The Effect Of Polymer Concentration On Coaxial Electrospinning Of Pvp/Pcl Core-Sheath Nanofibers

Nursema Pala Avcı; Nebahat Aral Yılmaz; Fatma Banu Nergis

Makale detayları

The Effect Of Polymer Concentration On Coaxial Electrospinning Of Pvp/Pcl Core-Sheath Nanofibers

Yazarlar:

Nursema Pala Avcı | Nebahat Aral Yılmaz | Fatma Banu Nergis

Yayıncı:

Gazi University

Ana Başlıklar:

Mühendislik

Dergi:

Politeknik Dergisi Vol.27 Issue 5, pp.1781-1787

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001331577

pISSN:

2147-9429

Anahtar kelimeler:

Özet:

 Core-sheath nanofibers are being developed with coaxial electrospinning for use in drug release studies. In this study, nanofiber structures were developed as hydrophobic PCL in the sheath and hydrophilic PVP in the core. The effect of polymer concentrations on fiber structure and water contact angle was observed by forming two different test groups. In the first group, fiber diameters were observed to decrease depending on viscosity as the polymer concentration decreased from 10 PCL  10 PVP to 6 PCL  6 PVP. It was also observed that the contact angle decreased from 104.3 to 57.61 as the concentration decreased. In the second group, the shell polymer ratio was kept constant as 10 wt PCL, while the core polymer ratio was decreased to 10 , 8 and 6. It was observed that the core polymer in the structure became hydrophilic as its viscosity decreased. Compared to the first group, the decrease in the contact angles of the surfaces was less since the shell polymer ratio was kept constant. Contact angles decreased from 104.3 to 96.29.

 Core-sheath nanofibers are being developed with coaxial electrospinning for use in drug release studies. In this study, nanofiber structures were developed as hydrophobic PCL in the sheath and hydrophilic PVP in the core. The effect of polymer concentrations on fiber structure and water contact angle was observed by forming two different test groups. In the first group, fiber diameters were observed to decrease depending on viscosity as the polymer concentration decreased from 10 PCL  10 PVP to 6 PCL  6 PVP. It was also observed that the contact angle decreased from 104.3 to 57.61 as the concentration decreased. In the second group, the shell polymer ratio was kept constant as 10 wt PCL, while the core polymer ratio was decreased to 10 , 8 and 6. It was observed that the core polymer in the structure became hydrophilic as its viscosity decreased. Compared to the first group, the decrease in the contact angles of the surfaces was less since the shell polymer ratio was kept constant. Contact angles decreased from 104.3 to 96.29.

 Core-sheath nanofibers are being developed with coaxial electrospinning for use in drug release studies. In this study, nanofiber structures were developed as hydrophobic PCL in the sheath and hydrophilic PVP in the core. The effect of polymer concentrations on fiber structure and water contact angle was observed by forming two different test groups. In the first group, fiber diameters were observed to decrease depending on viscosity as the polymer concentration decreased from 10 PCL  10 PVP to 6 PCL  6 PVP. It was also observed that the contact angle decreased from 104.3 to 57.61 as the concentration decreased. In the second group, the shell polymer ratio was kept constant as 10 wt PCL, while the core polymer ratio was decreased to 10 , 8 and 6. It was observed that the core polymer in the structure became hydrophilic as its viscosity decreased. Compared to the first group, the decrease in the contact angles of the surfaces was less since the shell polymer ratio was kept constant. Contact angles decreased from 104.3 to 96.29.

 Çekirdek-kabuk nanolifleri, ilaç salım çalışmalarında kullanılmak üzere koaksiyel elektroeğirme yöntemi ile geliştirilmektedir. Bu çalışmada, kabukta hidrofobik PCL ve çekirdekte hidrofilik PVP polimeri kullanılarak nanolifli yüzeyler geliştirilmiştir. Polimer konsantrasyonlarının lif yapısı ve su temas açısı üzerindeki etkisi iki farklı test grubu oluşturularak gözlemlendi. Birinci grupta polimer konsantrasyonu 10 PCL  10 PVPden 6 PCL  6 PVPye düştüğü için lif çaplarının viskoziteye bağlı olarak azaldığı gözlendi. Ayrıca konsantrasyon azaldıkça temas açısının 104,3den 57,61ye düştüğü gözlendi. İkinci grupta kabuk polimer oranı ağırlıkça 10 PCL olarak sabit tutulurken çekirdek polimer oranı ağırlıkça 10, 8 ve 6 şeklinde azaltılarak nanolifli yüzey üretimleri yapıldı. Yapıdaki çekirdek polimerin viskozitesi azaldıkça yüzeylerin hidrofilik hale geldiği ve temas açılarının 104,3den 96,29ye düştüğü gözlendi. Birinci grup ile kıyaslandığında kabuk polimer oranı sabit tutulduğu için yüzeylerin temas açılarındaki azalma daha az olmuştur.

Makale detayları

The Effect Of Polymer Concentration On Coaxial Electrospinning Of Pvp/Pcl Core-Sheath Nanofibers

Yazarlar:

Nursema Pala Avcı | Nebahat Aral Yılmaz | Fatma Banu Nergis

Yayıncı:

Gazi University

Ana Başlıklar:

Mühendislik

Dergi:

Politeknik Dergisi Vol.27 Issue 5, pp.1781-1787

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001331577

pISSN:

2147-9429

Nanofiber

Coaxial Electrospinning

Polycaprolactone

PolyvinylpyrrolidoneNanolif

Eşeksenli Elektroeğirme

Polikaprolakton

Polivinilpirolidon

Sayı

Makale detayları

Yazarlar: Nursema Pala Avcı | Nebahat Aral Yılmaz | Fatma Banu Nergis

Yayıncı: Gazi University

Ana Başlıklar: Mühendislik

Dergi: Politeknik Dergisi Vol.27 Issue 5, pp.1781-1787

Belge Tipi: Makale

Yayın Tarihi: 2/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001331577

pISSN: 2147-9429

Sayı

Yazarlar:

Nursema Pala Avcı | Nebahat Aral Yılmaz | Fatma Banu Nergis

Yayıncı:

Gazi University

Ana Başlıklar:

Mühendislik

Dergi:

Politeknik Dergisi Vol.27 Issue 5, pp.1781-1787

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001331577

pISSN:

2147-9429