Mesenchymal stem-cell derived treatment in osteosarcoma between 1993-2023: Bibliometric study

Akif Mirioğlu

Makale detayları

Mesenchymal stem-cell derived treatment in osteosarcoma between 1993-2023: Bibliometric study

Yazarlar:

Akif Mirioğlu

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.20 Issue 1, pp.71-77

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343478

pISSN:

1303-6610

Anahtar kelimeler:

Özet:

 Objective: Osteosarcoma is a malignant bone tumor with a high incidence in adolescence and childhood. Treatment is long and difficult, including chemotherapy, radiotherapy, and orthopedic surgery. Stem cell-derived treatment has also recently been studied in osteosarcoma. In this bibliometric study, we aimed to illuminate the trend of research between osteosarcoma and stem cell-derived treatment. Materials and Methods: Publications on osteosarcoma were retrieved from the Web of Science Core Collection. R studio software and the VOS viewer analysis program were used for data analysis. Results: There were 853 publications with an average of 7.7 publications per year. The most productive countries were the USA and China respectively. According to the categorical classification described in the WoS, oncology 41.7, and cell biology 18.1 were the first two fields in terms of diagnosis and treatment, while pathology 3.7 and orthopedics 2.2 had lower levels of work. However, the most cited author locally was Gibbs from the University of Florida University of Alberta UF Orthopedic  Sports Med Inst. in the USA. The keywords cancer stem cell, bone cancer, and mesenchymal stem cell had been determined to have strong links to osteosarcoma. Cancer Res was the most cited journal. Conclusion: As a result, it has been found that research presenting strong links to the relationship between cell-derived therapy and osteosarcoma has shown an increase in recent years.

 Objective: Osteosarcoma is a malignant bone tumor with a high incidence in adolescence and childhood. Treatment is long and difficult, including chemotherapy, radiotherapy, and orthopedic surgery. Stem cell-derived treatment has also recently been studied in osteosarcoma. In this bibliometric study, we aimed to illuminate the trend of research between osteosarcoma and stem cell-derived treatment. Materials and Methods: Publications on osteosarcoma were retrieved from the Web of Science Core Collection. R studio software and the VOS viewer analysis program were used for data analysis. Results: There were 853 publications with an average of 7.7 publications per year. The most productive countries were the USA and China respectively. According to the categorical classification described in the WoS, oncology 41.7, and cell biology 18.1 were the first two fields in terms of diagnosis and treatment, while pathology 3.7 and orthopedics 2.2 had lower levels of work. However, the most cited author locally was Gibbs from the University of Florida University of Alberta UF Orthopedic  Sports Med Inst. in the USA. The keywords cancer stem cell, bone cancer, and mesenchymal stem cell had been determined to have strong links to osteosarcoma. Cancer Res was the most cited journal. Conclusion: As a result, it has been found that research presenting strong links to the relationship between cell-derived therapy and osteosarcoma has shown an increase in recent years.

 Objective: Osteosarcoma is a malignant bone tumor with a high incidence in adolescence and childhood. Treatment is long and difficult, including chemotherapy, radiotherapy, and orthopedic surgery. Stem cell-derived treatment has also recently been studied in osteosarcoma. In this bibliometric study, we aimed to illuminate the trend of research between osteosarcoma and stem cell-derived treatment. Materials and Methods: Publications on osteosarcoma were retrieved from the Web of Science Core Collection. R studio software and the VOS viewer analysis program were used for data analysis. Results: There were 853 publications with an average of 7.7 publications per year. The most productive countries were the USA and China respectively. According to the categorical classification described in the WoS, oncology 41.7, and cell biology 18.1 were the first two fields in terms of diagnosis and treatment, while pathology 3.7 and orthopedics 2.2 had lower levels of work. However, the most cited author locally was Gibbs from the University of Florida University of Alberta UF Orthopedic  Sports Med Inst. in the USA. The keywords cancer stem cell, bone cancer, and mesenchymal stem cell had been determined to have strong links to osteosarcoma. Cancer Res was the most cited journal. Conclusion: As a result, it has been found that research presenting strong links to the relationship between cell-derived therapy and osteosarcoma has shown an increase in recent years.

 Amaç: Osteosarkom, ergenlik ve çocukluk çağında görülme sıklığı yüksek olan kötü huylu bir kemik tümörüdür. Osteosarkom tedavisi kemoterapi, radyoterapi ve ortopedik cerrahiyi içeren uzun ve zorlu bir süreçtir. Kök hücre kaynaklı tedavi de osteosarkomda son zamanlarda çalışılmaktadır. Bu bibliyometrik çalışmada, osteosarkom ve kök hücre kaynaklı tedavi arasındaki araştırma eğilimini aydınlatmayı amaçladık. Materiyal ve Metod: Osteosarkom ile ilgili yayınlar Web of Science Core Collectiondan alınmıştır. Veri analizi için R studio yazılımı ve VOS viewer analiz programı kullanılmıştır. Bulgular: Yapılan analizde 853 yayın olduğu ve her yılla ortalama 7,7 yayın düşmekteydi. En üretken ülkeler ilk sırayı ABD ve ikinci sırayı Çin olmıştır. WoSta tanımlanan kategorik sınıflandırmaya göre, onkoloji 41,7 ve hücre biyolojisi 18,1 tanı ve tedavi açısından ilk iki alan olurken, patoloji 3,7 ve ortopedi 2,2 daha düşük çalışma seviyelerine sahipti. Ancak, en çok atıf alan yazar Gibbs idi. USA; University of Florida University of Alberta UF Orthopedic  Sports Med Inst. cancer stem cell, bone cancer ve mesenchymal stem cell anahtar kelimelerinin osteosarkomla güçlü bağlantıları olduğu belirlenmiştir. Bunun yanında, Cancer Res. en çok atıf alan dergi olduğu belirlenmiştir. Sonuç: Sonuç olarak, hücre kaynaklı tedavi ile osteosarkom arasında güçlü bir ilişki ortaya koyan ilişki araştırmasıyla olan bağlantıların son yıllarda artış gösterdiği tespit edildi.

Makale detayları

Mesenchymal stem-cell derived treatment in osteosarcoma between 1993-2023: Bibliometric study

Yazarlar:

Akif Mirioğlu

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.20 Issue 1, pp.71-77

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343478

pISSN:

1303-6610

Stem cells

Osteosarcoma

BibliometricsOsteosarcoma

kök hücre

bibliyometri

Sayı

Makale detayları

Mesenchymal stem-cell derived treatment in osteosarcoma between 1993-2023: Bibliometric study

Yazarlar: Akif Mirioğlu

Yayıncı: Kahramanmaras Sutcu Imam University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.20 Issue 1, pp.71-77

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001343478

pISSN: 1303-6610

Stem cells

Osteosarcoma

BibliometricsOsteosarcoma

kök hücre

bibliyometri

Sayı

Yazarlar:

Akif Mirioğlu

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.20 Issue 1, pp.71-77

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343478

pISSN:

1303-6610