Effect of Low Fat and Low Cholesterol Diet Intervention on LDL Subgroups in Dyslipidemic Patients: Epidemiological Observational Study

Ülger Kaçar Mutlutürk; Betül Çiçek; Fahri Bayram; Fatma Doğruel

Makale detayları

Effect of Low Fat and Low Cholesterol Diet Intervention on LDL Subgroups in Dyslipidemic Patients: Epidemiological Observational Study

Yazarlar:

Ülger Kaçar Mutlutürk | Betül Çiçek | Fahri Bayram | Fatma Doğruel

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türkiye Diyabet ve Obezite Dergisi Vol.7 Issue 2, pp.145-151

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001297817

pISSN:

2587-0335

Anahtar kelimeler:

Özet:

 Aim: According to studies, the individual cardiovascular disease CVD risk is predicted and low density lipoprotein cholesterol LDL cholesterol sub-group concentration better than LDL cholesterol. High fat and cholesterol intakes are generally considered to pose a risk on CVD. The purpose of this study is to analogize LDL sub-group concentration pre and post a diet with LowFat and LowCholesterol written a prescription to dyslipidemic sicks along 3 months. Material and Methods: Diagnosticated dyslipidemia sicks n47 on the part of the endocrinologist were pursued along 3 months via a LowFat, LowCholesterol diet upon a lasting a month basis, on condition that they were proper for each. Before and after dietary intervention periods, biochemical parameters and anthropometric measurements were compared. Results: A sum of 47 participants 15 men and 32 women with an average age of 48.519.86 years were involved. 13 women were at premenopausal and 19 women were at postmenopausal stages of 32 women involved. Small dense LDL Sd-LDL decreased from 11.0 0.0-37.0 mgdL at the beginning to 7.0 0.0-68.1 mgdL after the dietary intervention, but this decline was unimportant p0.686. Midbands MiDC, MidB, MidA subgroups of intermediate density lipoprotein cholesterol IDL-cholesterol declined considerably after dietary interference p0.001, p0.008, p0.045, respectively. Conclusion: A LowFat and LowCholesterol diet prescribed to dyslipidemic sicks without using medicimes influencing lipid profile along 3 months, had a positive impact on decreasing the sub-groups of IDL-cholesterol and LDL-cholesterol. Also, this dietary intervention induced beneficial impacts on anthropometric indications, tension and blood lipid profiles of the patients. Trial Registration: ClinicalTrials.gov ID: NCT04894318. Release Date: May 15, 2021.

 Aim: According to studies, the individual cardiovascular disease CVD risk is predicted and low density lipoprotein cholesterol LDL cholesterol sub-group concentration better than LDL cholesterol. High fat and cholesterol intakes are generally considered to pose a risk on CVD. The purpose of this study is to analogize LDL sub-group concentration pre and post a diet with LowFat and LowCholesterol written a prescription to dyslipidemic sicks along 3 months. Material and Methods: Diagnosticated dyslipidemia sicks n47 on the part of the endocrinologist were pursued along 3 months via a LowFat, LowCholesterol diet upon a lasting a month basis, on condition that they were proper for each. Before and after dietary intervention periods, biochemical parameters and anthropometric measurements were compared. Results: A sum of 47 participants 15 men and 32 women with an average age of 48.519.86 years were involved. 13 women were at premenopausal and 19 women were at postmenopausal stages of 32 women involved. Small dense LDL Sd-LDL decreased from 11.0 0.0-37.0 mgdL at the beginning to 7.0 0.0-68.1 mgdL after the dietary intervention, but this decline was unimportant p0.686. Midbands MiDC, MidB, MidA subgroups of intermediate density lipoprotein cholesterol IDL-cholesterol declined considerably after dietary interference p0.001, p0.008, p0.045, respectively. Conclusion: A LowFat and LowCholesterol diet prescribed to dyslipidemic sicks without using medicimes influencing lipid profile along 3 months, had a positive impact on decreasing the sub-groups of IDL-cholesterol and LDL-cholesterol. Also, this dietary intervention induced beneficial impacts on anthropometric indications, tension and blood lipid profiles of the patients. Trial Registration: ClinicalTrials.gov ID: NCT04894318. Release Date: May 15, 2021.

 Aim: According to studies, the individual cardiovascular disease CVD risk is predicted and low density lipoprotein cholesterol LDL cholesterol sub-group concentration better than LDL cholesterol. High fat and cholesterol intakes are generally considered to pose a risk on CVD. The purpose of this study is to analogize LDL sub-group concentration pre and post a diet with LowFat and LowCholesterol written a prescription to dyslipidemic sicks along 3 months. Material and Methods: Diagnosticated dyslipidemia sicks n47 on the part of the endocrinologist were pursued along 3 months via a LowFat, LowCholesterol diet upon a lasting a month basis, on condition that they were proper for each. Before and after dietary intervention periods, biochemical parameters and anthropometric measurements were compared. Results: A sum of 47 participants 15 men and 32 women with an average age of 48.519.86 years were involved. 13 women were at premenopausal and 19 women were at postmenopausal stages of 32 women involved. Small dense LDL Sd-LDL decreased from 11.0 0.0-37.0 mgdL at the beginning to 7.0 0.0-68.1 mgdL after the dietary intervention, but this decline was unimportant p0.686. Midbands MiDC, MidB, MidA subgroups of intermediate density lipoprotein cholesterol IDL-cholesterol declined considerably after dietary interference p0.001, p0.008, p0.045, respectively. Conclusion: A LowFat and LowCholesterol diet prescribed to dyslipidemic sicks without using medicimes influencing lipid profile along 3 months, had a positive impact on decreasing the sub-groups of IDL-cholesterol and LDL-cholesterol. Also, this dietary intervention induced beneficial impacts on anthropometric indications, tension and blood lipid profiles of the patients. Trial Registration: ClinicalTrials.gov ID: NCT04894318. Release Date: May 15, 2021.

 Amaç: Çalışmalara göre, düşük yoğunluklu lipoprotein kolesterol LDL kolesterol alt grup konsantrasyonları bireysel kardiyovasküler hastalık KVH riskini, LDL kolesterolden daha iyi tahmin etmektedir. Yağ ve kolesterolün fazla alımları genellikle kardiyovasküler hastalık KVH için bir risk olarak kabul edilir. Bu çalışmanın amacı, dislipidemik hastalara 3 ay süreyle az yağlı ve az kolesterollü bir diyetin öncesi ve sonrası LDL alt grup konsantrasyonunu karşılaştırmaktır. Gereç ve Yöntemler: Endokrinolog tarafından dislipidemi tanısı konulan hastalar n47 aylık olarak her birine özel olmak kaydıyla az yağlı, az kolesterollü diyetle 3 ay izlendi. Diyet müdahale dönemleri öncesi ve sonrası, biyokimyasal parametreler ve antropometrik ölçümler karşılaştırıldı. Bulgular: Yaş ortalaması 48,519,86 olan toplam 47 katılımcı 15 erkek ve 32 kadın çalışmaya dahil edildi. Dahil edilen 32 kadından 13ü menopoz öncesi, 19u menopoz sonrası dönemdeydi. Çalışmanın başında 11,0 0,0-37,0 mgdL olan Small dense LDL Sd-LDL, diyet müdahalesinden sonra 7,0 0,0-68,1 mgdLye düştü, ancak anlamlı değildi p0,686. Orta yoğunluklu lipoprotein kolesterolün IDL-kolesterol alt grupları MiDA, MidB, MidC diyet sonrası önemli ölçüde azaldı sırasıyla, p0,045, p0,008, p0,001. Sonuç: Dislipidemik hastalara lipit profilini etkileyen ilaç kullanmayan 3 ay boyunca verilen az yağlı ve az kolesterollü diyet, LDLkolesterol ve IDL-kolesterol alt gruplarını düşürmede olumlu etki göstermiştir. Ayrıca bu diyet, hastaların antropometrik ölçümleri, kan basıncı ve kan lipid profilleri üzerinde yararlı etkilere neden olmuştur.

Makale detayları

Effect of Low Fat and Low Cholesterol Diet Intervention on LDL Subgroups in Dyslipidemic Patients: Epidemiological Observational Study

Yazarlar:

Ülger Kaçar Mutlutürk | Betül Çiçek | Fahri Bayram | Fatma Doğruel

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türkiye Diyabet ve Obezite Dergisi Vol.7 Issue 2, pp.145-151

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001297817

pISSN:

2587-0335

Dyslipidemia

LDL Sub-groups

IDL Sub-groups

LowFat LowCholesterol DietDislipidemi

LDL Alt Grupları

IDL Alt Grupları

Düşük Yağlı Düşük Kolesterollü Diyet

Sayı

Makale detayları

Yazarlar: Ülger Kaçar Mutlutürk | Betül Çiçek | Fahri Bayram | Fatma Doğruel

Yayıncı: Zonguldak Bulent Ecevit University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Türkiye Diyabet ve Obezite Dergisi Vol.7 Issue 2, pp.145-151

Belge Tipi: Makale

Yayın Tarihi: 8/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001297817

pISSN: 2587-0335

Sayı

Yazarlar:

Ülger Kaçar Mutlutürk | Betül Çiçek | Fahri Bayram | Fatma Doğruel

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türkiye Diyabet ve Obezite Dergisi Vol.7 Issue 2, pp.145-151

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001297817

pISSN:

2587-0335