Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma

Murat ÜNAL

Makale detayları

Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma

Yazarlar:

Murat ÜNAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2002 Vol.32 Issue 2, pp.139-143

Belge Tipi:

Makale

Yayın Tarihi:

1/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000757038

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

The aim of this study was to investigate the prognostic value of the thymidine labeling index (TLI) in laryngeal squamous cell carcinoma (SCC). The TLI in tumor tissue and adjacent healthy tissue was assessed prospectively in 31 patients and these values were correlated with age, TNM, grade and recurrence statistically. The tissues (tumoral and adjacent tumor-free tissue) that were obtained during surgery were labeled with 3H-Thymidine. TLI was calculated as the number of labeled tumor cells * 100 / total number of tumor cells. A statistically significant difference was observed between tumor tissue (mean TLI value = 17.62± 6.39%) and adjacent tumor-free tissue (mean TLI value = 9.16±3.32%) (p.

 

The aim of this study was to investigate the prognostic value of the thymidine labeling index (TLI) in laryngeal squamous cell carcinoma (SCC). The TLI in tumor tissue and adjacent healthy tissue was assessed prospectively in 31 patients and these values were correlated with age, TNM, grade and recurrence statistically. The tissues (tumoral and adjacent tumor-free tissue) that were obtained during surgery were labeled with 3H-Thymidine. TLI was calculated as the number of labeled tumor cells * 100 / total number of tumor cells. A statistically significant difference was observed between tumor tissue (mean TLI value = 17.62± 6.39%) and adjacent tumor-free tissue (mean TLI value = 9.16±3.32%) (p.

Makale detayları

Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma

Yazarlar:

Murat ÜNAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2002 Vol.32 Issue 2, pp.139-143

Belge Tipi:

Makale

Yayın Tarihi:

1/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000757038

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Thymidine labeling index

laryngeal squamous cell carcinoma

prognostic factors

Sayı

Makale detayları

Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma

Yazarlar: Murat ÜNAL

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2002 Vol.32 Issue 2, pp.139-143

Belge Tipi: Makale

Yayın Tarihi: 1/2002

Belge Dili: Türkçe

Document ID (Org No.): 2000757038

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Thymidine labeling index

laryngeal squamous cell carcinoma

prognostic factors

Sayı

Yazarlar:

Murat ÜNAL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2002 Vol.32 Issue 2, pp.139-143

Belge Tipi:

Makale

Yayın Tarihi:

1/2002

Belge Dili:

Türkçe

Document ID (Org No.):

2000757038

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144