Preparation, Spectroscopic Studies and Biological Activity of Mono-organotin(IV) Derivatives of Non-Steroidal Anti-inflammatory Drugs

Azra JALAL; Saira SHAHZADI; Khadija SHAHID

Makale detayları

Preparation, Spectroscopic Studies and Biological Activity of Mono-organotin(IV) Derivatives of Non-Steroidal Anti-inflammatory Drugs

Yazarlar:

Azra JALAL | Saira SHAHZADI | Khadija SHAHID

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.629-644

Belge Tipi:

Makale

Yayın Tarihi:

4/2004

Belge Dili:

Türkçe

Document ID (Org No.):

2000729263

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

A set of 14 mono-organotin(IV) derivatives of general  formulae n-BuSnClL2 and n-BuSnL3, where `L' are various  non-steroidal anti-inflammatory drugs (NSAIDs), were synthesized and  structurally characterized by vibrational, 1H, 13C and 119Sn  spectroscopies and mass spectrometry to propose their structure.   Biological activity data (antibacterial, antifungal and cytotoxicity)  of the synthesized complexes were compared with the precursors to  establish the significance of the complexes.

 

A set of 14 mono-organotin(IV) derivatives of general  formulae n-BuSnClL2 and n-BuSnL3, where `L' are various  non-steroidal anti-inflammatory drugs (NSAIDs), were synthesized and  structurally characterized by vibrational, 1H, 13C and 119Sn  spectroscopies and mass spectrometry to propose their structure.   Biological activity data (antibacterial, antifungal and cytotoxicity)  of the synthesized complexes were compared with the precursors to  establish the significance of the complexes.

Makale detayları

Preparation, Spectroscopic Studies and Biological Activity of Mono-organotin(IV) Derivatives of Non-Steroidal Anti-inflammatory Drugs

Yazarlar: Azra JALAL | Saira SHAHZADI | Khadija SHAHID

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.629-644

Belge Tipi: Makale

Yayın Tarihi: 4/2004

Belge Dili: Türkçe

Document ID (Org No.): 2000729263

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Azra JALAL | Saira SHAHZADI | Khadija SHAHID

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2004 Vol.28 Issue 5, pp.629-644

Belge Tipi:

Makale

Yayın Tarihi:

4/2004

Belge Dili:

Türkçe

Document ID (Org No.):

2000729263

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527