Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?

Sibel YURT; Lale TUNA; Halit ÇINARKA; Mehmet TOPTAŞ; Kemal KARAPINAR; Gamze KIRKIL

doi:https://doi.org/10.16899/jcm.776695

Makale detayları

Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?

Yazarlar:

Sibel YURT | Lale TUNA | Halit ÇINARKA | Mehmet TOPTAŞ | Kemal KARAPINAR | Gamze KIRKIL

Yayıncı:

Rabia YILMAZ

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Contemporary Medicine 2020 Vol.10 Issue 4, pp.481-486

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000496889

Sıklık:

İki Aylık

eISSN:

2667-7180

DOI:

https://doi.org/10.16899/jcm.776695

Özet:

 

Introduction:This study was designed to assess whether there is a relation between inflammatory biomarkers such as NLR, PLR and psoas muscle area (PMA) as a marker of sarcopenia in COPD pateints who admitted to the emergency department of our clinic. Method: Retrospectivly one hundred forty three COPD patients who had CT scan for any reason during hospital admission were included. Patient characteristics and clinical and laboratory data were evaluated retrospectively. Results:In our study, we performed the correlations between NLR, PLR and CRP, FEV1, FVC, FEV1/FVC, right PMA, left PMA, total PMA. NLR and PLR were positively correlated with CRP (r=0.60, p<0.001, r=0.37, p<0.001, respectively), and no correlation was observed between NLR, PLR, CRP and all PMA values. However, there was a positive correlation between all PMA values and FEV1, FEV1/FVC parameters. There was no correlation between sarcopenia and emergency admission frequency and mortality. Conclusion NLR, and PLR may have a role as a biomarker of inflammation in COPD and its exacerbation. Sarcopenia is an expected finding in COPD patients, but relation between sarcopenia and inflammation requires further investigation.

Makale detayları

Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?

Yazarlar: Sibel YURT | Lale TUNA | Halit ÇINARKA | Mehmet TOPTAŞ | Kemal KARAPINAR | Gamze KIRKIL

Yayıncı: Rabia YILMAZ

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Contemporary Medicine 2020 Vol.10 Issue 4, pp.481-486

Belge Tipi: Makale

Yayın Tarihi: 12/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000496889

Sıklık: İki Aylık

eISSN: 2667-7180

DOI: https://doi.org/10.16899/jcm.776695

Sayı

Yazarlar:

Sibel YURT | Lale TUNA | Halit ÇINARKA | Mehmet TOPTAŞ | Kemal KARAPINAR | Gamze KIRKIL

Yayıncı:

Rabia YILMAZ

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Contemporary Medicine 2020 Vol.10 Issue 4, pp.481-486

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000496889

Sıklık:

İki Aylık

eISSN:

2667-7180

DOI:

https://doi.org/10.16899/jcm.776695