Anti-Parkinson's activity and in vitro antioxidant activity of Origanum majorana plant extract

N.A.

Makale detayları

Anti-Parkinson's activity and in vitro antioxidant activity of Origanum majorana plant extract

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.26 Issue 6, pp.1814-1824

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347792

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 Neurodegenerative diseases are increasing worldwide, and new drugs to treat them effectively with fewer side effects are in high demand today. Treatments available for these diseases are associated with significant side effects in the long term. Therefore, finding a therapy that inhibits disease progression with fewer side effects is crucial. Origanum majorana commonly called sweet marjoram was reported to have a wide range of health benefits particularly in treating neurological diseases. In this context, the leaf extract of Origanum majorana was evaluated for its antioxidant, antiparkinsons and neuroprotective properties. The antioxidant property was assessed by two in-vitro methods, nitric oxide radical scavenging assay and phosphomolybdenum assay. The antiparkinsons property was assessed in haloperidol-induced Parkinsons disease in mice using the catalepsy bar test and rotarod test. The results of this study show that Origanum Majorana has a powerful antioxidant property that can protect neurons from haloperidol-induced cognitive and motor impairments by reducing oxidation.

 Neurodegenerative diseases are increasing worldwide, and new drugs to treat them effectively with fewer side effects are in high demand today. Treatments available for these diseases are associated with significant side effects in the long term. Therefore, finding a therapy that inhibits disease progression with fewer side effects is crucial. Origanum majorana commonly called sweet marjoram was reported to have a wide range of health benefits particularly in treating neurological diseases. In this context, the leaf extract of Origanum majorana was evaluated for its antioxidant, antiparkinsons and neuroprotective properties. The antioxidant property was assessed by two in-vitro methods, nitric oxide radical scavenging assay and phosphomolybdenum assay. The antiparkinsons property was assessed in haloperidol-induced Parkinsons disease in mice using the catalepsy bar test and rotarod test. The results of this study show that Origanum Majorana has a powerful antioxidant property that can protect neurons from haloperidol-induced cognitive and motor impairments by reducing oxidation.

 Neurodegenerative diseases are increasing worldwide, and new drugs to treat them effectively with fewer side effects are in high demand today. Treatments available for these diseases are associated with significant side effects in the long term. Therefore, finding a therapy that inhibits disease progression with fewer side effects is crucial. Origanum majorana commonly called sweet marjoram was reported to have a wide range of health benefits particularly in treating neurological diseases. In this context, the leaf extract of Origanum majorana was evaluated for its antioxidant, antiparkinsons and neuroprotective properties. The antioxidant property was assessed by two in-vitro methods, nitric oxide radical scavenging assay and phosphomolybdenum assay. The antiparkinsons property was assessed in haloperidol-induced Parkinsons disease in mice using the catalepsy bar test and rotarod test. The results of this study show that Origanum Majorana has a powerful antioxidant property that can protect neurons from haloperidol-induced cognitive and motor impairments by reducing oxidation.

 Neurodegenerative diseases are increasing worldwide, and new drugs to treat them effectively with fewer side effects are in high demand today. Treatments available for these diseases are associated with significant side effects in the long term. Therefore, finding a therapy that inhibits disease progression with fewer side effects is crucial. Origanum majorana commonly called sweet marjoram was reported to have a wide range of health benefits particularly in treating neurological diseases. In this context, the leaf extract of Origanum majorana was evaluated for its antioxidant, antiparkinsons and neuroprotective properties. The antioxidant property was assessed by two in-vitro methods, nitric oxide radical scavenging assay and phosphomolybdenum assay. The antiparkinsons property was assessed in haloperidol-induced Parkinsons disease in mice using the catalepsy bar test and rotarod test. The results of this study show that Origanum Majorana has a powerful antioxidant property that can protect neurons from haloperidol-induced cognitive and motor impairments by reducing oxidation.

Makale detayları

Anti-Parkinson's activity and in vitro antioxidant activity of Origanum majorana plant extract

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.26 Issue 6, pp.1814-1824

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347792

pISSN:

2630-6344

Neurodegenerative diseases

Origanum majorana

Parkinson

antioxidant and neuroprotective properties

Sayı

Makale detayları

Anti-Parkinson's activity and in vitro antioxidant activity of Origanum majorana plant extract

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.26 Issue 6, pp.1814-1824

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001347792

pISSN: 2630-6344

Neurodegenerative diseases

Origanum majorana

Parkinson

antioxidant and neuroprotective properties

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.26 Issue 6, pp.1814-1824

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347792

pISSN:

2630-6344