Apophysomyces elegans Caused Rhino-Orbito Mucormycosis: An Emerging Infection in Immunocompetent Individuals

N. Dhaneshwor Singh; Nishi Sharma; Lobzang Dawa; Shalini Malhotra

doi:https://doi.org/10.5799/jmid.369276

Makale detayları

Apophysomyces elegans Caused Rhino-Orbito Mucormycosis: An Emerging Infection in Immunocompetent Individuals

Yazarlar:

N. Dhaneshwor Singh | Nishi Sharma | Lobzang Dawa | Shalini Malhotra

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2017 Vol.07 Issue 04, pp.207-212

Belge Tipi:

Makale

Yayın Tarihi:

11/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000487453

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.369276

Özet:

 


Mucormycosis is a rare
necrotizing angioinvasive infection caused by fungi of the class Zygomycetes
(order Mucorales). It predominantly occurs in immunocompromised/ predisposed
individuals. Recent surge in its incidence in healthy individuals has emphasized
the need to reconsider our age-old presumption of 'mucormycosis as a classical
opportunistic infection'. Apophysomyces elegans has emerged as a pathogen
causing invasive Rhino-Orbitocerebral Mucormycosis (ROCM), mostly in
immunocompetent individuals. Mostly resistant to commonly used azoles and
echinocandins, management of A elegans
associated ROCM solely depends on radical debridement and Amphotericin B.
Recent reports of Amphotericin B resistant A
elegans strains is disturbing. Till date only 12 cases of ROCM in
immunocompetent/ otherwise healthy individuals attributable to A elegans has been reported.


Our main objective is to
delineate the clinical characteristics and treatment outcome of
immunocompentent/ otherwise healthy individuals suffering from A elegans caused ROCM. We also report
four new cases of A. elagans caused ROCM.
J Microbiol Infect Dis 2017; 7(4):207-212


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Makale detayları

Apophysomyces elegans Caused Rhino-Orbito Mucormycosis: An Emerging Infection in Immunocompetent Individuals

Yazarlar: N. Dhaneshwor Singh | Nishi Sharma | Lobzang Dawa | Shalini Malhotra

Yayıncı: Sağlık Araştırmaları Derneği

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Microbiology and Infectious Diseases 2017 Vol.07 Issue 04, pp.207-212

Belge Tipi: Makale

Yayın Tarihi: 11/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000487453

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/jmid.369276

Sayı

Yazarlar:

N. Dhaneshwor Singh | Nishi Sharma | Lobzang Dawa | Shalini Malhotra

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2017 Vol.07 Issue 04, pp.207-212

Belge Tipi:

Makale

Yayın Tarihi:

11/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000487453

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.369276