Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

Tivanani V D Mahendra; Santosh Rahul; Ksv Ramesh; Swetha Pasupuleti; Sai Keerthi Velagala; Vyshnavi Mulakala

Makale detayları

Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

Yazarlar:

Tivanani V D Mahendra | Santosh Rahul | Ksv Ramesh | Swetha Pasupuleti | Sai Keerthi Velagala | Vyshnavi Mulakala

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.8-13

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311470

pISSN:

2630-6158

Anahtar kelimeler:

Özet:

 Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement GIC doped with 3 and 5 ww titanium dioxide nanoparticles TiO2-NPs, and to evaluate their antibacterial properties. Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3 and 5 ww modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. The samples were quantified over four-time periods: 24 hours, two months, four months, and six months, using inductively coupled plasma mass spectroscopy ICP-MS, antibacterial properties were evaluated by means of colony forming count CFU method. Results: The amount of titanium ions released from the discs that received 3ww TiO2 was highest in the first two months, with no significant release at successive intervals. Also, the second group, which included 5 ww TiO2, saw a considerable ion release at every interval, with the second month seeing the maximum release. The levels in the 5 ww group were consistently higher when the two concentrations were compared at each of the four time points, indicating a considerable increase in titanium release and antibacterial property with a concentration increase from 3 to 5. Conclusion: 3 and 5 ww concentrations may be considered safe and exhibit significant antimicrobial effect, titanium ions were discharged at higher rates in 5 ww modified GIC containing TiO2-NPs than in 3 ww modified GIC containing TiO2-NPs.

 Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement GIC doped with 3 and 5 ww titanium dioxide nanoparticles TiO2-NPs, and to evaluate their antibacterial properties. Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3 and 5 ww modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. The samples were quantified over four-time periods: 24 hours, two months, four months, and six months, using inductively coupled plasma mass spectroscopy ICP-MS, antibacterial properties were evaluated by means of colony forming count CFU method. Results: The amount of titanium ions released from the discs that received 3ww TiO2 was highest in the first two months, with no significant release at successive intervals. Also, the second group, which included 5 ww TiO2, saw a considerable ion release at every interval, with the second month seeing the maximum release. The levels in the 5 ww group were consistently higher when the two concentrations were compared at each of the four time points, indicating a considerable increase in titanium release and antibacterial property with a concentration increase from 3 to 5. Conclusion: 3 and 5 ww concentrations may be considered safe and exhibit significant antimicrobial effect, titanium ions were discharged at higher rates in 5 ww modified GIC containing TiO2-NPs than in 3 ww modified GIC containing TiO2-NPs.

 Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement GIC doped with 3 and 5 ww titanium dioxide nanoparticles TiO2-NPs, and to evaluate their antibacterial properties. Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3 and 5 ww modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. The samples were quantified over four-time periods: 24 hours, two months, four months, and six months, using inductively coupled plasma mass spectroscopy ICP-MS, antibacterial properties were evaluated by means of colony forming count CFU method. Results: The amount of titanium ions released from the discs that received 3ww TiO2 was highest in the first two months, with no significant release at successive intervals. Also, the second group, which included 5 ww TiO2, saw a considerable ion release at every interval, with the second month seeing the maximum release. The levels in the 5 ww group were consistently higher when the two concentrations were compared at each of the four time points, indicating a considerable increase in titanium release and antibacterial property with a concentration increase from 3 to 5. Conclusion: 3 and 5 ww concentrations may be considered safe and exhibit significant antimicrobial effect, titanium ions were discharged at higher rates in 5 ww modified GIC containing TiO2-NPs than in 3 ww modified GIC containing TiO2-NPs.

 Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement GIC doped with 3 and 5 ww titanium dioxide nanoparticles TiO2-NPs, and to evaluate their antibacterial properties. Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3 and 5 ww modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. The samples were quantified over four-time periods: 24 hours, two months, four months, and six months, using inductively coupled plasma mass spectroscopy ICP-MS, antibacterial properties were evaluated by means of colony forming count CFU method. Results: The amount of titanium ions released from the discs that received 3ww TiO2 was highest in the first two months, with no significant release at successive intervals. Also, the second group, which included 5 ww TiO2, saw a considerable ion release at every interval, with the second month seeing the maximum release. The levels in the 5 ww group were consistently higher when the two concentrations were compared at each of the four time points, indicating a considerable increase in titanium release and antibacterial property with a concentration increase from 3 to 5. Conclusion: 3 and 5 ww concentrations may be considered safe and exhibit significant antimicrobial effect, titanium ions were discharged at higher rates in 5 ww modified GIC containing TiO2-NPs than in 3 ww modified GIC containing TiO2-NPs.

Makale detayları

Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

Yazarlar:

Tivanani V D Mahendra | Santosh Rahul | Ksv Ramesh | Swetha Pasupuleti | Sai Keerthi Velagala | Vyshnavi Mulakala

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.8-13

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311470

pISSN:

2630-6158

Antibacterial

Glass ionomer cement

Ion release

saliva

Titanium dioxide

Sayı

Makale detayları

Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

Yazarlar: Tivanani V D Mahendra | Santosh Rahul | Ksv Ramesh | Swetha Pasupuleti | Sai Keerthi Velagala | Vyshnavi Mulakala

Yayıncı: Istanbul University

Ana Başlıklar: Dentistry (Other)

Dergi: European Oral Research Vol.58 Issue 1, pp.8-13

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001311470

pISSN: 2630-6158

Antibacterial

Glass ionomer cement

Ion release

saliva

Titanium dioxide

Sayı

Yazarlar:

Tivanani V D Mahendra | Santosh Rahul | Ksv Ramesh | Swetha Pasupuleti | Sai Keerthi Velagala | Vyshnavi Mulakala

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.8-13

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311470

pISSN:

2630-6158