Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis

Shruthi HEGDE; Vidya AJİLA; Subhas BABU; Suchetha KUMARİ; Harshini ULLAL; Ananya MADİYAL

Makale detayları

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis

Yazarlar:

Shruthi HEGDE | Vidya AJİLA | Subhas BABU | Suchetha KUMARİ | Harshini ULLAL | Ananya MADİYAL

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

European Oral Research 2018 Vol.52 Issue 3, pp.157-161

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000426267

eISSN:

2651-2823

pISSN:

2630-6158

Özet:

 



DOI: 10.26650/eor.2018.543


Purpose

Present study was undertaken to evaluate
and compare the salivary levels of tumour necrosis factor alpha (TNF-α) in subjects with RAS, traumatic ulcers (TUs) in the oral mucosa
and in healthy controls.

Materials and Methods

Present study involved 90 participants of
which 30 subjects were diagnosed with RAS, 30 subjects with TUs and 30 healthy
controls grouped as group 1, group 2 and group 3 respectively. Unstimulated
saliva was collected from the subjects through ‘Spit Technique’ and the estimation of TNF-α was done by
enzyme linked immunosorbent assay.  The
data collected was statistically analysed.

Results

Salivary level of TNF-α was
significantly higher in RAS patients than in patients with TUs and healthy
controls. Difference between the Salivary TNF-α
level in our study groups were statistically significant (p<0.001).

Conclusion

Present study suggests that saliva is a
convenient and ideal medium for the detection of TNF-α.  Statistically significant difference in the
level of salivary TNF-α between the RAS and TUs subjects as
well as controls suggests the significant contribution of TNF-α in pathogenesis of RAS.

.

Makale detayları

Evaluation of salivary tumour necrosis factor–alpha in patients with recurrent aphthous stomatitis

Yazarlar: Shruthi HEGDE | Vidya AJİLA | Subhas BABU | Suchetha KUMARİ | Harshini ULLAL | Ananya MADİYAL

Yayıncı: Istanbul University

Ana Başlıklar: Sağlık teşvikleri

Dergi: European Oral Research 2018 Vol.52 Issue 3, pp.157-161

Belge Tipi: Makale

Yayın Tarihi: 8/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000426267

eISSN: 2651-2823

pISSN: 2630-6158

Sayı

Yazarlar:

Shruthi HEGDE | Vidya AJİLA | Subhas BABU | Suchetha KUMARİ | Harshini ULLAL | Ananya MADİYAL

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

European Oral Research 2018 Vol.52 Issue 3, pp.157-161

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000426267

eISSN:

2651-2823

pISSN:

2630-6158