THE EVALUATİON OF THE RELATİONSHİP BETWEEN 25OH-D VİTAMİN D LEVEL AND SLEEP QUALİTY AND METABOLİC PARAMETERS IN OBESE PATİENTS

Ayşenur Akın Poçanoğlu; Duygu İlke Yıldırım; Mehmet Ali Eryılmaz

Makale detayları

THE EVALUATİON OF THE RELATİONSHİP BETWEEN 25OH-D VİTAMİN D LEVEL AND SLEEP QUALİTY AND METABOLİC PARAMETERS IN OBESE PATİENTS

Yazarlar:

Ayşenur Akın Poçanoğlu | Duygu İlke Yıldırım | Mehmet Ali Eryılmaz

Yayıncı:

Istanbul Aydin University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Tıp Fakültesi Klinikleri Dergisi Vol.8 Issue 1, pp.15-30

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001342667

pISSN:

2630-5585

Anahtar kelimeler:

Özet:

 Objective: Vitamin D deficiency and poor quality sleep are common in obese patients. Although these three states are associated with each other, the relationship between these three variables has not been fully resolved. The aim of this study is to show the effect of 25-OH vitamin D deficiency, which is frequently encountered in patients diagnosed with obesity, on sleep quality and to evaluate the relationship of this vitamin with metabolic blood parameters. Material and Methods: This study is complement and cross sectional that it was addressed data of 317 patients who 18 years of age and older, who had a BMI 30 kg  m², without any additional disease and without medical treatment, who applied to the the department of Family Medicine in SBU Konya Training and Research Hospital in between 04.01.2019 and 10.31.2019. Socio-demographic data form and Pittsburgh Sleep Quality Index scale had been filled out to all patients who participating to the study. Blood parameters; 25-OH vitamin D, fasting insulin, HbA1c and lipid panel were evaluated together. Results: 82.6 n  262 of the patients were female and 17.4 n  55 were male, who included to the study.The mean age of the patients was 44.53  11.90 years. When patients were divided into groups according to their vitamin D levels, it were detected that 208 patients 65.7 are below 20 ng  mL of vitamin D level and 29 patients 9.1 are above 30 ng  mL. When patients was evaluated according to their PSQI Pittsburgh Sleep Quality Index levels, it was determined that 35.6 of patients scored 4 and below, 64.4 of patients scored 5 and above. It was determined that there was a negative correlation -r  0,119 p  0,035 between vitamin D values and PUQI values of the patients. Educational status, HDL, exercise status, and previously received psychiatric treatment is important determinant that affects the increase to PUKI levels in our univariate analysis. Exercise status odds ratio OR: 0.537; 95 Cl: 0.316-0.912; p  0.022 and receiving psychiatric treatment OR: 3.333; 95 Cl: 1.344-8.264; p  0.009 also has been identified as multivariable predictors affecting on the increase in PSQI levels. Conclusion: These results support that Vitamin D deficiency adversely affects sleep quality in obese patients. In addition low educational status of obese patients, high HDL valu, low level of exercise, and receiving psychiatric treatment of patients are decisives that effective on the deterioration of sleep quality. Supplementing vitamin D, which is quite simple and cheap to treat, increasing the level of exercise in obese and to correct their current mood will also positively affect sleep quality.

 Objective: Vitamin D deficiency and poor quality sleep are common in obese patients. Although these three states are associated with each other, the relationship between these three variables has not been fully resolved. The aim of this study is to show the effect of 25-OH vitamin D deficiency, which is frequently encountered in patients diagnosed with obesity, on sleep quality and to evaluate the relationship of this vitamin with metabolic blood parameters. Material and Methods: This study is complement and cross sectional that it was addressed data of 317 patients who 18 years of age and older, who had a BMI 30 kg  m², without any additional disease and without medical treatment, who applied to the the department of Family Medicine in SBU Konya Training and Research Hospital in between 04.01.2019 and 10.31.2019. Socio-demographic data form and Pittsburgh Sleep Quality Index scale had been filled out to all patients who participating to the study. Blood parameters; 25-OH vitamin D, fasting insulin, HbA1c and lipid panel were evaluated together. Results: 82.6 n  262 of the patients were female and 17.4 n  55 were male, who included to the study.The mean age of the patients was 44.53  11.90 years. When patients were divided into groups according to their vitamin D levels, it were detected that 208 patients 65.7 are below 20 ng  mL of vitamin D level and 29 patients 9.1 are above 30 ng  mL. When patients was evaluated according to their PSQI Pittsburgh Sleep Quality Index levels, it was determined that 35.6 of patients scored 4 and below, 64.4 of patients scored 5 and above. It was determined that there was a negative correlation -r  0,119 p  0,035 between vitamin D values and PUQI values of the patients. Educational status, HDL, exercise status, and previously received psychiatric treatment is important determinant that affects the increase to PUKI levels in our univariate analysis. Exercise status odds ratio OR: 0.537; 95 Cl: 0.316-0.912; p  0.022 and receiving psychiatric treatment OR: 3.333; 95 Cl: 1.344-8.264; p  0.009 also has been identified as multivariable predictors affecting on the increase in PSQI levels. Conclusion: These results support that Vitamin D deficiency adversely affects sleep quality in obese patients. In addition low educational status of obese patients, high HDL valu, low level of exercise, and receiving psychiatric treatment of patients are decisives that effective on the deterioration of sleep quality. Supplementing vitamin D, which is quite simple and cheap to treat, increasing the level of exercise in obese and to correct their current mood will also positively affect sleep quality.

 Objective: Vitamin D deficiency and poor quality sleep are common in obese patients. Although these three states are associated with each other, the relationship between these three variables has not been fully resolved. The aim of this study is to show the effect of 25-OH vitamin D deficiency, which is frequently encountered in patients diagnosed with obesity, on sleep quality and to evaluate the relationship of this vitamin with metabolic blood parameters. Material and Methods: This study is complement and cross sectional that it was addressed data of 317 patients who 18 years of age and older, who had a BMI 30 kg  m², without any additional disease and without medical treatment, who applied to the the department of Family Medicine in SBU Konya Training and Research Hospital in between 04.01.2019 and 10.31.2019. Socio-demographic data form and Pittsburgh Sleep Quality Index scale had been filled out to all patients who participating to the study. Blood parameters; 25-OH vitamin D, fasting insulin, HbA1c and lipid panel were evaluated together. Results: 82.6 n  262 of the patients were female and 17.4 n  55 were male, who included to the study.The mean age of the patients was 44.53  11.90 years. When patients were divided into groups according to their vitamin D levels, it were detected that 208 patients 65.7 are below 20 ng  mL of vitamin D level and 29 patients 9.1 are above 30 ng  mL. When patients was evaluated according to their PSQI Pittsburgh Sleep Quality Index levels, it was determined that 35.6 of patients scored 4 and below, 64.4 of patients scored 5 and above. It was determined that there was a negative correlation -r  0,119 p  0,035 between vitamin D values and PUQI values of the patients. Educational status, HDL, exercise status, and previously received psychiatric treatment is important determinant that affects the increase to PUKI levels in our univariate analysis. Exercise status odds ratio OR: 0.537; 95 Cl: 0.316-0.912; p  0.022 and receiving psychiatric treatment OR: 3.333; 95 Cl: 1.344-8.264; p  0.009 also has been identified as multivariable predictors affecting on the increase in PSQI levels. Conclusion: These results support that Vitamin D deficiency adversely affects sleep quality in obese patients. In addition low educational status of obese patients, high HDL valu, low level of exercise, and receiving psychiatric treatment of patients are decisives that effective on the deterioration of sleep quality. Supplementing vitamin D, which is quite simple and cheap to treat, increasing the level of exercise in obese and to correct their current mood will also positively affect sleep quality.

 Amaç: Obez hastalarda D vitamini eksikliği ve kalitesiz uyku sık görülen bir durumdur. Bu üç durum birbiri ile ilişkili olmasına rağmen bu üç değişken arasındaki ilişki tam çözülememiştir. Bu çalışmanın amacı obezite tanısı alan hastalarda çok sık karşılaşılan 25-OH D vitamini eksikliğinin; uyku kalitesi üzerine olan etkisini göstermek ve metabolik kan parametreleri ile olan ilişkisini değerlendirmektir. Gereç ve Yöntem: Çalışma 01.04.2019-31.10.2019 tarihleri arasında SBÜ Konya Eğitim ve Araştırma Hastanesi Aile hekimliği polikliniğine başvuran 18 yaş ve üzeri, VKİ 30 kgm² olan, herhangi bir ek hastalığı olmayan ve medikal tedavi almayan 317 hastanın verilerinin ele alındığı tanımlayıcı ve kesitsel bir çalışmadır. Çalışmaya dahil edilen tüm hastalara sosyodemografık veri formu ve Pittsburgh Uyku Kalite İndeksi ölçeği doldurtuldu. Hastaların kan parametreleri; 25-OH D vitamini, açlık insülini, HbA1c ve lipid paneli ile bu veri toplama formu ve uygulanan ölçek birlikte değerlendirildi. Bulgular: Çalışmaya alınan hastaların 82,6sı n262 kadın, 17,4ü n55 erkekti. Hastaların yaş ortalamaları 44.5311.90 yıl idi. Hastalar D vitamini duzeylerine gore gruplara ayrıldıgında; vitamin D seviyesi 20 ngmLnin altında 208 hasta 65,7, 30 ngmLnin uzerinde 29 hasta 9,1 saptandı. Hastalar PUKİ Pittsburgh Uyku Kalitesi İndeksi düzeylerine göre değerlendirildiğinde 35,6 hastanın 4 ve altında, 64,4 hastanın 5 ve üzerinde puan aldığı saptandı. Hastaların D vitamini değerleri ile PUKİ değerleri arasında negatif korelasyon olduğu -r0,119 p0,035 tespit edildi. Eğitim durumu, HDL, egzersiz durumu ve psikiyatrik tedavi alıpalmama durumu tek değişkenli analizlerimizde PUKİ düzeylerinin artışına etki eden önemli belirleyicilerdi. Egzersiz durumu odds ratio OR: 0.537; 95 Cl: 0.316-0.912; p0.022 ve psikiyatrik tedavi alıpalmama durumu OR:3.333; 95 Cl: 1.344-8.264; p0.009 ise PUKİ düzeylerinin artışına etki eden çok değişkenli prediktörler olarak tanımlandı. Sonuç: Bu sonuçlar; obez hastalarda D vitamini eksikliğinin uyku kalitesini olumsuz yönde etkilediğini desteklemektedir. Ayrıca obez hastaların eğitim durumunun kötü olması, HDL değerinin yüksekliği, egzersiz düzeyinin az olması ve hastaların psikiyatrik tedavi görmeleri uyku kalitesinin bozulmasına etki eden belirleyicilerdir. Tedavisi oldukça basit ve ucuz olan D vitamini takviyesini sağlamak, hastaların egzersiz durumunu artırmak ve mevcut ruhsal durumlarını düzeltmek uyku kalitesini de olumlu yönde etkileyecektir.

Makale detayları

THE EVALUATİON OF THE RELATİONSHİP BETWEEN 25OH-D VİTAMİN D LEVEL AND SLEEP QUALİTY AND METABOLİC PARAMETERS IN OBESE PATİENTS

Yazarlar:

Ayşenur Akın Poçanoğlu | Duygu İlke Yıldırım | Mehmet Ali Eryılmaz

Yayıncı:

Istanbul Aydin University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Tıp Fakültesi Klinikleri Dergisi Vol.8 Issue 1, pp.15-30

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001342667

pISSN:

2630-5585

Vitamin D

Obesity

Sleep qualityD vitamini,

Obezite

Uyku Kalitesi

Sayı

Makale detayları

THE EVALUATİON OF THE RELATİONSHİP BETWEEN 25OH-D VİTAMİN D LEVEL AND SLEEP QUALİTY AND METABOLİC PARAMETERS IN OBESE PATİENTS

Yazarlar: Ayşenur Akın Poçanoğlu | Duygu İlke Yıldırım | Mehmet Ali Eryılmaz

Yayıncı: Istanbul Aydin University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Tıp Fakültesi Klinikleri Dergisi Vol.8 Issue 1, pp.15-30

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: Türkçe

Document ID (Org No.): 2001342667

pISSN: 2630-5585

Vitamin D

Obesity

Sleep qualityD vitamini,

Obezite

Uyku Kalitesi

Sayı

Yazarlar:

Ayşenur Akın Poçanoğlu | Duygu İlke Yıldırım | Mehmet Ali Eryılmaz

Yayıncı:

Istanbul Aydin University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Tıp Fakültesi Klinikleri Dergisi Vol.8 Issue 1, pp.15-30

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001342667

pISSN:

2630-5585