood cell counts and reflects the balance between inherited and acquired immunity and the association between the immune system and endothelial dysfunction. This study aimed to compare the prognostic value of two novel inflammatory biomarkers, the systemic immune-inflammatory index SII and the Naples score NS, with that of other inflammatory markers and risk scores in patients with NSTEMI. Methods: This was a retrospective cohort analysis of 50 NSTEMI patients and 50 controls matched by age and sex who were admitted to our hospital. We calculated the SII and NS scores and other ratios, indices, and risk scores for each patient. We used Pearsons correlation coefficient and receiver operating characteristic ROC analysis to examine the correlations and predictive values of the SII index, NS score, and other biometric markers and risk scores. Results: The SII and NS were significantly greater in the NSTEMI group than in the control group. They had strong positive correlations with the NLR, MHR, PLR, and TCHDL ratio, and moderate positive correlations with TIMI and HEART scores r0.3, p0.01 for both. The SII and NS also had higher AUC values than other biometric markers and risk scores p0.05 for both. Conclusions: The SII and NS are inexpensive, widely available and easy to measure markers that may have utility for cardiac risk stratification in NSTEMI patients.

Makale detayları

Evaluation of the Systemic Immune-Inflammatory Index (SII) and NAPLES Score (NS) in Patients with Non-ST-Elevation Myocardial Infarction (NSTEMI)

Yazarlar:

Mesut Gitmez

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.199-206

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319480

pISSN:

1300-2945

Non ST-elevation myocardial infarction

NAPLES Score

Systemic immune-inflammatory index

Novel inflammatory biomarkers

Sayı

Makale detayları

Evaluation of the Systemic Immune-Inflammatory Index (SII) and NAPLES Score (NS) in Patients with Non-ST-Elevation Myocardial Infarction (NSTEMI)

Yazarlar: Mesut Gitmez

Yayıncı: Dicle University

Ana Başlıklar: Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi: Dicle Tıp Dergisi Vol.51 Issue 2, pp.199-206

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001319480

pISSN: 1300-2945

Non ST-elevation myocardial infarction

NAPLES Score

Systemic immune-inflammatory index

Novel inflammatory biomarkers

Sayı

Yazarlar:

Mesut Gitmez

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.199-206

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319480

pISSN:

1300-2945