Is primary dysmenorrhea affected by gray matter volumetric changes in the brain?

Ela Kaplan; Selçuk Kaplan

Makale detayları

Is primary dysmenorrhea affected by gray matter volumetric changes in the brain?

Yazarlar:

Ela Kaplan | Selçuk Kaplan

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology | Radiology and Organ Imaging

Dergi:

The European Research Journal Vol.9 Issue 3, pp.495-501

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284942

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: We aimed this study to investigate the relationship between gray matter volume differences women who suffer from primary dismenorrea PD and asymptomatic women. Methods: Brain magnetic resonance MRI imaging of 113 PD patients and 113 healthy women were performed. The volume of gray matter structures was calculated with the VolBrain automatic calculation system. Results: Cut-off values were found by ROC analysis for right, left and total volumes in both groups. A caudate lobe volume above 6.33 cm3 is 99.1 sensitive and 77.9 specific for a diagnosis of PD. In addition, the volumes of other pain-related gray matter regions were decreased in PD patients  p  0.001. Conclusions: Atrophic changes in the medial GM structures in the brain in women with PD may cause hyperalgesia and the quantitative determination of these morphological changes may play an important role in the diagnosis of PD.

 Objectives: We aimed this study to investigate the relationship between gray matter volume differences women who suffer from primary dismenorrea PD and asymptomatic women. Methods: Brain magnetic resonance MRI imaging of 113 PD patients and 113 healthy women were performed. The volume of gray matter structures was calculated with the VolBrain automatic calculation system. Results: Cut-off values were found by ROC analysis for right, left and total volumes in both groups. A caudate lobe volume above 6.33 cm3 is 99.1 sensitive and 77.9 specific for a diagnosis of PD. In addition, the volumes of other pain-related gray matter regions were decreased in PD patients  p  0.001. Conclusions: Atrophic changes in the medial GM structures in the brain in women with PD may cause hyperalgesia and the quantitative determination of these morphological changes may play an important role in the diagnosis of PD.

 Objectives: We aimed this study to investigate the relationship between gray matter volume differences women who suffer from primary dismenorrea PD and asymptomatic women. Methods: Brain magnetic resonance MRI imaging of 113 PD patients and 113 healthy women were performed. The volume of gray matter structures was calculated with the VolBrain automatic calculation system. Results: Cut-off values were found by ROC analysis for right, left and total volumes in both groups. A caudate lobe volume above 6.33 cm3 is 99.1 sensitive and 77.9 specific for a diagnosis of PD. In addition, the volumes of other pain-related gray matter regions were decreased in PD patients  p  0.001. Conclusions: Atrophic changes in the medial GM structures in the brain in women with PD may cause hyperalgesia and the quantitative determination of these morphological changes may play an important role in the diagnosis of PD.

 Objectives: We aimed this study to investigate the relationship between gray matter volume differences women who suffer from primary dismenorrea PD and asymptomatic women. Methods: Brain magnetic resonance MRI imaging of 113 PD patients and 113 healthy women were performed. The volume of gray matter structures was calculated with the VolBrain automatic calculation system. Results: Cut-off values were found by ROC analysis for right, left and total volumes in both groups. A caudate lobe volume above 6.33 cm3 is 99.1 sensitive and 77.9 specific for a diagnosis of PD. In addition, the volumes of other pain-related gray matter regions were decreased in PD patients  p  0.001. Conclusions: Atrophic changes in the medial GM structures in the brain in women with PD may cause hyperalgesia and the quantitative determination of these morphological changes may play an important role in the diagnosis of PD.

Makale detayları

Is primary dysmenorrhea affected by gray matter volumetric changes in the brain?

Yazarlar:

Ela Kaplan | Selçuk Kaplan

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology | Radiology and Organ Imaging

Dergi:

The European Research Journal Vol.9 Issue 3, pp.495-501

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284942

pISSN:

2149-3189

Primary dysmenorrhea

gray matter volumetry

magnetic resonance imaging

thalamus

hippocampus

caudate nucleus

Sayı

Makale detayları

Is primary dysmenorrhea affected by gray matter volumetric changes in the brain?

Yazarlar: Ela Kaplan | Selçuk Kaplan

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Obstetrics and Gynaecology | Radiology and Organ Imaging

Dergi: The European Research Journal Vol.9 Issue 3, pp.495-501

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001284942

pISSN: 2149-3189

Primary dysmenorrhea

gray matter volumetry

magnetic resonance imaging

thalamus

hippocampus

caudate nucleus

Sayı

Yazarlar:

Ela Kaplan | Selçuk Kaplan

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Obstetrics and Gynaecology | Radiology and Organ Imaging

Dergi:

The European Research Journal Vol.9 Issue 3, pp.495-501

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284942

pISSN:

2149-3189