The additional diagnostic value of NLR and PLR for CA-125 in the differential diagnosis of endometrioma and benign ovarian cysts in women of reproductive age: a retrospective case-control study

Ziya KALEM; Çoşkun ŞİMŞİR; Batuhan BAKIRARAR; Müberra NAMLI KALEM

doi:https://doi.org/10.18621/eurj.483442

Makale detayları

The additional diagnostic value of NLR and PLR for CA-125 in the differential diagnosis of endometrioma and benign ovarian cysts in women of reproductive age: a retrospective case-control study

Yazarlar:

Ziya KALEM | Çoşkun ŞİMŞİR | Batuhan BAKIRARAR | Müberra NAMLI KALEM

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Jinekoloji ve diğer tıbbi uzmanlık alanları

Dergi:

The European Research Journal 2020 Vol.6 Issue 2, pp.111-119

Belge Tipi:

Makale

Yayın Tarihi:

3/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662379

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.483442

Özet:

 


Objectives:
Aim of this study is to investigate
the diagnostic value of neutrophil/lymphocyte ratio (NLR) and
platelet/lymphocyte ratio (PLR) for cancer antigen-125 (CA-125) in a differential
diagnosis of endometrioma from benign ovarian cysts. 


Methods: In this retrospective study, the medical data of a total of 213 patients
aged < 40 years who underwent laparoscopic or laparotomic surgery for
ovarian cysts between April 2015 and June 2018 were analyzed. The patients were
divided into two groups, as those with endometriomas and those with other benign
ovarian cysts, all which had been confirmed histopathologically. Data on age,
body mass index (BMI), preoperative US findings, complete blood count analysis
results, follicle-stimulating hormone (FSH) levels, and the presence of
dysmenorrhea, dyspareunia and chronic pelvic pain were recorded. 


Results: NLR, PLR and CA-125 were increased in the patients with endometrioma,
although increases in the NLR and PLR alone or combined did not contribute to
the sensitivity or specificity of CA-125. 









Conclusions: The results of our study suggest that NLR and PLR did not contribute to
the diagnostic value of CA-125 in the preoperative differential diagnosis of
endometriomas or other benign ovarian cysts. In addition, CA-125 was not
associated with clinical symptoms, although a relationship was identified between
NLR and dysmenorrhea, and between PLR and lesion size, which may be the
research focus of further studies. 



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Makale detayları

The additional diagnostic value of NLR and PLR for CA-125 in the differential diagnosis of endometrioma and benign ovarian cysts in women of reproductive age: a retrospective case-control study

Yazarlar: Ziya KALEM | Çoşkun ŞİMŞİR | Batuhan BAKIRARAR | Müberra NAMLI KALEM

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Jinekoloji ve diğer tıbbi uzmanlık alanları

Dergi: The European Research Journal 2020 Vol.6 Issue 2, pp.111-119

Belge Tipi: Makale

Yayın Tarihi: 3/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000662379

Sıklık: İki Aylık

eISSN: 2149-3189

DOI: https://doi.org/10.18621/eurj.483442

Sayı

Yazarlar:

Ziya KALEM | Çoşkun ŞİMŞİR | Batuhan BAKIRARAR | Müberra NAMLI KALEM

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Jinekoloji ve diğer tıbbi uzmanlık alanları

Dergi:

The European Research Journal 2020 Vol.6 Issue 2, pp.111-119

Belge Tipi:

Makale

Yayın Tarihi:

3/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662379

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.483442