Seropositivity of Cytomegalovirus, Rubella and Toxoplasma Gondii in Pregnant Women and IgG Avidity Tests

Cemal Çiçek; Altan Akıneden; Selçuk Türkel

Makale detayları

Seropositivity of Cytomegalovirus, Rubella and Toxoplasma Gondii in Pregnant Women and IgG Avidity Tests

Yazarlar:

Cemal Çiçek | Altan Akıneden | Selçuk Türkel

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 1, pp.26-31

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284394

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: Cytomegalovirus CMV, Rubella, and Toxoplasma gondii T.gondii infections cause congenital malformations in the fetus when they occur in pregnant women, especially in the first trimester. This study aimed to determine the seropositivity of CMV, Rubella, and T.gondii in pregnant women. Materials and Methods: CMV, Rubella, and T. gondii seropositivity rates of pregnant women who applied to the Aksaray Training and Research Hospital Microbiology Laboratory between July 2019 and June 2021 were evaluated. In addition, the avidity test results studied during this period were included in the study. Results: A total of 3218 pregnant women were included in the study. CMV, Rubella, and T.gondii IgM seropositivity rates were 1.9, 0.8, and 1.4, respectively, and these rates for IgG were 97.3, 83.9, and 21, respectively. All the samples were found to have high avidity in CMV and Rubella. In the T.gondii group, 93.7 of women had high, and 6.7 had low avidity. Conclusion: CMV, Rubella, and T.gondii seropositivity were determined for the first time in Aksaray province in this study. These rates we found are similar to other studies in our country. No difference was found in CMV IgM and IgG according to age groups, while a decrease was found in Rubella with age. In T.gondii, on the other hand, it was observed that there was an increase in IgG with age, while the rate did not change in IgM.

 Purpose: Cytomegalovirus CMV, Rubella, and Toxoplasma gondii T.gondii infections cause congenital malformations in the fetus when they occur in pregnant women, especially in the first trimester. This study aimed to determine the seropositivity of CMV, Rubella, and T.gondii in pregnant women. Materials and Methods: CMV, Rubella, and T. gondii seropositivity rates of pregnant women who applied to the Aksaray Training and Research Hospital Microbiology Laboratory between July 2019 and June 2021 were evaluated. In addition, the avidity test results studied during this period were included in the study. Results: A total of 3218 pregnant women were included in the study. CMV, Rubella, and T.gondii IgM seropositivity rates were 1.9, 0.8, and 1.4, respectively, and these rates for IgG were 97.3, 83.9, and 21, respectively. All the samples were found to have high avidity in CMV and Rubella. In the T.gondii group, 93.7 of women had high, and 6.7 had low avidity. Conclusion: CMV, Rubella, and T.gondii seropositivity were determined for the first time in Aksaray province in this study. These rates we found are similar to other studies in our country. No difference was found in CMV IgM and IgG according to age groups, while a decrease was found in Rubella with age. In T.gondii, on the other hand, it was observed that there was an increase in IgG with age, while the rate did not change in IgM.

 Purpose: Cytomegalovirus CMV, Rubella, and Toxoplasma gondii T.gondii infections cause congenital malformations in the fetus when they occur in pregnant women, especially in the first trimester. This study aimed to determine the seropositivity of CMV, Rubella, and T.gondii in pregnant women. Materials and Methods: CMV, Rubella, and T. gondii seropositivity rates of pregnant women who applied to the Aksaray Training and Research Hospital Microbiology Laboratory between July 2019 and June 2021 were evaluated. In addition, the avidity test results studied during this period were included in the study. Results: A total of 3218 pregnant women were included in the study. CMV, Rubella, and T.gondii IgM seropositivity rates were 1.9, 0.8, and 1.4, respectively, and these rates for IgG were 97.3, 83.9, and 21, respectively. All the samples were found to have high avidity in CMV and Rubella. In the T.gondii group, 93.7 of women had high, and 6.7 had low avidity. Conclusion: CMV, Rubella, and T.gondii seropositivity were determined for the first time in Aksaray province in this study. These rates we found are similar to other studies in our country. No difference was found in CMV IgM and IgG according to age groups, while a decrease was found in Rubella with age. In T.gondii, on the other hand, it was observed that there was an increase in IgG with age, while the rate did not change in IgM.

 Amaç: Sitomegalovirus CMV, Rubella ve Toksoplasma gondii T.gondii enfeksiyonları, gebe kadınlarda, özellikle ilk trimesterde ortaya çıktığında fetusta konjenital malformasyona neden olmaktadır. Bu çalışmada gebelerde CMV, Rubella ve T.gondii seropozitifliğinin belirlenmesi amaçlanmıştır. Araçlar ve Yöntem: Temmuz 2019-Haziran 2021 tarihleri arasında, Aksaray Eğitim ve Araştırma Hastanesi Mikrobiyoloji Laboratuvarına başvuran gebelere ait CMV, Rubella ve T.gondii seropozitiflik oranları retrospektif olarak incelendi. Ayrıca bu dönemde çalışılan avidite test sonuçlarına bakıldı. Bulgular: Çalışmaya toplam 3218 gebe alındı. CMV, Rubella ve T.gondii IgM seropozitiflik oranları sırasıyla 1.9, 0.8 ve 1.4 iken, Ig G de bu oranlar, sırasıyla 97.3, 83.9, 21 dir. CMVde ve Rubellada örneklerin tamamının yüksek avidite olduğu saptandı. T.gondii de ise 93.7si yüksek ve 6.7si düşük avidite olduğu görüldü. Sonuç: Aksaray ilinde ilk kez bu çalışma ile CMV, Rubella ve T.gondii seropozitiflikleri belirlenmiştir. Bulduğumuz bu oranlar ülkemizdeki diğer çalışmalarla benzerlik göstermektedir. Yaş gruplarına göre CMV IgM ve IgGde fark bulunamamış, Rubellada ise yaşla beraber azalma saptanmıştır. T.gondiide ise IgGde yaşla beraber artış olduğu görülürken, IgM de oranın değişmediği görülmüştür.

Makale detayları

Seropositivity of Cytomegalovirus, Rubella and Toxoplasma Gondii in Pregnant Women and IgG Avidity Tests

Yazarlar:

Cemal Çiçek | Altan Akıneden | Selçuk Türkel

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 1, pp.26-31

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284394

pISSN:

2619-9203

Cytomegalovirus

Rubella

Toxoplasma gondii

Avidity

pergnancy

Sitomegalovirus,

Rubella

Toksoplasma gondii

Avidite

gebelik

Sayı

Makale detayları

Yazarlar: Cemal Çiçek | Altan Akıneden | Selçuk Türkel

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Ahi Evran Tıp Dergisi Vol.7 Issue 1, pp.26-31

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001284394

pISSN: 2619-9203

Sayı

Yazarlar:

Cemal Çiçek | Altan Akıneden | Selçuk Türkel

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Ahi Evran Tıp Dergisi Vol.7 Issue 1, pp.26-31

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001284394

pISSN:

2619-9203