Synthesis, characterization and antimicrobial studies of new chiral amide-Schiff base derivatives

Seda YÜKSEKDANACI; Demet ASTLEY; İhsan YAŞA

doi:https://doi.org/10.15671/hjbc.520248

Makale detayları

Synthesis, characterization and antimicrobial studies of new chiral amide-Schiff base derivatives

Yazarlar:

Seda YÜKSEKDANACI | Demet ASTLEY | İhsan YAŞA

Yayıncı:

Hacettepe University

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Hacettepe Journal of Biology and Chemistry 2020 Vol.48 Issue 1, pp.33-39

Belge Tipi:

Makale

Yayın Tarihi:

4/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000448305

Sıklık:

Üç Aylık

eISSN:

2687-475X

pISSN:

2687-475X

DOI:

https://doi.org/10.15671/hjbc.520248

Özet:

 


In this study, new chiral Schiff bases (3-9) obtained from the reaction of chiral amide derivatives with different substituted aromatic aldehyde were synthesized. All synthesized compounds structures were characterized by FTIR, 1H-NMR, 13C-NMR and elemental analysis. All of the new synthesized compounds were tested in vitro against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Salmonella thyphimirium, Klebsiella pneumoniae, Enterococcus faecalis, Pseudomonas aeruginosa, Candida albicans for their antibacterial and antifungal activities. All compounds have shown moderate to good antibacterial activity against Gram-positive and Gram-negative bacteria.  Among the compounds tested compound 7 showed most potent inhibitory action against test organisms.


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Makale detayları

Synthesis, characterization and antimicrobial studies of new chiral amide-Schiff base derivatives

Yazarlar: Seda YÜKSEKDANACI | Demet ASTLEY | İhsan YAŞA

Yayıncı: Hacettepe University

Ana Başlıklar: Uygulamalı fizik

Dergi: Hacettepe Journal of Biology and Chemistry 2020 Vol.48 Issue 1, pp.33-39

Belge Tipi: Makale

Yayın Tarihi: 4/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000448305

Sıklık: Üç Aylık

eISSN: 2687-475X

pISSN: 2687-475X

DOI: https://doi.org/10.15671/hjbc.520248

Sayı

Yazarlar:

Seda YÜKSEKDANACI | Demet ASTLEY | İhsan YAŞA

Yayıncı:

Hacettepe University

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Hacettepe Journal of Biology and Chemistry 2020 Vol.48 Issue 1, pp.33-39

Belge Tipi:

Makale

Yayın Tarihi:

4/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000448305

Sıklık:

Üç Aylık

eISSN:

2687-475X

pISSN:

2687-475X

DOI:

https://doi.org/10.15671/hjbc.520248