Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions

Murat Sami BERKMAN; Kadri GÜLEÇ

Makale detayları

Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions

Yazarlar:

Murat Sami BERKMAN | Kadri GÜLEÇ

Yayıncı:

Istanbul University

Ana Başlıklar:

Farmakoloji ve terapötik | Sağlık teşvikleri

Dergi:

İstanbul Journal of Pharmacy 2021 Vol.51 Issue 1, pp.42-49

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000512869

Sıklık:

Aylık

eISSN:

2587-2087

Özet:

 

Background and Aims: This study aims to develop and evaluate a practical approach for the complicated area and centroid calculation of stable microemulsion regions. Pseudo ternary phase diagrams are used to determine the region of microemulsion existence. The effect of various surfactant/co-surfactant weight ratios on the extent of a stable microemulsion area can easily be observed with these diagrams. Furthermore, the optimum formulations are selected using the centroid of the microemulsion region. Methods: Microemulsion formulations were prepared by changing the weight ratios of the components. The titration method was used at a constant temperature. A pseudo ternary phase diagram was constructed using the spots of the stable microemulsion formulations. Results: The area and centroid of the stable microemulsion region were calculated by using the formulas manually and the macro edited for Microsoft® Excel. Both results were the same. The macro was user-friendly, easy to use, and worked well in Microsoft® Excel. Conclusion: Definitions, formulas, algorithms, and calculations used in this research will be constructive for everyone interested in this field and can be modified very easily in every different case.

Makale detayları

Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions

Yazarlar: Murat Sami BERKMAN | Kadri GÜLEÇ

Yayıncı: Istanbul University

Ana Başlıklar: Farmakoloji ve terapötik | Sağlık teşvikleri

Dergi: İstanbul Journal of Pharmacy 2021 Vol.51 Issue 1, pp.42-49

Belge Tipi: Makale

Yayın Tarihi: 4/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000512869

Sıklık: Aylık

eISSN: 2587-2087

Sayı

Yazarlar:

Murat Sami BERKMAN | Kadri GÜLEÇ

Yayıncı:

Istanbul University

Ana Başlıklar:

Farmakoloji ve terapötik | Sağlık teşvikleri

Dergi:

İstanbul Journal of Pharmacy 2021 Vol.51 Issue 1, pp.42-49

Belge Tipi:

Makale

Yayın Tarihi:

4/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000512869

Sıklık:

Aylık

eISSN:

2587-2087