The Clinical Predictive Value of the Neutrophil to Lymphocyte Ratio as a Biomarker in Lumbar Disc Herniation

Ali YILMAZ; Hilal ALTAŞ; Timur YILDIRIM; Şükran KAYGISIZ; Hasan Serdar IŞIK

doi:https://doi.org/10.19127/mbsjohs.594555

Makale detayları

The Clinical Predictive Value of the Neutrophil to Lymphocyte Ratio as a Biomarker in Lumbar Disc Herniation

Yazarlar:

Ali YILMAZ | Hilal ALTAŞ | Timur YILDIRIM | Şükran KAYGISIZ | Hasan Serdar IŞIK

Yayıncı:

Ordu University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 2, pp.145-150

Belge Tipi:

Makale

Yayın Tarihi:

8/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000564324

Sıklık:

Üç Yıllık

eISSN:

2149-7796

DOI:

https://doi.org/10.19127/mbsjohs.594555

Özet:

 





Objective: Low back pain is a frequently seen problem in the society and causes loss
of labor. Although etiology of lumbar disc herniation is multi-factorial it is
known that it is determinant for the etiology of intervertebral disc
degeneration herniation. In recent studies, it has been shown that it has an
efficient role in the process of inflamation and inflamatory cytokine disc. We
aimed to investigate the association between the neutrophil to Lymphocyte Ratio  level as an inflammatory biomarker in
patients with lumbar disc herniation.




Methods: 394 patients between the age
of 18-80 applying to our center because of low back pain complaint and having
lumbar MR were included in the study. The patients were divided into two groups
as having lumbar disc hernia and not having based on the lumbar MR result.
Blood samples were taken from all patients during application and neutrophil lymphocyte
rates were calculated.  




Results.  Average age of group with lumbar disc hernia
was 46 and 55 of these cases were female and 45 of them were male. N/L rate was
measured as 3.81+/-1.85 (p=0.001) in the group having lumbar disc hernia and
significant difference compared to the control group was noted. It was found
out that lifting weight (β=0.121 95% Cl (0.052-0.281), P<0.001),BMI
(β=0.226, 95% Cl (0.080-0.640) P=0.005), DM (β=0.268 95% Cl (0.074-0.969),
P=0.045), smoking (β=3.226 95% Cl (1,343-7.749), P<0.009), educational
background (β=5.268 95% Cl (1.941-9.796), P=0.001) and NLR (β=1.302 95% Cl
(1.013-1.673), P=0.039) were the independent predictors in the presence of
lumbar disc herniation. 




Conclusion:
NLR may be used as a simple and reliable premise independent predictor of
lumbar disc herniation in patients with low back pain.





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Makale detayları

The Clinical Predictive Value of the Neutrophil to Lymphocyte Ratio as a Biomarker in Lumbar Disc Herniation

Yazarlar: Ali YILMAZ | Hilal ALTAŞ | Timur YILDIRIM | Şükran KAYGISIZ | Hasan Serdar IŞIK

Yayıncı: Ordu University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 2, pp.145-150

Belge Tipi: Makale

Yayın Tarihi: 8/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000564324

Sıklık: Üç Yıllık

eISSN: 2149-7796

DOI: https://doi.org/10.19127/mbsjohs.594555

Sayı

Yazarlar:

Ali YILMAZ | Hilal ALTAŞ | Timur YILDIRIM | Şükran KAYGISIZ | Hasan Serdar IŞIK

Yayıncı:

Ordu University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Middle Black Sea Journal of Health Science 2019 Vol.5 Issue 2, pp.145-150

Belge Tipi:

Makale

Yayın Tarihi:

8/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000564324

Sıklık:

Üç Yıllık

eISSN:

2149-7796

DOI:

https://doi.org/10.19127/mbsjohs.594555