Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

Elif Büyükkurt; Ömer Yılmaz; Bulent Albayrak; Ezel Bilge Yerli

Makale detayları

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

Yazarlar:

Elif Büyükkurt | Ömer Yılmaz | Bulent Albayrak | Ezel Bilge Yerli

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Gastroenterology and Hepatology

Dergi:

The European Research Journal Vol.10 Issue 1, pp.45-50

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001304904

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: The incidence of tuberculous peritonitis has been reported between 0.1 and 0.7 among all tuberculosis types. This study, it was aimed to evaluate the cases with tuberculous peritonitis, which has an important place in the differential diagnosis of patients with ascites, clinically, biochemically, microbiologically, and histopathologically. Methods: : Forty-nine patients with a definite clinical, radiological, and histopathological diagnosis of tuberculous peritonitis, which formed the basis of our study, were analyzed retrospectively. Results: The mean age of patients with tuberculous peritonitis was found to be 39.45  19.02 years. Purified-protein derivative PPD was positive in 23 72 of 32 patients with tuberculous peritonitis whose PPD results were recorded, in 9 28 PPD results were evaluated as anergic or negative. QuantiFERON-TB Gold In-Tube QFT-GIT test was sent in 10 of the patients, the result was positive in 9 90 patients and negative in 1 10 patient. There were 32 patients in whom tuberculosis polymerase chain reaction PCR was studied from ascitic fluid, 7 22 of the patients were PCR positive and 25 78 negative. Mycobacterium tuberculosis culture positivity was found in 18 69 of 26 patients who were biopsied. In total, 29 59 of the patients had M. tuberculosis culture positivity. Conclusions: Tuberculous peritonitis constitutes a public health problem in endemic regions of the world and tuberculous peritonitis should be considered in patients presenting with ascites. Despite all diagnostic difficulties, necessary tests, especially peritoneal biopsy, should be performed for early diagnosis, and it should not be forgotten that early initiation of treatment is very important in terms of morbidity and mortality of the disease.

 Objectives: The incidence of tuberculous peritonitis has been reported between 0.1 and 0.7 among all tuberculosis types. This study, it was aimed to evaluate the cases with tuberculous peritonitis, which has an important place in the differential diagnosis of patients with ascites, clinically, biochemically, microbiologically, and histopathologically. Methods: : Forty-nine patients with a definite clinical, radiological, and histopathological diagnosis of tuberculous peritonitis, which formed the basis of our study, were analyzed retrospectively. Results: The mean age of patients with tuberculous peritonitis was found to be 39.45  19.02 years. Purified-protein derivative PPD was positive in 23 72 of 32 patients with tuberculous peritonitis whose PPD results were recorded, in 9 28 PPD results were evaluated as anergic or negative. QuantiFERON-TB Gold In-Tube QFT-GIT test was sent in 10 of the patients, the result was positive in 9 90 patients and negative in 1 10 patient. There were 32 patients in whom tuberculosis polymerase chain reaction PCR was studied from ascitic fluid, 7 22 of the patients were PCR positive and 25 78 negative. Mycobacterium tuberculosis culture positivity was found in 18 69 of 26 patients who were biopsied. In total, 29 59 of the patients had M. tuberculosis culture positivity. Conclusions: Tuberculous peritonitis constitutes a public health problem in endemic regions of the world and tuberculous peritonitis should be considered in patients presenting with ascites. Despite all diagnostic difficulties, necessary tests, especially peritoneal biopsy, should be performed for early diagnosis, and it should not be forgotten that early initiation of treatment is very important in terms of morbidity and mortality of the disease.

 Objectives: The incidence of tuberculous peritonitis has been reported between 0.1 and 0.7 among all tuberculosis types. This study, it was aimed to evaluate the cases with tuberculous peritonitis, which has an important place in the differential diagnosis of patients with ascites, clinically, biochemically, microbiologically, and histopathologically. Methods: : Forty-nine patients with a definite clinical, radiological, and histopathological diagnosis of tuberculous peritonitis, which formed the basis of our study, were analyzed retrospectively. Results: The mean age of patients with tuberculous peritonitis was found to be 39.45  19.02 years. Purified-protein derivative PPD was positive in 23 72 of 32 patients with tuberculous peritonitis whose PPD results were recorded, in 9 28 PPD results were evaluated as anergic or negative. QuantiFERON-TB Gold In-Tube QFT-GIT test was sent in 10 of the patients, the result was positive in 9 90 patients and negative in 1 10 patient. There were 32 patients in whom tuberculosis polymerase chain reaction PCR was studied from ascitic fluid, 7 22 of the patients were PCR positive and 25 78 negative. Mycobacterium tuberculosis culture positivity was found in 18 69 of 26 patients who were biopsied. In total, 29 59 of the patients had M. tuberculosis culture positivity. Conclusions: Tuberculous peritonitis constitutes a public health problem in endemic regions of the world and tuberculous peritonitis should be considered in patients presenting with ascites. Despite all diagnostic difficulties, necessary tests, especially peritoneal biopsy, should be performed for early diagnosis, and it should not be forgotten that early initiation of treatment is very important in terms of morbidity and mortality of the disease.

 Objectives: The incidence of tuberculous peritonitis has been reported between 0.1 and 0.7 among all tuberculosis types. This study, it was aimed to evaluate the cases with tuberculous peritonitis, which has an important place in the differential diagnosis of patients with ascites, clinically, biochemically, microbiologically, and histopathologically. Methods: : Forty-nine patients with a definite clinical, radiological, and histopathological diagnosis of tuberculous peritonitis, which formed the basis of our study, were analyzed retrospectively. Results: The mean age of patients with tuberculous peritonitis was found to be 39.45  19.02 years. Purified-protein derivative PPD was positive in 23 72 of 32 patients with tuberculous peritonitis whose PPD results were recorded, in 9 28 PPD results were evaluated as anergic or negative. QuantiFERON-TB Gold In-Tube QFT-GIT test was sent in 10 of the patients, the result was positive in 9 90 patients and negative in 1 10 patient. There were 32 patients in whom tuberculosis polymerase chain reaction PCR was studied from ascitic fluid, 7 22 of the patients were PCR positive and 25 78 negative. Mycobacterium tuberculosis culture positivity was found in 18 69 of 26 patients who were biopsied. In total, 29 59 of the patients had M. tuberculosis culture positivity. Conclusions: Tuberculous peritonitis constitutes a public health problem in endemic regions of the world and tuberculous peritonitis should be considered in patients presenting with ascites. Despite all diagnostic difficulties, necessary tests, especially peritoneal biopsy, should be performed for early diagnosis, and it should not be forgotten that early initiation of treatment is very important in terms of morbidity and mortality of the disease.

Makale detayları

Tuberculous peritonitis: an analysis of case series of 49 consecutive patients

Yazarlar: Elif Büyükkurt | Ömer Yılmaz | Bulent Albayrak | Ezel Bilge Yerli

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Gastroenterology and Hepatology

Dergi: The European Research Journal Vol.10 Issue 1, pp.45-50

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001304904

pISSN: 2149-3189

Tuberculous peritonitis

diagnostic difficulties

ascites

Sayı

Yazarlar:

Elif Büyükkurt | Ömer Yılmaz | Bulent Albayrak | Ezel Bilge Yerli

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Gastroenterology and Hepatology

Dergi:

The European Research Journal Vol.10 Issue 1, pp.45-50

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001304904

pISSN:

2149-3189