Factors affecting smear conversion in tuberculosis management

Aylin Babalık, Şule Kızıltaş, Hülya Arda

Makale detayları

Factors affecting smear conversion in tuberculosis management

Yazarlar:

Aylin Babalık, Şule Kızıltaş, Hülya Arda

Yayıncı:

Inonu University

Dergi:

Medicine Science 2012 Vol.1 Issue 4, pp.351-362

Belge Tipi:

Makale

Yayın Tarihi:

11/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000828813

Sıklık:

Üç Aylık

eISSN:

2147-0634

pISSN:

2147-0634

Anahtar kelimeler:

-

Özet:

 

ABSTRACT Setting: Inpatient clinic at Ministry of Health Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital Objective: To identify risk factors associated with persistent sputum positivity at the end of 2 months of direct observed treatment Design: Retrospective cohort study concerning evaluation of medical records of 547 patients with smear positive tuberculosis treated at our clinic from January 2004 to December 2005 Results: Of 547 patients with AFB positive smears, late conversion occurred in 11.9% while early conversion in 88.1%. Males composed 54.7% of the population, 31.9% of the population was â¤25 years old, 37.5% had exposure to tobacco, 15.7% had any drug resistance, 8.9% had co-morbid diabetes mellitus and 16.0% had extensive radiologic involvement. Based on significant association between sputum smear conversion and smoking for more than 20 package/year ( 20 package/year (OR=4.11; 95% CI=2.13-7.94) and extended radiological findings (OR=2.3; 95% CI=1.21-4.37) to be statistically significant predictors of sputum smear conversion. Conclusion: Our findings confirm the relationship between TB and tobacco and indicate smoking>20 package/year and extended radiological findings as significant independent predictors of sputum smear conversion.

 

ABSTRACT Setting: Inpatient clinic at Ministry of Health Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital Objective: To identify risk factors associated with persistent sputum positivity at the end of 2 months of direct observed treatment Design: Retrospective cohort study concerning evaluation of medical records of 547 patients with smear positive tuberculosis treated at our clinic from January 2004 to December 2005 Results: Of 547 patients with AFB positive smears, late conversion occurred in 11.9% while early conversion in 88.1%. Males composed 54.7% of the population, 31.9% of the population was â¤25 years old, 37.5% had exposure to tobacco, 15.7% had any drug resistance, 8.9% had co-morbid diabetes mellitus and 16.0% had extensive radiologic involvement. Based on significant association between sputum smear conversion and smoking for more than 20 package/year ( 20 package/year (OR=4.11; 95% CI=2.13-7.94) and extended radiological findings (OR=2.3; 95% CI=1.21-4.37) to be statistically significant predictors of sputum smear conversion. Conclusion: Our findings confirm the relationship between TB and tobacco and indicate smoking>20 package/year and extended radiological findings as significant independent predictors of sputum smear conversion.

Makale detayları

Factors affecting smear conversion in tuberculosis management

Yazarlar: Aylin Babalık, Şule Kızıltaş, Hülya Arda

Yayıncı: Inonu University

Dergi: Medicine Science 2012 Vol.1 Issue 4, pp.351-362

Belge Tipi: Makale

Yayın Tarihi: 11/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000828813

Sıklık: Üç Aylık

eISSN: 2147-0634

pISSN: 2147-0634

-

Sayı

Yazarlar:

Aylin Babalık, Şule Kızıltaş, Hülya Arda

Yayıncı:

Inonu University

Dergi:

Medicine Science 2012 Vol.1 Issue 4, pp.351-362

Belge Tipi:

Makale

Yayın Tarihi:

11/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000828813

Sıklık:

Üç Aylık

eISSN:

2147-0634

pISSN:

2147-0634