Evaluation of the Uric Acid/Albumin Ratio in Acute Pericarditis Patients: Implications for Recurrence Rates and Hospitalization Duration

Azmi Eyiol; Hatice Eyiol; Ahmet Faruk Ay

Makale detayları

Evaluation of the Uric Acid/Albumin Ratio in Acute Pericarditis Patients: Implications for Recurrence Rates and Hospitalization Duration

Yazarlar:

Azmi Eyiol | Hatice Eyiol | Ahmet Faruk Ay

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.34 Issue 5, pp.696-701

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001330477

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 Aim: Acute pericarditis is inflammation of the pericardium, the membrane surrounding the heart. It typically presents with sudden chest pain, fever and general malaise. The uric acidalbumin ratio can help assess patients inflammatory status and monitor their response to treatment. Our aim is to evaluate the effect of uric acidalbumin ratio on the probability of recurrence and hospital stay in pericarditis patients. Methods: This study is designed as a retrospective cohort study. Patients demographic information, clinical findings and laboratory tests were evaluated. Treatment data were collected, including medications used NSAIDs, colchicine, corticosteroids, duration of treatment, and length of hospital stay. Recurrence cases, hospital stays and the need for additional treatment were evaluated. Results: The median age was 42 years, with a range of 18 to 65 years. The uric acidalbumin ratio showed a significant positive correlation with CRP ρ  0.182, p  0.005 and troponin levels ρ  0.483, p  0.001, indicating its association with inflammatory and cardiac stress markers. Additionally, a negative correlation was observed with hemoglobin levels ρ  -0.535, p  0.001. Conclusion: The uric acidalbumin ratio offers a novel and insightful approach to evaluating acute pericarditis, providing a composite marker of inflammation, oxidative stress, and nutritional status. Its significant associations with clinical severity and recurrence risk highlight its potential role in guiding patient management and improving outcomes.

 Aim: Acute pericarditis is inflammation of the pericardium, the membrane surrounding the heart. It typically presents with sudden chest pain, fever and general malaise. The uric acidalbumin ratio can help assess patients inflammatory status and monitor their response to treatment. Our aim is to evaluate the effect of uric acidalbumin ratio on the probability of recurrence and hospital stay in pericarditis patients. Methods: This study is designed as a retrospective cohort study. Patients demographic information, clinical findings and laboratory tests were evaluated. Treatment data were collected, including medications used NSAIDs, colchicine, corticosteroids, duration of treatment, and length of hospital stay. Recurrence cases, hospital stays and the need for additional treatment were evaluated. Results: The median age was 42 years, with a range of 18 to 65 years. The uric acidalbumin ratio showed a significant positive correlation with CRP ρ  0.182, p  0.005 and troponin levels ρ  0.483, p  0.001, indicating its association with inflammatory and cardiac stress markers. Additionally, a negative correlation was observed with hemoglobin levels ρ  -0.535, p  0.001. Conclusion: The uric acidalbumin ratio offers a novel and insightful approach to evaluating acute pericarditis, providing a composite marker of inflammation, oxidative stress, and nutritional status. Its significant associations with clinical severity and recurrence risk highlight its potential role in guiding patient management and improving outcomes.

 Aim: Acute pericarditis is inflammation of the pericardium, the membrane surrounding the heart. It typically presents with sudden chest pain, fever and general malaise. The uric acidalbumin ratio can help assess patients inflammatory status and monitor their response to treatment. Our aim is to evaluate the effect of uric acidalbumin ratio on the probability of recurrence and hospital stay in pericarditis patients. Methods: This study is designed as a retrospective cohort study. Patients demographic information, clinical findings and laboratory tests were evaluated. Treatment data were collected, including medications used NSAIDs, colchicine, corticosteroids, duration of treatment, and length of hospital stay. Recurrence cases, hospital stays and the need for additional treatment were evaluated. Results: The median age was 42 years, with a range of 18 to 65 years. The uric acidalbumin ratio showed a significant positive correlation with CRP ρ  0.182, p  0.005 and troponin levels ρ  0.483, p  0.001, indicating its association with inflammatory and cardiac stress markers. Additionally, a negative correlation was observed with hemoglobin levels ρ  -0.535, p  0.001. Conclusion: The uric acidalbumin ratio offers a novel and insightful approach to evaluating acute pericarditis, providing a composite marker of inflammation, oxidative stress, and nutritional status. Its significant associations with clinical severity and recurrence risk highlight its potential role in guiding patient management and improving outcomes.

 Amaç: Akut perikardit, kalbi çevreleyen zar olan perikardın iltihaplanmasıdır. Tipik olarak ani göğüs ağrısı, ateş ve genel halsizlikle kendini gösterir. Ürik asitalbümin oranı, hastaların inflamatuar durumunu değerlendirmeye ve tedaviye yanıtlarını izlemeye yardımcı olabilir. Amacımız, ürik asitalbümin oranının perikardit hastalarında tekrarlama ve hastanede kalış olasılığı üzerindeki etkisini değerlendirmektir. Yöntemler: Bu çalışma retrospektif bir kohort çalışması olarak tasarlanmıştır ve toplam 233 hasta değerlendirilmiştir. Hastaların demografik bilgileri, klinik bulguları ve laboratuvar testleri değerlendirilmiştir. Kullanılan ilaçlar NSAIDler, kolşisin, kortikosteroidler, tedavi süresi ve hastanede kalış süresi dahil olmak üzere tedavi verileri toplandı. Tekrarlama vakaları, hastanede kalış süreleri ve ek tedaviye ihtiyaç olup olmadığı değerlendirildi. Bulgular: Ortanca yaş 42 idi ve aralık 18 ila 65 yıldı. Ürik asitalbümin oranı, CRP ρ  0,182, p  0,005 ve troponin seviyeleri ρ  0,483, p  0,001 ile anlamlı bir pozitif korelasyon gösterdi ve bu da onun inflamatuar ve kardiyak stres belirteçleriyle ilişkisini gösteriyor. Ek olarak, hemoglobin seviyeleriyle negatif bir korelasyon gözlendi ρ  -0,535, p  0,001. Sonuçlar: Ürik asitalbümin oranı, akut perikarditi değerlendirmek için yeni ve içgörülü bir yaklaşım sunarak, inflamasyon, oksidatif stres ve beslenme durumunun bileşik bir belirtecini sağlar. Klinik şiddet ve tekrarlama riskiyle olan anlamlı ilişkileri, hasta yönetimini yönlendirme ve sonuçları iyileştirmedeki potansiyel rolünü vurgular.

Makale detayları

Evaluation of the Uric Acid/Albumin Ratio in Acute Pericarditis Patients: Implications for Recurrence Rates and Hospitalization Duration

Yazarlar:

Azmi Eyiol | Hatice Eyiol | Ahmet Faruk Ay

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.34 Issue 5, pp.696-701

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001330477

pISSN:

2602-3741

Pericarditis

Uric Acid/Albumin Ratio

Recurrence

HospitalizationPerikardit

Ürik Asit/Albümin Oranı

Tekrarlama

Hastaneye Yatış

Sayı

Makale detayları

Yazarlar: Azmi Eyiol | Hatice Eyiol | Ahmet Faruk Ay

Yayıncı: Selcuk University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Genel Tıp Dergisi Vol.34 Issue 5, pp.696-701

Belge Tipi: Makale

Yayın Tarihi: 10/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001330477

pISSN: 2602-3741

Sayı

Yazarlar:

Azmi Eyiol | Hatice Eyiol | Ahmet Faruk Ay

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Genel Tıp Dergisi Vol.34 Issue 5, pp.696-701

Belge Tipi:

Makale

Yayın Tarihi:

10/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001330477

pISSN:

2602-3741