Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)

KATARZYNA MICHALEK; EWA CZERNIAWSKA-PIATKOWSKA; MARTA GRABOWSKA; MARIA LASZCZYNSKA

Makale detayları

Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)

Yazarlar:

KATARZYNA MICHALEK | EWA CZERNIAWSKA-PIATKOWSKA | MARTA GRABOWSKA | MARIA LASZCZYNSKA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 5, pp.692-697

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811841

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

Abstract: Mammalian aquaporins (AQPs) are a family of at least 13 small, integral membrane proteins expressed in various fluid-transporting epithelial cells. Aquaporin 2 (AQP2) is mainly expressed in the kidneys, where it plays an important role in the reabsorption of water from the renal tubular fluid to concentrate urine. Studies of AQP2 expression in the kidneys have been performed in humans, monkeys, sheep, dogs, rabbits, rats, mice, and cattle. We analyzed the expression of AQP2 in the kidneys of wild boars (Sus scrofa). AQP2 was localized in the principal cells of collecting ducts in medullary rays penetrating the renal cortex and in the collecting duct of the renal medulla. The presence of AQP2 was confirmed mainly in the apical plasma membrane but also in the intracellular components and basolateral membrane of the principal cells of the collecting ducts. Due to the key role of AQP2 in the regulation of water balance in mammals and the lack of studies in the literature concerning analysis of this protein in wild boars, this work completes the present state of knowledge by providing new information on immunolocalization and immunoexpression of aquaporin 2 in Sus scrofa kidneys.

 

Abstract: Mammalian aquaporins (AQPs) are a family of at least 13 small, integral membrane proteins expressed in various fluid-transporting epithelial cells. Aquaporin 2 (AQP2) is mainly expressed in the kidneys, where it plays an important role in the reabsorption of water from the renal tubular fluid to concentrate urine. Studies of AQP2 expression in the kidneys have been performed in humans, monkeys, sheep, dogs, rabbits, rats, mice, and cattle. We analyzed the expression of AQP2 in the kidneys of wild boars (Sus scrofa). AQP2 was localized in the principal cells of collecting ducts in medullary rays penetrating the renal cortex and in the collecting duct of the renal medulla. The presence of AQP2 was confirmed mainly in the apical plasma membrane but also in the intracellular components and basolateral membrane of the principal cells of the collecting ducts. Due to the key role of AQP2 in the regulation of water balance in mammals and the lack of studies in the literature concerning analysis of this protein in wild boars, this work completes the present state of knowledge by providing new information on immunolocalization and immunoexpression of aquaporin 2 in Sus scrofa kidneys.

Makale detayları

Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)

Yazarlar:

KATARZYNA MICHALEK | EWA CZERNIAWSKA-PIATKOWSKA | MARTA GRABOWSKA | MARIA LASZCZYNSKA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 5, pp.692-697

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811841

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Aquaporin 2

wild boars

immunohistochemistry

kidney

Sayı

Makale detayları

Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)

Yazarlar: KATARZYNA MICHALEK | EWA CZERNIAWSKA-PIATKOWSKA | MARTA GRABOWSKA | MARIA LASZCZYNSKA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Biology 2015 Vol.39 Issue 5, pp.692-697

Belge Tipi: Makale

Yayın Tarihi: 12/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000811841

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Aquaporin 2

wild boars

immunohistochemistry

kidney

Sayı

Yazarlar:

KATARZYNA MICHALEK | EWA CZERNIAWSKA-PIATKOWSKA | MARTA GRABOWSKA | MARIA LASZCZYNSKA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 5, pp.692-697

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811841

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152