A novel one-pot and rapid synthesis of polyfunctionalized benzo[a]pyrimido[5’,4’:5,6] pyrido[2,3-c]phenazine derivatives under microwave irradiation

Mahdieh TABIBIAN; Razieh MOHEBAT; Masoumeh TABATABAEE

Makale detayları

A novel one-pot and rapid synthesis of polyfunctionalized benzo[a]pyrimido[5’,4’:5,6] pyrido[2,3-c]phenazine derivatives under microwave irradiation

Yazarlar:

Mahdieh TABIBIAN | Razieh MOHEBAT | Masoumeh TABATABAEE

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2018 Vol.42 Issue 4, pp.1008-1017

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000726036

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 


 
                         A one-pot, environmentally friendly, and efficient protocol for the 
synthesis of novel polyfunctionalized 
benzo[a a  aaa]pyrimido[5',4':5,6]pyrido[2,3-c c  ccc]phenazine derivatives has been 
reported by a one-pot, four-component sequential reaction between 
2-hydroxynaphthalene-1,4-dione, benzene-1,2-diamines, benzaldehydes, and 
6-amino-1,3-dimethyluracil in the presence of p p  ppp-TSA as a nontoxic, 
inexpensive, ecofriendly, and efficacious solid acid catalyst. Two C-C 
bonds, two C=N bonds, and one C-N bond, as well as two new rings, were formed in 
this reaction. Through this procedure, compounds with substantial biological 
and pharmaceutical properties are generated in a single operation. Factors 
such as high yields, less reaction time, operational simplicity, and lack of 
any dangerous reagents/solvents have made this process a green one.
                    

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Makale detayları

A novel one-pot and rapid synthesis of polyfunctionalized benzo[a]pyrimido[5’,4’:5,6] pyrido[2,3-c]phenazine derivatives under microwave irradiation

Yazarlar: Mahdieh TABIBIAN | Razieh MOHEBAT | Masoumeh TABATABAEE

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2018 Vol.42 Issue 4, pp.1008-1017

Belge Tipi: Makale

Yayın Tarihi: 8/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000726036

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Mahdieh TABIBIAN | Razieh MOHEBAT | Masoumeh TABATABAEE

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2018 Vol.42 Issue 4, pp.1008-1017

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000726036

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527