Comparison Of The Relationship Between Inflammatory Markers And Saphenous Vein Graft Disease In Patients With Stable Angina Pectoris.

Çağrı Zorlu; Sefa Erdi Ömür; Samet Yılmaz

Makale detayları

Comparison Of The Relationship Between Inflammatory Markers And Saphenous Vein Graft Disease In Patients With Stable Angina Pectoris.

Yazarlar:

Çağrı Zorlu | Sefa Erdi Ömür | Samet Yılmaz

Yayıncı:

Alanya Alaaddin Keykubat Üniversitesi

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Acta Medica Alanya Vol.7 Issue 3, pp.213-218

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001309269

pISSN:

2587-0319

Anahtar kelimeler:

Özet:

 Aim: Coronary artery bypass graft surgery is one of the most commonly used strategies to revascularization of occlusive coronary atherosclerotic lesions. Atherosclerosis is known to be a chronic inflammatory process. Many inflammatory cells and mechanisms are active in this process. Markers such as mean platelet volume-to-lymphocyte ratio MPVLR and C-reactive protein-to-albumin CAR which may be associated with the severity of inflammation. In this study, it was aimed to determine the relationship between these parameters and saphenous vein graft SVG diseases. Methods: In this retrospective study, 314 patients SVG disease with stable angina pectoris were included. Patients were divided into two groups according to the severity of SVG disease. We compared 159 patients who had severe stenosis in SVG and 156 patients who did not,in terms of CAR, NLR, PLR, MPVLR. Results: Patients who 50 stenosis in SVG had significantly higher CAR, MPVLR, NLR, and PLR respectively 9.1 4.2-16.8 p0.001, 4.50.68 p0.001, 2.4 0.69 p0.002, 153 6 p0.048. In line with these data, CAR and MPVLR values were also higher in the group with 50 stenosis in SVG, which was highly statistically significant respectively 3.2 0.9-4.4 vs 9.1 4.2-16.8; p0.001 and 3.640.43 vs 4.530.68; p0.001. Conclusion: C-reactive protein-to-albumin and MPVLR can be a useful and easily accessible markers to predict severity SVG stenosis.

 Aim: Coronary artery bypass graft surgery is one of the most commonly used strategies to revascularization of occlusive coronary atherosclerotic lesions. Atherosclerosis is known to be a chronic inflammatory process. Many inflammatory cells and mechanisms are active in this process. Markers such as mean platelet volume-to-lymphocyte ratio MPVLR and C-reactive protein-to-albumin CAR which may be associated with the severity of inflammation. In this study, it was aimed to determine the relationship between these parameters and saphenous vein graft SVG diseases. Methods: In this retrospective study, 314 patients SVG disease with stable angina pectoris were included. Patients were divided into two groups according to the severity of SVG disease. We compared 159 patients who had severe stenosis in SVG and 156 patients who did not,in terms of CAR, NLR, PLR, MPVLR. Results: Patients who 50 stenosis in SVG had significantly higher CAR, MPVLR, NLR, and PLR respectively 9.1 4.2-16.8 p0.001, 4.50.68 p0.001, 2.4 0.69 p0.002, 153 6 p0.048. In line with these data, CAR and MPVLR values were also higher in the group with 50 stenosis in SVG, which was highly statistically significant respectively 3.2 0.9-4.4 vs 9.1 4.2-16.8; p0.001 and 3.640.43 vs 4.530.68; p0.001. Conclusion: C-reactive protein-to-albumin and MPVLR can be a useful and easily accessible markers to predict severity SVG stenosis.

 Aim: Coronary artery bypass graft surgery is one of the most commonly used strategies to revascularization of occlusive coronary atherosclerotic lesions. Atherosclerosis is known to be a chronic inflammatory process. Many inflammatory cells and mechanisms are active in this process. Markers such as mean platelet volume-to-lymphocyte ratio MPVLR and C-reactive protein-to-albumin CAR which may be associated with the severity of inflammation. In this study, it was aimed to determine the relationship between these parameters and saphenous vein graft SVG diseases. Methods: In this retrospective study, 314 patients SVG disease with stable angina pectoris were included. Patients were divided into two groups according to the severity of SVG disease. We compared 159 patients who had severe stenosis in SVG and 156 patients who did not,in terms of CAR, NLR, PLR, MPVLR. Results: Patients who 50 stenosis in SVG had significantly higher CAR, MPVLR, NLR, and PLR respectively 9.1 4.2-16.8 p0.001, 4.50.68 p0.001, 2.4 0.69 p0.002, 153 6 p0.048. In line with these data, CAR and MPVLR values were also higher in the group with 50 stenosis in SVG, which was highly statistically significant respectively 3.2 0.9-4.4 vs 9.1 4.2-16.8; p0.001 and 3.640.43 vs 4.530.68; p0.001. Conclusion: C-reactive protein-to-albumin and MPVLR can be a useful and easily accessible markers to predict severity SVG stenosis.

 Amaç: Koroner arter baypas greft cerrahisi, tıkayıcı koroner aterosklerotik lezyonların revaskülarizasyonu için en sık kullanılan stratejilerden biridir. Aterosklerozun kronik bir inflamatuar süreç olduğu bilinmektedir. Bu süreçte birçok enflamatuar hücre ve mekanizma aktiftir. Enflamasyonun ciddiyeti ile ilişkili olabilecek biyobelirteçler; ortalama trombosit hacmi-lenfosit oranı MPVLR ve C-reaktif protein-albümin CAR, nötrofil-lenfosit oranı NLR ve platelet-lenfosit oranı PLRdir. Bu çalışmada bu parametreler ile safen ven grefti SVG hastalıkları arasındaki ilişkinin belirlenmesi amaçlanmıştır. Yöntemler: Bu retrospektif çalışmaya stabil anjina pektorisli SVG hastalığı olan 314 hasta dahil edildi. Hastalar SVG hastalığının şiddetine göre iki gruba ayrıldı. SVGde ciddi darlık olan 159 hasta ile darlık olmayan 156 hastayı CAR, NLR, PLR, MPVLR açısından karşılaştırdık. Bulgular: SVGde 50 darlığı olan hastalarda CAR, MPVLR, NLR ve PLR anlamlı olarak daha yüksekti sırasıyla 9.1 4.2-16.8 p0.001, 4.50.68 p0.001, 2.4 0.69 p0.002, 153 6 p0.048. Bu veriler doğrultusunda SVGde 50 darlık olan grupta CAR ve MPVLR değerleri de istatistiksel olarak anlamlıydı sırasıyla 3,2 0,9-4,4 ve 9,1 4,2-16,8; p0,001 ve 3,64 0,43 - 4,530,68; p0.001. Sonuç: C-reaktif protein-albümin ve MPVLR, SVG stenozunun ciddiyetini tahmin etmek için yararlı ve kolay erişilebilir bir belirteç olabilir.

Makale detayları

Comparison Of The Relationship Between Inflammatory Markers And Saphenous Vein Graft Disease In Patients With Stable Angina Pectoris.

Yazarlar:

Çağrı Zorlu | Sefa Erdi Ömür | Samet Yılmaz

Yayıncı:

Alanya Alaaddin Keykubat Üniversitesi

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Acta Medica Alanya Vol.7 Issue 3, pp.213-218

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001309269

pISSN:

2587-0319

C-reactive protein-to-albumin

mean platelet volume-to-lymphocytes ratio

neutrophil-to-lymphocyte ratio

platelet-to-lymphocyte ratio

saphenous vein graft diseases.C-reactive protein-albumin oranı

ortalama platelet hacmi- lenfosit oranı

nötrofil-lenfosit oranı

platelet-lenfosit oranı

safen ven greft hastalığı

Sayı

Makale detayları

Yazarlar: Çağrı Zorlu | Sefa Erdi Ömür | Samet Yılmaz

Yayıncı: Alanya Alaaddin Keykubat Üniversitesi

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Acta Medica Alanya Vol.7 Issue 3, pp.213-218

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001309269

pISSN: 2587-0319

Sayı

Yazarlar:

Çağrı Zorlu | Sefa Erdi Ömür | Samet Yılmaz

Yayıncı:

Alanya Alaaddin Keykubat Üniversitesi

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Acta Medica Alanya Vol.7 Issue 3, pp.213-218

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001309269

pISSN:

2587-0319