Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes

Alper ÇOLAK; Murat TAŞ; Gazi İREZ; Orhan BÜYÜKGÜNGÖR; Ferdağ ÇOLAK; Handan GÜNAY

Makale detayları

Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes

Yazarlar:

Alper ÇOLAK | Murat TAŞ | Gazi İREZ | Orhan BÜYÜKGÜNGÖR | Ferdağ ÇOLAK | Handan GÜNAY

Yayıncı:

Gebze Teknik University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Acta Materialia Turcica 2017 Vol.1 Issue 1, pp.11-19

Belge Tipi:

Makale

Yayın Tarihi:

12/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000439907

Sıklık:

Yıllık

pISSN:

2630-5909

Özet:

 


The
2-methyl-2-(1-hydroxyiminoethyl)-1,2,3,4-tetrahydroquinazoline (HL or 1) and its novel Ni(II) complexes, square-planar
[Ni(L)(LH)]·(NO3) (2) and
octahedral [NiCl2(LH)(H2O)2]·(H2O) (3), have been synthesized. The ligand and complexes
have been characterized by means of elemental, IR, UV-Vis. spectroscopic
studies, 1H-NMR, 13C-NMR, magnetic susceptibility,
thermal analysis, mass spectroscopy and X-ray diffraction technique. The HL
ligand crystallizes in the P21/c. Antimicrobial activity of ligand (1) and complexes (2 and 3) was evaluated by
the agar diffusion method. Complex 2 showed weak antimicrobial activity against
tested microorganism strains. Complex 3 exhibited moderate antimicrobial activity
against Staphylococcus epidermidis
and Candida albicans.


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Makale detayları

Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes

Yazarlar: Alper ÇOLAK | Murat TAŞ | Gazi İREZ | Orhan BÜYÜKGÜNGÖR | Ferdağ ÇOLAK | Handan GÜNAY

Yayıncı: Gebze Teknik University

Ana Başlıklar: Kimya mühendisliği

Dergi: Acta Materialia Turcica 2017 Vol.1 Issue 1, pp.11-19

Belge Tipi: Makale

Yayın Tarihi: 12/2017

Belge Dili: İngilizce

Document ID (Org No.): 2000439907

Sıklık: Yıllık

pISSN: 2630-5909

Sayı

Yazarlar:

Alper ÇOLAK | Murat TAŞ | Gazi İREZ | Orhan BÜYÜKGÜNGÖR | Ferdağ ÇOLAK | Handan GÜNAY

Yayıncı:

Gebze Teknik University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Acta Materialia Turcica 2017 Vol.1 Issue 1, pp.11-19

Belge Tipi:

Makale

Yayın Tarihi:

12/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000439907

Sıklık:

Yıllık

pISSN:

2630-5909