Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles

Kemal SANCAK; Yasemin ÜNVER; Dilek ÜNLÜER; Esra DÜĞDÜ; Gülcan KÖR

doi:https://doi.org/10.3906/vet-1302-34

Makale detayları

Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles

Yazarlar:

Kemal SANCAK | Yasemin ÜNVER | Dilek ÜNLÜER | Esra DÜĞDÜ | Gülcan KÖR

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 3, pp.457-466

Belge Tipi:

Makale

Yayın Tarihi:

2/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000727628

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/vet-1302-34

Özet:

 

A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H-  1,2,4-triazoles (3a-g) were obtained by reaction of ethyl  N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy  phenyl)ethanamine (2).  Compounds 4d, e, and g were synthesized from  the reaction of corresponding compounds 3d, e, and g with BBr3,  respectively.  The 10 new compounds synthesized were characterized by  elemental analyses, IR, 1H-NMR, and 13C-NMR spectral data.  The  structure of compound 3g was inferred through IR, 1H-, 13C-NMR,  elemental analyses, and X-ray spectral techniques.  In addition, the  newly synthesized chemicals were screened for their antioxidant  properties.  Among the chemicals tested, 4d, e, and g exhibited the  highest degree of antioxidant activity.

 

A series of new 4-(3,4dimethoxyphenethyl)-3,5-akyl/aryl-4H-  1,2,4-triazoles (3a-g) were obtained by reaction of ethyl  N'-(alkylidene/arylidene)hydrazonate (1) and 2-(3,4-dimethoxy  phenyl)ethanamine (2).  Compounds 4d, e, and g were synthesized from  the reaction of corresponding compounds 3d, e, and g with BBr3,  respectively.  The 10 new compounds synthesized were characterized by  elemental analyses, IR, 1H-NMR, and 13C-NMR spectral data.  The  structure of compound 3g was inferred through IR, 1H-, 13C-NMR,  elemental analyses, and X-ray spectral techniques.  In addition, the  newly synthesized chemicals were screened for their antioxidant  properties.  Among the chemicals tested, 4d, e, and g exhibited the  highest degree of antioxidant activity.

Makale detayları

Synthesis, characterization, and antioxidant activities of new trisubstituted triazoles

Yazarlar: Kemal SANCAK | Yasemin ÜNVER | Dilek ÜNLÜER | Esra DÜĞDÜ | Gülcan KÖR

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2012 Vol.36 Issue 3, pp.457-466

Belge Tipi: Makale

Yayın Tarihi: 2/2012

Belge Dili: İngilizce

Document ID (Org No.): 2000727628

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/vet-1302-34

Sayı

Yazarlar:

Kemal SANCAK | Yasemin ÜNVER | Dilek ÜNLÜER | Esra DÜĞDÜ | Gülcan KÖR

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 3, pp.457-466

Belge Tipi:

Makale

Yayın Tarihi:

2/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000727628

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/vet-1302-34