Essential oil profile and biological activity of the paleoendemic species Salvia dorystaechas B.T. Drew

Yavuz Bülent Köse; Zeynep Gülcan; Gökalp İşcan; Mine Kürkçüoğlu

Makale detayları

Essential oil profile and biological activity of the paleoendemic species Salvia dorystaechas B.T. Drew

Yazarlar:

Yavuz Bülent Köse | Zeynep Gülcan | Gökalp İşcan | Mine Kürkçüoğlu

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Botany

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 2, pp.420-428

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001340477

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 Salvia dorystaechas B.T. Drew syn. Dorystaechas hastata Boiss.  Heldr. ex Benth. is an endemic plant native to Antalya and its surroundings, known as Dağ çayı and Çalba Çayı. In the present study, n-hexane, ethyl acetate, ethanol 70 extracts and essential oil were obtained from the aerial parts of S. dorystaechas. The oil was obtained by the hydrodistillation method. The chemical composition of oil was determined by GCFID and GCMS analysis. Twenty-seven compounds were identified representing 99 of the oil. 1,8-cineole 26.4, myrcene 19.2 and α-pinene 10.1 were determined as the main components. The extracts of the plant were screened for antioxidant activity by using a DPPH free radical scavenging assay. The ordering of extracts in terms of antioxidant activity from highest to lowest was ethyl acetate, ethanol 70 and n-hexane. The extracts and hydrodistilled oil of S. dorystaechas were evaluated for their antimicrobial activity using standard broth microdilution protocols. The ethyl acetate extract exhibited the highest antibacterial and anticandidal activities against S. aureus, S. typhimurium, C. utilis, and C. tropicalis, with a minimum inhibitory concentration MIC of 62.5 µgmL. The essential oil and the ethanolic extract demonstrated moderate to weak inhibitory effects 62,5 to 2000 µgmL, MIC against tested microorganisms. S. dorystaechas extracts demonstrate strong antimicrobial properties against various pathogens, suggesting potential use as a natural antibiotic, especially in light of increasing antibiotic resistance. Furthermore, the plants aromatic components may be beneficial in aromatherapy. S. dorystaechas presents a promising candidate for natural therapeutic interventions, warranting further investigation into its pharmacological benefits.

 Salvia dorystaechas B.T. Drew syn. Dorystaechas hastata Boiss.  Heldr. ex Benth. is an endemic plant native to Antalya and its surroundings, known as Dağ çayı and Çalba Çayı. In the present study, n-hexane, ethyl acetate, ethanol 70 extracts and essential oil were obtained from the aerial parts of S. dorystaechas. The oil was obtained by the hydrodistillation method. The chemical composition of oil was determined by GCFID and GCMS analysis. Twenty-seven compounds were identified representing 99 of the oil. 1,8-cineole 26.4, myrcene 19.2 and α-pinene 10.1 were determined as the main components. The extracts of the plant were screened for antioxidant activity by using a DPPH free radical scavenging assay. The ordering of extracts in terms of antioxidant activity from highest to lowest was ethyl acetate, ethanol 70 and n-hexane. The extracts and hydrodistilled oil of S. dorystaechas were evaluated for their antimicrobial activity using standard broth microdilution protocols. The ethyl acetate extract exhibited the highest antibacterial and anticandidal activities against S. aureus, S. typhimurium, C. utilis, and C. tropicalis, with a minimum inhibitory concentration MIC of 62.5 µgmL. The essential oil and the ethanolic extract demonstrated moderate to weak inhibitory effects 62,5 to 2000 µgmL, MIC against tested microorganisms. S. dorystaechas extracts demonstrate strong antimicrobial properties against various pathogens, suggesting potential use as a natural antibiotic, especially in light of increasing antibiotic resistance. Furthermore, the plants aromatic components may be beneficial in aromatherapy. S. dorystaechas presents a promising candidate for natural therapeutic interventions, warranting further investigation into its pharmacological benefits.

 Salvia dorystaechas B.T. Drew syn. Dorystaechas hastata Boiss.  Heldr. ex Benth. is an endemic plant native to Antalya and its surroundings, known as Dağ çayı and Çalba Çayı. In the present study, n-hexane, ethyl acetate, ethanol 70 extracts and essential oil were obtained from the aerial parts of S. dorystaechas. The oil was obtained by the hydrodistillation method. The chemical composition of oil was determined by GCFID and GCMS analysis. Twenty-seven compounds were identified representing 99 of the oil. 1,8-cineole 26.4, myrcene 19.2 and α-pinene 10.1 were determined as the main components. The extracts of the plant were screened for antioxidant activity by using a DPPH free radical scavenging assay. The ordering of extracts in terms of antioxidant activity from highest to lowest was ethyl acetate, ethanol 70 and n-hexane. The extracts and hydrodistilled oil of S. dorystaechas were evaluated for their antimicrobial activity using standard broth microdilution protocols. The ethyl acetate extract exhibited the highest antibacterial and anticandidal activities against S. aureus, S. typhimurium, C. utilis, and C. tropicalis, with a minimum inhibitory concentration MIC of 62.5 µgmL. The essential oil and the ethanolic extract demonstrated moderate to weak inhibitory effects 62,5 to 2000 µgmL, MIC against tested microorganisms. S. dorystaechas extracts demonstrate strong antimicrobial properties against various pathogens, suggesting potential use as a natural antibiotic, especially in light of increasing antibiotic resistance. Furthermore, the plants aromatic components may be beneficial in aromatherapy. S. dorystaechas presents a promising candidate for natural therapeutic interventions, warranting further investigation into its pharmacological benefits.

 Salvia dorystaechas B.T. Drew syn. Dorystaechas hastata Boiss.  Heldr. ex Benth. is an endemic plant native to Antalya and its surroundings, known as Dağ çayı and Çalba Çayı. In the present study, n-hexane, ethyl acetate, ethanol 70 extracts and essential oil were obtained from the aerial parts of S. dorystaechas. The oil was obtained by the hydrodistillation method. The chemical composition of oil was determined by GCFID and GCMS analysis. Twenty-seven compounds were identified representing 99 of the oil. 1,8-cineole 26.4, myrcene 19.2 and α-pinene 10.1 were determined as the main components. The extracts of the plant were screened for antioxidant activity by using a DPPH free radical scavenging assay. The ordering of extracts in terms of antioxidant activity from highest to lowest was ethyl acetate, ethanol 70 and n-hexane. The extracts and hydrodistilled oil of S. dorystaechas were evaluated for their antimicrobial activity using standard broth microdilution protocols. The ethyl acetate extract exhibited the highest antibacterial and anticandidal activities against S. aureus, S. typhimurium, C. utilis, and C. tropicalis, with a minimum inhibitory concentration MIC of 62.5 µgmL. The essential oil and the ethanolic extract demonstrated moderate to weak inhibitory effects 62,5 to 2000 µgmL, MIC against tested microorganisms. S. dorystaechas extracts demonstrate strong antimicrobial properties against various pathogens, suggesting potential use as a natural antibiotic, especially in light of increasing antibiotic resistance. Furthermore, the plants aromatic components may be beneficial in aromatherapy. S. dorystaechas presents a promising candidate for natural therapeutic interventions, warranting further investigation into its pharmacological benefits.

Makale detayları

Essential oil profile and biological activity of the paleoendemic species Salvia dorystaechas B.T. Drew

Yazarlar:

Yavuz Bülent Köse | Zeynep Gülcan | Gökalp İşcan | Mine Kürkçüoğlu

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Botany

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 2, pp.420-428

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001340477

pISSN:

2148-6905

Salvia dorystaechas

Dorystoechas hastata

Antioxidant activity

Antimicrobial activity

GC-GC/MSSalvia dorystaechas

Dorystoechas hastata

Antioxidant activity

Antimicrobial activity

GC-GC/MS

Sayı

Makale detayları

Yazarlar: Yavuz Bülent Köse | Zeynep Gülcan | Gökalp İşcan | Mine Kürkçüoğlu

Yayıncı: İzzet KARA

Ana Başlıklar: Pharmaceutical Botany

Dergi: International Journal of Secondary Metabolite Vol.12 Issue 2, pp.420-428

Belge Tipi: Makale

Yayın Tarihi: 1/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001340477

pISSN: 2148-6905

Sayı

Yazarlar:

Yavuz Bülent Köse | Zeynep Gülcan | Gökalp İşcan | Mine Kürkçüoğlu

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Botany

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 2, pp.420-428

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001340477

pISSN:

2148-6905