Antimicrobial Susceptibility of Brucella melitensis Isolates from Blood Samples

Ergin AYAŞLIOĞLU; Selçuk KILIÇ; Kemalettin AYDIN

Makale detayları

Antimicrobial Susceptibility of Brucella melitensis Isolates from Blood Samples

Yazarlar:

Ergin AYAŞLIOĞLU | Selçuk KILIÇ | Kemalettin AYDIN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 3, pp.257-262

Belge Tipi:

Makale

Yayın Tarihi:

2/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755818

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Aim: Brucellosis is a worldwide zoonotic disease that remains an important public health problem in rural Turkey. The aim of the present study was to identify Brucella species and biotypes, and to assess the antimicrobial susceptibility of isolates from blood samples.   Materials and Methods: The study included 46 Brucella isolates from the Kırıkkale region of central Anatolia. The identification and biotyping of the isolates were based on conventional methods. The minimal inhibitory concentration (MIC) values of tetracycline, rifampin, streptomycin, ciprofloxacin, and azithromycin were determined using the E test method.   Results: All isolates were identified as B. melitensis (45 isolates, biotype-3) and were sensitive to tetracycline, streptomycin, ciprofloxacin, and azithromycin. In all, 2 isolates showed intermediate sensitivity to rifampin, whereas the others were sensitive. MIC90 values of tetracycline, streptomycin, rifampin, ciprofloxacin, and azithromycin were 0.25 mg/l, 0.50 mg/l, 1.0 mg/l, 0.25 mg/l, and 1.0 mg/l, respectively.   Conclusions: In recent years there has been tremendous interest in the identification of Brucella strains and their antimicrobial susceptibility. According to antimicrobial susceptibility test results, none of the isolates in the Kırıkkale region of Turkey were resistant to the currently recommended antibiotics. The present study´s findings were discussed along with a brief review of similar studies from Turkey.

 

Aim: Brucellosis is a worldwide zoonotic disease that remains an important public health problem in rural Turkey. The aim of the present study was to identify Brucella species and biotypes, and to assess the antimicrobial susceptibility of isolates from blood samples.   Materials and Methods: The study included 46 Brucella isolates from the Kırıkkale region of central Anatolia. The identification and biotyping of the isolates were based on conventional methods. The minimal inhibitory concentration (MIC) values of tetracycline, rifampin, streptomycin, ciprofloxacin, and azithromycin were determined using the E test method.   Results: All isolates were identified as B. melitensis (45 isolates, biotype-3) and were sensitive to tetracycline, streptomycin, ciprofloxacin, and azithromycin. In all, 2 isolates showed intermediate sensitivity to rifampin, whereas the others were sensitive. MIC90 values of tetracycline, streptomycin, rifampin, ciprofloxacin, and azithromycin were 0.25 mg/l, 0.50 mg/l, 1.0 mg/l, 0.25 mg/l, and 1.0 mg/l, respectively.   Conclusions: In recent years there has been tremendous interest in the identification of Brucella strains and their antimicrobial susceptibility. According to antimicrobial susceptibility test results, none of the isolates in the Kırıkkale region of Turkey were resistant to the currently recommended antibiotics. The present study´s findings were discussed along with a brief review of similar studies from Turkey.

Makale detayları

Antimicrobial Susceptibility of Brucella melitensis Isolates from Blood Samples

Yazarlar: Ergin AYAŞLIOĞLU | Selçuk KILIÇ | Kemalettin AYDIN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2008 Vol.38 Issue 3, pp.257-262

Belge Tipi: Makale

Yayın Tarihi: 2/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000755818

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Brucellosis

tetracycline

streptomycin

rifampin

ciprofloxacin

azithromycin

Sayı

Yazarlar:

Ergin AYAŞLIOĞLU | Selçuk KILIÇ | Kemalettin AYDIN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2008 Vol.38 Issue 3, pp.257-262

Belge Tipi:

Makale

Yayın Tarihi:

2/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000755818

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144