Peripheral Adropin Application Regulates Nutritional Behavior and Fat Tissue-mediated Energy Metabolism

Ersen ERASLAN; Tuncer NACAR; Ayhan TANYELİ; Mustafa Can GÜLER; Elif POLAT; Ali Sefa MENDİL; Elif POLAT; Mustafa ÖZKARACA

Makale detayları

Peripheral Adropin Application Regulates Nutritional Behavior and Fat Tissue-mediated Energy Metabolism

Yazarlar:

Ersen ERASLAN | Tuncer NACAR | Ayhan TANYELİ | Mustafa Can GÜLER | Elif POLAT | Ali Sefa MENDİL | Elif POLAT | Mustafa ÖZKARACA

Yayıncı:

Ağrı İbrahim Çeçen University

Dergi:

Eastern Anatolian Journal of Science 2020 Vol.6 Issue 1, pp.35-45

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000949739

Sıklık:

İki Yıllık

pISSN:

2149-6137

Özet:

 

Adropin is a peptide hormone that is involved in food and energy homeostasis and has many metabolic roles. Although previous studies attempted to explain the relation between Adropin and nutritional behavior, there is no strong evidence. In the present study, the effects of peripheral Adropin administration on various signals related to nutritional behavior was investigated in rats at doses of 4 μg/kg and 40 μg/kg by using biochemical and histopathological analyses. It was shown that Adropin reduces feed and water consumption in rats. It was also shown that these effects occur through various neuron groups in the central area by affecting many peripheral signals. Adropin modulates many signals contributing to nutritional behavior.

Makale detayları

Peripheral Adropin Application Regulates Nutritional Behavior and Fat Tissue-mediated Energy Metabolism

Yazarlar: Ersen ERASLAN | Tuncer NACAR | Ayhan TANYELİ | Mustafa Can GÜLER | Elif POLAT | Ali Sefa MENDİL | Elif POLAT | Mustafa ÖZKARACA

Yayıncı: Ağrı İbrahim Çeçen University

Dergi: Eastern Anatolian Journal of Science 2020 Vol.6 Issue 1, pp.35-45

Belge Tipi: Makale

Yayın Tarihi: 6/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000949739

Sıklık: İki Yıllık

pISSN: 2149-6137

Sayı

Yazarlar:

Ersen ERASLAN | Tuncer NACAR | Ayhan TANYELİ | Mustafa Can GÜLER | Elif POLAT | Ali Sefa MENDİL | Elif POLAT | Mustafa ÖZKARACA

Yayıncı:

Ağrı İbrahim Çeçen University

Dergi:

Eastern Anatolian Journal of Science 2020 Vol.6 Issue 1, pp.35-45

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000949739

Sıklık:

İki Yıllık

pISSN:

2149-6137