Potential evaluation of PVA-based hydrogels for biomedical applications

Emel TAMAHKAR; Bengi ÖZKAHRAMAN

doi:https://doi.org/10.17350/HJSE19030000021

Makale detayları

Potential evaluation of PVA-based hydrogels for biomedical applications

Yazarlar:

Emel TAMAHKAR | Bengi ÖZKAHRAMAN

Yayıncı:

Hitit University

Dergi:

Hittite Journal of Science and Engineering 2015 Vol.2 Issue 2, pp.165-171

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

İngilizce

Document ID (Org No.):

2000451903

Sıklık:

Üç Aylık

eISSN:

2148-4171

DOI:

https://doi.org/10.17350/HJSE19030000021

Özet:

 

P oly vinyl alcohol  PVA -based hydrogels prepared using freeze/thawing treatment have become increasingly important biomaterials for biomedical applications having great properties such as biocompatibility, biodegradability and high water absorbency. In this study, PVA-based physically cross-linked hydrogels were prepared with and without the presence of poly ethylene glycol  PEG  freezing at -16 °C for 16 h and thawing at room temperature for 8 h. The focus of this work was to address the effect of the addition of PEG  Mw: 2000 or 5000  and the effect of the number of freezing/thawing cycles on swelling behaviour. The Scanning Electron Microscopy  SEM  measurements demonstrated the morphological characteristics of PVA-based hydrogels indicating the formation of the macroporosity fabricated during freeze/thawing process. From the swelling tests undertaken it w as apparent that all the hydrogels exhibited unique swelling characteristics having high swelling degree at all pH values such as pH 2.1, 5.5 and 7.4 representing the pH values of stomach, blood and dermis. Thus, the hydrogels synthesized in this study present important potential for biomedical applications.

Makale detayları

Potential evaluation of PVA-based hydrogels for biomedical applications

Yazarlar: Emel TAMAHKAR | Bengi ÖZKAHRAMAN

Yayıncı: Hitit University

Dergi: Hittite Journal of Science and Engineering 2015 Vol.2 Issue 2, pp.165-171

Belge Tipi: Makale

Yayın Tarihi: 12/2015

Belge Dili: İngilizce

Document ID (Org No.): 2000451903

Sıklık: Üç Aylık

eISSN: 2148-4171

DOI: https://doi.org/10.17350/HJSE19030000021

Sayı

Yazarlar:

Emel TAMAHKAR | Bengi ÖZKAHRAMAN

Yayıncı:

Hitit University

Dergi:

Hittite Journal of Science and Engineering 2015 Vol.2 Issue 2, pp.165-171

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

İngilizce

Document ID (Org No.):

2000451903

Sıklık:

Üç Aylık

eISSN:

2148-4171

DOI:

https://doi.org/10.17350/HJSE19030000021